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International Classification of Diseases for Oncology

The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries.

It is currently in its third revision.



The classification has two axes:


The morphology axis is for the morphology of the tumor.

This axis has additional importance, because the Systematized Nomenclature of Medicine has adopted ICD-O's classification of morphology.

Examples of codes

(8000-8009) Not otherwise specified
(8010-8790) Epithelial
(8800-9370) Connective tissue
  • (8840-8849) Myxomatous neoplasms
    • (M8840/0) Myxoma, NOS
  • (9000-9030) Fibroepithelial Neoplasms
    • (M9000/0) Brenner tumor, NOS
  • (9040-9049) Synovial-Like Neoplasms
    • (M9040/3) Synovial sarcoma, NOS
  • (9170-9179) Lymphatic vessel tumors
    • (M9170/0) Lymphangioma, NOS
    • (M9173/0) Cystic lymphangioma
(9380-9589) Nervous system
  • (9530-9539) Meningiomas
  • (9580-9589) Granular cell tumors and Alveolar soft part sarcoma
(9590-9999) Hematologic (Leukemias, Lymphomas and related disorders)
  • (9740-9749) Mast cell Tumors
    • (M9740/1) Mastocytoma, NOS or Extracutaneous mastocytoma
    • (M9740/3) Mast cell sarcoma
    • (M9741/1) Malignant mastocytosis or Indolent systemic mastocytosis
    • (M9741/3) Aggressive systemic mastocytosis or Systemic mastocytosis with associated clonal, hematological non-mast cell lineage disease
    • (M9742/3) Mast cell leukemia
    • (M9751/1) Langerhans cell histiocytosis
    • (M9755/3) Histiocytic sarcoma
    • (M9756/3) Langerhans cell sarcoma
    • (M9757/3) Dendritic cell sarcoma, NOS or Interdigitating dendritic cell sarcoma/tumor
    • (M9758/3) Follicular dendritic cell sarcoma/tumor
-- Lymphoid leukemias, and related conditions
  • (9800-9809) Leukemias, NOS
    • (M9800/3) Leukemia, NOS
    • (M9805/3) Acute leukemia of ambiguous lineage
    • (M9801/3) Acute leukemia, NOS
-- Myeloid leukemias, and related conditions
  • (9890-9899) Monocytic leukemias
    • (M9890/3) Monocytic leukemia, NOS (FAB-M5)
    • (M9891/3) Acute monoblastic and monocytic leukemia (FAB M5)
    • (M9895/3) Acute myeloid leukemia multilineage dysplasia
    • (M9896/3) AML with t(8;21)(q22;q22), AML1/ETO
    • (M9897/3) AML with 11q23 (MLL) abnormalities
-- Other


The topography axis is for the topographical codes of the tumor's site. It is standardized with the C section of ICD-10

There were no changes in the topography axis between ICD-O-2 and ICD-O-3.

See List of ICD-10 codes#.28C00-C97.29 Malignant Neoplasms for examples.

See also


  • - overview, includes link to Excel spreadsheet with codes at National Cancer Institute
  • Overview at National Cancer Institute
  • Word document - malignancies only at National Cancer Institute
  • Overview at University hospital Gießen und Marburg
  • Download table at DIMDI
  • Codes at IARC
  • 1st, 2nd, and 3rd editions at
  • List at The National Cancer Registry Ireland
  • List at London School of Hygiene & Tropical Medicine
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "International_Classification_of_Diseases_for_Oncology". A list of authors is available in Wikipedia.
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