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Sézary's disease (or "Sézary syndrome") is a type of cutaneous lymphoma characterized by Albert Sézary.
"Sézary's cells" are T-cells that have pathological quantities of mucopolysaccharides.
Sézary's disease is sometimes considered a late stage of mycosis fungoides.
Additional recommended knowledge
Sezary syndrome and Mycosis Fungoides are T-cell lymphomas whose primary manifestation is in the skin.
HTLV has thought to have been associated with both of the above cutaneous mycoses.
The hallmark symptoms for Sezary Syndrome are (1) Generalized erythroderma (2)Lymphadenopathy, and (3) Atypical T-cells ("Sezary cells") in the peripheral blood.
Vorinostat (Zolinza®) is a second-line drug for CTCL. Treatments are often used in combination.
Categories: Hematology | Types of cancer
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sézary's_disease". A list of authors is available in Wikipedia.|