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Fighting Cancer from a Chair

Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

27-Jan-2021 Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum atoms. Unlike cisplatin, this drug also directly inhibits metas ... more

A new mechanism protects against cancer cell migration and neuron hyperexcitability

27-Jan-2021 G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in the journal Cell. The study was led by scientists from the University of Innsbruck and the German Cancer Research C ... more

Detect neurodegenerative diseases such as Alzheimer's by a simple eye scan?

Milestone on the way to early diagnostics: Researchers use spectroscopic means to decipher the biochemical composition of the retina

27-Jan-2021 Diagnosing Alzheimer's disease through a non-invasive eye scan long before symptoms appear: a European research team involving Leibniz IPHT has come one step closer to achieving this goal. Using a laser-based method, the researchers have succeeded in discriminating between healthy and Alzhe ... more

Scientists use novel ink to 3D-print ‘bone’ with living cells

3D printers may one day become a permanent fixture of the operating theatre

27-Jan-2021 Scientists from UNSW Sydney have developed a ceramic-based ink that may allow surgeons in the future to 3D-print bone parts complete with living cells that could be used to repair damaged bone tissue. Using a 3D-printer that deploys a special ink made up of calcium phosphate, the scientists ... more

Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates

Company continues Development of Two Investigational Therapeutic Candidates

26-Jan-2021 Merck, known as MSD outside the United States and Canada, announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeut ... more

Distribution of COVID-19 vaccines with delivery drones

Wingcopter raises $22M to advance technology leadership in drone delivery, announces serial production

26-Jan-2021 Wingcopter, the German developer, manufacturer and operator of unmanned delivery drones for commercial and humanitarian applications, has secured $22 million in Series A funding. Wingcopter will use the funds to strengthen its leadership in drone-based logistics, with a special focus on hea ... more

Tracing the path of leukemia

Chemical signature of chronic lymphocytic leukemia already present in the precancerous stage

26-Jan-2021 B-cell lymphocytosis, a condition in which individuals have increased levels of particular white blood cells, in some cases leads to blood cancer. As an international team of researchers now shows in samples from patients, both diseases exhibit similar epigenetic signatures that are forming ... more

New separation technology for biomolecules

i3 Membrane receives 7 figure sum for development and market launch

26-Jan-2021 Four investors are financing the further growth of i3 Membrane GmbH. High-tech venture capital investor HTGF from Bonn, Germany, and three private investors are together investing a 7 figure sum in the further development and market launch of new separation technology for biological molecul ... more

A treatment for every kind of cancer

Start-up recently received seed funding of USD 30 million with a view to making universal, ready-to-use T cell cancer therapies a reality

26-Jan-2021 Researchers from the University of Basel have identified cells in the immune system that are able to attack a wide range of cancer cells. Through a start-up, they are now aiming to use their discovery to develop clinically applicable treatments that will mark the next milestone in cell-base ... more

Detailed tumour profiling

Better determine which treatment will best match every patient’s cancer and thus be most effective.

25-Jan-2021 As part of a clinical study involving patients from the University Hospitals in Zurich and Basel, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumours. Their goal is to help physicians to better determine which treatm ... more

All news

New separation technology for biomolecules

i3 Membrane receives 7 figure sum for development and market launch

26-Jan-2021 Four investors are financing the further growth of i3 Membrane GmbH. High-tech venture capital investor HTGF from Bonn, Germany, and three private investors are together investing a 7 figure sum in the further development and market launch of new separation technology for biological molecul ... more

Nanodiamonds feel the heat

Nanodiamond sensor can act as both heat sources and thermometers, and may lead to a new set of heat-based treatments for killing bacteria or cancer cells

19-Jan-2021 A team of scientists from Osaka University, The University of Queensland, and the National University of Singapore's Faculty of Engineering used tiny nanodiamonds coated with a heat-releasing polymer to probe the thermal properties of cells. When irradiated with light from a laser, the sens ... more

New and highly efficient method for SARS-CoV-2 mutation analysis

Mutations can be assigned directly without any intermediate mathematical steps

18-Jan-2021 The rapid spread of the newly emerging SARS-CoV-2 virus variant B.1.1.7 in Great Britain and other countries shows, changes in the genome of the SARS-CoV-2 virus can lead to new biological properties.  Most of the approximately 12,000 mutations in the genome of the SARS-CoV-2 virus that hav ... more

ZEISS Invests by Acquiring Majority Stake in arivis AG

ZEISS further expands its imaging technology capabilities for research microscopy with 3D and big image data software expertise

08-Dec-2020 ZEISS is expanding its imaging technology capabilities with 3D and big image data software by acquiring a majority stake in the imaging business of arivis. With this investment, ZEISS is further strengthening its software competencies and market position in 3D image visualization, image pro ... more

Animal-free method predicts nanoparticle toxicity for safer industrial materials

A step closer to safe-by-design material development

26-Nov-2020 Researchers at Helmholtz Zentrum München together with scientists across Europe developed a novel animal-free method to predict the toxic effect of nanoparticles to the human lung. The method aims to enable the safety-by-design development of safer industrial materials. Our lungs are expose ... more

New test to better assess environmental impact of substances

Researchers developed a test that investigates whether substances can cause inheritable changes in the genome of multicellular organisms such as insects

24-Nov-2020 Researchers of the Senckenberg Biodiversity and Climate Research Centre and the LOEWE Centre for Translational Biodiversity Genomics hope to increase the reliability of environmental impact tests of substances. To this end, they developed a test that investigates whether substances can caus ... more

analytica China 2020 concludes successfully

More than 1,000 new products point to future trends

24-Nov-2020 analytica China 2020 came to a successful conclusion on November 18, 2020 at the Shanghai New International Expo Centre. The show brought together 1,009 exhibitors (2018: 950) and 112 represented companies and partners. 23,652 professional visitors attended. With six exhibition halls, eight ... more

Study of hundreds of proteins in parallel

First highly scalable method developed to monitor protein levels and localizations in cells

20-Nov-2020 CeMM researchers have developed a highly scalable method which allows for the study of hundreds of proteins in parallel in order to monitor the changes of their levels and localization in the cell. This novel strategy is a notable contribution, not only to drug development for future treatm ... more

Novel label-free biosensor platform for innovate modern drug screening

lino Biotech closes seed financing round

19-Nov-2020 After almost a decade of initial invention and joint research on the Focal Molography technology at Roche, a leading player in the diagnostics and pharmaceutical area, and ETH Zurich as one of Europe’s most renowned research institutes, lino Biotech AG has licensed the technology to further ... more

Sorting out viruses with machine learning

Scientists develop a label-free method for identifying respiratory viruses which may lead to new rapid COVID-19 tests

19-Nov-2020 The ongoing global pandemic has created an urgent need for rapid tests that can diagnose the presence of the SARS-CoV-2 virus, the pathogen that causes COVID-19, and distinguish it from other respiratory viruses. Now, researchers from Japan have demonstrated a new system for single-virion i ... more

All news on bioanalytics

New separation technology for biomolecules

i3 Membrane receives 7 figure sum for development and market launch

26-Jan-2021 Four investors are financing the further growth of i3 Membrane GmbH. High-tech venture capital investor HTGF from Bonn, Germany, and three private investors are together investing a 7 figure sum in the further development and market launch of new separation technology for biological molecul ... more

Development of a small molecule that inhibits the replication of SARS-CoV-2 and other RNA viruses

Forbion invests USD 2.3M in seed financing of CoviCept Therapeutics

22-Jan-2021 Forbion, a European life sciences venture capital firm, announces a $2.3m seed investment in newly formed CoviCept Therapeutics, Inc., a California-based company that is developing a small molecule that inhibits the replication of SARS-CoV-2 (COVID-19) and other RNA viruses. CoviCept’s lead ... more

Red yeast from deep-sea sediment shows anticancer and antibacterial properties

On the trail of active ingredients from marine yeasts

21-Jan-2021 Numerous natural products are awaiting discovery in all kinds of natural habitats. Especially microorganisms such as bacteria or fungi are able to produce diverse natural products with high biomedical application potential in particular as antibiotics and anticancer agents. This includes th ... more

New biodegradable polyurethane foams are developed from wheat straw

21-Jan-2021 Every year around 734 million tons of wheat straw are produced worldwide, a large amount of waste, which is cheap and has had no well-defined use until now. Recently, the RNM-271 Chemical Engineering and FQM-383 NANOVAL Organic Chemistry research groups at the University of Córdoba have bee ... more

Transformation of lignin into tailor made particles for life science applications

LignoPure secures € 2.2 Million seed round

20-Jan-2021 LignoPure invented a unique approach to replace plastics through utilization of wood waste and the team just closed its seed round with HTGF, IFH and Tanovis AG to scale its own technology for the transformation of lignin – a byproduct of the pulp and paper industries and biorefineries – in ... more

Start-up ViGeneron announces research collaboration with Daiichi Sankyo

Evaluate vgAAV for novel ophthalmic gene therapy

19-Jan-2021 ViGeneron GmbH, a gene therapy company, announced a research collaboration to utilize its novel engineered adeno-associated virus (vgAAV) vectors with Daiichi Sankyo Company, Limited, for delivering a novel therapeutic protein to address an undisclosed target in a highly prevalent ophthalmi ... more

New pathways found for biotechnological degradation of industrial waste

Microorganism breaks down phenol under extreme conditions

19-Jan-2021 Scientists led by Dr Meina Neumann-Schaal of the Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH in Braunschweig, Lower Saxony, have characterised the breakdown of phenol by Saccharolobus solfataricus. Using methods from the fields of metabolomics and trans ... more

Designer cytokine makes paralyzed mice walk again

19-Jan-2021 Using gene therapy, a research team has succeeded for the first time in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves. To date, paralysis resulting from spinal cord damage has been irreparable. With a new therape ... more

CureVac’s COVID-19 Vaccine Candidate Demonstrated Efficient Protection of Non-Human Primates During SARS-CoV-2 Challenge Infection

12-Jan-2021 CureVac N.V. announced the publication of preclinical data demonstrating the induction of robust antibody and T cell responses of its COVID-19 vaccine candidate, CVnCoV, in non-human primates. Furthermore, rhesus macaques were shown to be protected from challenge infection with SARS-CoV-2 f ... more

Fujifilm to Invest Over 200 Billion yen to Establish New Large-Scale Cell Culture Manufacturing Site for Biopharmaceuticals in the U.S.A.

End-to-End Single-Site Solution from Drug Substances to Fill-Finish & Packaging

08-Jan-2021 FUJIFILM Corporation is making an investment of more than 200 Billion yen (2 Billion USD) to establish a new large-scale cell culture production site in the United States to accelerate the growth of its biopharmaceutical contract development and manufacturing business (CDMO). FUJIFILM Diosy ... more

All news on biotechnology

Detect neurodegenerative diseases such as Alzheimer's by a simple eye scan?

Milestone on the way to early diagnostics: Researchers use spectroscopic means to decipher the biochemical composition of the retina

27-Jan-2021 Diagnosing Alzheimer's disease through a non-invasive eye scan long before symptoms appear: a European research team involving Leibniz IPHT has come one step closer to achieving this goal. Using a laser-based method, the researchers have succeeded in discriminating between healthy and Alzhe ... more

New and highly efficient method for SARS-CoV-2 mutation analysis

Mutations can be assigned directly without any intermediate mathematical steps

18-Jan-2021 The rapid spread of the newly emerging SARS-CoV-2 virus variant B.1.1.7 in Great Britain and other countries shows, changes in the genome of the SARS-CoV-2 virus can lead to new biological properties.  Most of the approximately 12,000 mutations in the genome of the SARS-CoV-2 virus that hav ... more

New contrast mechanism improves xenon MRI

Enhanced speed, contrast, and information

14-Jan-2021 Xenon magnetic resonance imaging offers deep insights into the human body and opens up new possibilities in the diagnosis and treatment of diseases. Physicists from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin have now achieved a considerable improvement of th ... more

Detecting COVID-19 antibodies in 10-12 seconds

12-Jan-2021 Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic. In addition to testing, the platform will help to quantify patien ... more

Detecting CRISPR/Cas gene doping

An initial step toward a test to pinpoint athletes trying to gain an unfair advantage

11-Jan-2021 All athletes want to be at the top of their game when they compete, but some resort to nefarious approaches to achieve peak muscle growth, speed and agility. Recent developments in gene editing technology could tempt athletes to change their DNA to get an edge. Now, researchers reporting in ... more

A prognostic Alzheimer’s disease blood test in the symptom-free stage

Memory deficit is a normal side effect of aging. At what point does memory loss become pathological?

08-Jan-2021 Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer’s disease in people who were clinically diagnosed as not having Alzheimer’s disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD). The researchers analyzed blood ... more

Deep learning for faster, more accurate and safer MRI analysis

International pool invests ~ 2 Mio € in medicine start-up mediaire

17-Dec-2020 HTGF, primeCROWD and LIFTT are part of an international round for the development of “Deep learning diagnostic” which allows faster, more accurate and safer MRI analysis. Expansion into European markets will start in 2021 accompanied by a significant expansion of product portfolio  mediaire ... more

New tests identify very early changes in Alzheimer's disease before symptoms appear

07-Dec-2020 Researchers at the University of Gothenburg in Sweden, together with their colleagues at the Barcelona Beta Research Centre in Spain, the University Medical Centre in Ljubljana, Slovenia, and the University of Paris, have found new forms of tau protein that become abnormal in the very early ... more

New butterfly-inspired hydrogen sensor is powered by light

Light-activated sensor delivers precision results at room temperature: For medical applications and hydrogen economy

07-Dec-2020 Inspired by the surface of butterfly wings, researchers have developed a light-activated hydrogen sensor that produces ultra-precise results at room temperature. The technology can detect hydrogen leaks well before they pose safety risks and can measure tiny amounts of the gas on people's b ... more

Detection of cancer from exhaled breath

Breath gas analysis for medical diagnostics

03-Dec-2020 The air we exhale contains information that can assist with the diagnosis of disease. Researchers at the Fraunhofer Project Hub for Microelectronic and Optical Systems for Biomedicine MEOS are now developing solutions designed to enable the analysis of breath gas for this purpose. Although ... more

All news on diagnostics

Leverage the huge potential that lies dormant in the vast amounts of lab data generated daily

Laboratory SaaS provider Labforward closes Series-B

12-Jan-2021 Labforward has closed a new financing round. The laboratory equipment manufacturers Tecan and 2mag as well as existing investor Peppermint Venture Partners are investing more than € 5 million in the laboratory software company with headquarters in Berlin. Laboratories face the challenge of ... more

LABVOLUTION moves from May to September

While preparations for LABVOLUTION 2021 are already well advanced, the trade show for the smart laboratory plays it safe

25-Nov-2020 In September, the current situation will be less critical - this is the opinion of the vast majority of LABVOLUTION exhibitors. Although there would have been an elaborate security concept for the original date in May, the organizers of Deutsche Messe AG are now postponing the trade show fo ... more

analytica China 2020 concludes successfully

More than 1,000 new products point to future trends

24-Nov-2020 analytica China 2020 came to a successful conclusion on November 18, 2020 at the Shanghai New International Expo Centre. The show brought together 1,009 exhibitors (2018: 950) and 112 represented companies and partners. 23,652 professional visitors attended. With six exhibition halls, eight ... more

analytica 2020 with very good results in the digital format

Largest virtual platform of the laboratory industry

27-Oct-2020 analytica 2020 successfully concludes five days of virtual trade fair and presentation formats: A total of 21,641 participants (unique users) from 152 nations took part in the world’s leading trade fair for laboratory technology, analysis and biotechnology, which was held for the first time ... more

Strong profitable growth at Sartorius

Positive development of the Lab Products & Services Division

21-Oct-2020 Sartorius closed the first nine months of 2020 with significant double-digit growth rates in sales revenue and earnings. “In the third quarter, we saw high demand for nearly our entire product range,” said Joachim Kreuzburg, CEO. “On top of overall strong organic growth, additional momentum ... more

analytica Vietnam 2021 postponed from April to October

Exhibitors thus will be able to better plan their trade fair participation

20-Oct-2020 analytica Vietnam, the most important meeting place for the laboratory industry in the country, will be postponed from April 2021 to the autumn and now takes place at the Saigon Exhibition & Convention Center in Ho Chi Minh City from October 7 to 9, 2021. Against the background of the ongoi ... more

analytica 2020: The world’s largest virtual trade fair for analysis, laboratory technology and biotechnology

Market figures: German laboratory industry in the coronavirus year with winners and losers

13-Oct-2020 For the first time in its more than fifty-year-long success story, from October 19 to 23 analytica 2020 will take place in purely digital form. This year, no other format offers such a comprehensive overview of the latest developments in analysis, biotechnology and laboratory technology. 26 ... more

analytica conference 2020 for the first time virtual

Topics in focus: Antibiotic resistance and the “laboratory of the future”

09-Oct-2020 Current questions and approaches in analysis are in the focus of the analytica conference, which will take place from October 19 to 23, 2020, in the context of analytica virtual in a purely digital manner. In 31 sessions, which will be broadcast repeatedly in order to enable participation i ... more

Purification specialist BIA Separations to become part of Sartorius

BIA Separations will be Sartorius’ center of excellence for purification of cell and gene therapeutics

05-Oct-2020 Sartorius announced it has entered into a definitive agreement to merge purification specialist BIA Separations into its subgroup Sartorius Stedim Biotech in a transaction totaling 360 million euros of which 240 million euros will be paid in cash and 120 million euros in Sartorius Stedim Bi ... more

analytica 2020: World’s leading trade fair to be held virtually

analytica virtual to take the place of the presence fair in Munich

02-Sep-2020 This year, Messe München is hosting the world’s leading trade fair for laboratory technology, analysis and biotechnology as a virtual event. The new format analytica virtual will enable exhibitors to book digital trade fair booths for October 19 to 23. Furthermore, it offers all customers a ... more

All news on laborausstattung / laborbedarf

Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates

Company continues Development of Two Investigational Therapeutic Candidates

26-Jan-2021 Merck, known as MSD outside the United States and Canada, announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeut ... more

Distribution of COVID-19 vaccines with delivery drones

Wingcopter raises $22M to advance technology leadership in drone delivery, announces serial production

26-Jan-2021 Wingcopter, the German developer, manufacturer and operator of unmanned delivery drones for commercial and humanitarian applications, has secured $22 million in Series A funding. Wingcopter will use the funds to strengthen its leadership in drone-based logistics, with a special focus on hea ... more

Development of a small molecule that inhibits the replication of SARS-CoV-2 and other RNA viruses

Forbion invests USD 2.3M in seed financing of CoviCept Therapeutics

22-Jan-2021 Forbion, a European life sciences venture capital firm, announces a $2.3m seed investment in newly formed CoviCept Therapeutics, Inc., a California-based company that is developing a small molecule that inhibits the replication of SARS-CoV-2 (COVID-19) and other RNA viruses. CoviCept’s lead ... more

Start-up ViGeneron announces research collaboration with Daiichi Sankyo

Evaluate vgAAV for novel ophthalmic gene therapy

19-Jan-2021 ViGeneron GmbH, a gene therapy company, announced a research collaboration to utilize its novel engineered adeno-associated virus (vgAAV) vectors with Daiichi Sankyo Company, Limited, for delivering a novel therapeutic protein to address an undisclosed target in a highly prevalent ophthalmi ... more

Open Innovation on the rise in medical and pharmaceutical research

18-Jan-2021 The Ludwig Boltzmann Institute Digital Health and Patient Safety has analyzed previously published scientific publications on open innovation in the context of medical and pharmaceutical research. Open innovation (OI) in the context of medical and pharmaceutical research began to appear in ... more

Max Planck director receives science award for production of affordable drugs

Sustainable and affordable: Using plant waste, air and light to produce an active substance against malaria

13-Jan-2021 The American Chemical Society (ACS) has awarded Peter H. Seeberger and two colleagues the "ACS Award for Affordable Green Chemistry" for developing a particularly efficient chemical process for producing artemisinin. All the components needed to produce the active ingredient come from natur ... more

Boehringer Ingelheim and Google Partner for Pharma R&D

Scientists from both companies will be breaking new ground in the application of quantum computing to molecular dynamics simulations

12-Jan-2021 Boehringer Ingelheim announced a collaborative agreement with Google Quantum AI, focusing on researching and implementing cutting-edge use cases for quantum computing in pharmaceutical research and development (R&D), specifically including molecular dynamics simulations. The new partnership ... more

Microreactor for synthesis with Grignard reagents

Continuous process control: faster, safer, cleaner

06-Jan-2021 In 1912, Victor Grignard was awarded the Nobel Prize in Chemistry for his discovery of what came to be known as Grignard reagents. Since then, these compounds have come to play a key role in the chemical and pharmaceutical industries. Now, in a development by Fraunhofer researchers, a new t ... more

ViGeneron and Biogen collaborate

ViGeneron signs global collaboration agreement for ophthalmic gene therapy development

05-Jan-2021 ViGeneron GmbH announced a global collaboration and licensing agreement with Biogen Inc. to develop and commercialize gene therapy products based on adeno-associated virus (AAV) vectors to treat inherited eye diseases. The companies will use ViGeneron’s proprietary vgAAV, novel engineered A ... more

Evotec achieves milestone in its neurodegeneration collaboration with Bristol Myers Squibb

Evotec receive a US$ 6 m payment

05-Jan-2021 Evotec SE announced that the Company has received a US$ 6 m payment from Bristol Myers Squibb Company within the companies’ iPSC-based neuroscience partnership. The payment follows Bristol Myers Squibb’s decision to add another drug discovery project to the partnership’s portfolio. Evotec a ... more

All news on pharma

Fighting Cancer from a Chair

Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

27-Jan-2021 Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum atoms. Unlike cisplatin, this drug also directly inhibits metas ... more

A new mechanism protects against cancer cell migration and neuron hyperexcitability

27-Jan-2021 G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in the journal Cell. The study was led by scientists from the University of Innsbruck and the German Cancer Research C ... more

Scientists use novel ink to 3D-print ‘bone’ with living cells

3D printers may one day become a permanent fixture of the operating theatre

27-Jan-2021 Scientists from UNSW Sydney have developed a ceramic-based ink that may allow surgeons in the future to 3D-print bone parts complete with living cells that could be used to repair damaged bone tissue. Using a 3D-printer that deploys a special ink made up of calcium phosphate, the scientists ... more

Tracing the path of leukemia

Chemical signature of chronic lymphocytic leukemia already present in the precancerous stage

26-Jan-2021 B-cell lymphocytosis, a condition in which individuals have increased levels of particular white blood cells, in some cases leads to blood cancer. As an international team of researchers now shows in samples from patients, both diseases exhibit similar epigenetic signatures that are forming ... more

A treatment for every kind of cancer

Start-up recently received seed funding of USD 30 million with a view to making universal, ready-to-use T cell cancer therapies a reality

26-Jan-2021 Researchers from the University of Basel have identified cells in the immune system that are able to attack a wide range of cancer cells. Through a start-up, they are now aiming to use their discovery to develop clinically applicable treatments that will mark the next milestone in cell-base ... more

Detailed tumour profiling

Better determine which treatment will best match every patient’s cancer and thus be most effective.

25-Jan-2021 As part of a clinical study involving patients from the University Hospitals in Zurich and Basel, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumours. Their goal is to help physicians to better determine which treatm ... more

SARS-CoV-2 attacks the heart

Research team detects biomarkers for cardiovascular stress in the blood of COVID-19 patients

25-Jan-2021 Infections with the SARS-CoV-2 coronavirus are not only a burden on the lungs. The virus also massively affects the cardiovascular system. A research group of the Institute for Molecular and Translational Therapy Strategies of the Hannover Medical School (MHH) has now detected certain bioma ... more

New approach explains how protein complexes regulate cancer genes

New starting point for improved cancer therapies

25-Jan-2021 While NUP98-fusion proteins have been shown to cause leukaemia, the molecular mechanisms have so far been unknown. In a recently published study that was led by Vetmeduni Vienna, researchers have now been able to decipher an important part of these mechanisms. According to the study, a poss ... more

Single-cell test can reveal precisely how drugs kill cancer cells

New method sees how pharmaceuticals induce cancer cell death and how cancer cells adapt

22-Jan-2021 Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D2O-probed CANcer Susceptibility Test Ramanometry (D2O-CANST-R) to see, at si ... more

Blood group co-determines composition of the intestinal microbiome

In a large genome study, a research team demonstrates correlations between certain gene variants and the composition of bacterial colonization in the human body

21-Jan-2021 For several years, scientists worldwide have been investigating the extent to which microorganisms living in and on the human body influence central life processes and thus health and disease. Today they assume that there is a connection between the totality of the microbial colonization in ... more

All news on healthcare
News by department
  • Products

    Merck Discontinues Development of SARS-CoV-2/COVID-19 Vaccine Candidates

    Company continues Development of Two Investigational Therapeutic Candidates

    26-Jan-2021 Merck, known as MSD outside the United States and Canada, announced that the company is discontinuing development of its SARS-CoV-2/COVID-19 vaccine candidates, V590 and V591, and plans to focus its SARS-CoV-2/COVID-19 research strategy and production capabilities on advancing two therapeut ... more

    A treatment for every kind of cancer

    Start-up recently received seed funding of USD 30 million with a view to making universal, ready-to-use T cell cancer therapies a reality

    26-Jan-2021 Researchers from the University of Basel have identified cells in the immune system that are able to attack a wide range of cancer cells. Through a start-up, they are now aiming to use their discovery to develop clinically applicable treatments that will mark the next milestone in cell-base ... more

    New and highly efficient method for SARS-CoV-2 mutation analysis

    Mutations can be assigned directly without any intermediate mathematical steps

    18-Jan-2021 The rapid spread of the newly emerging SARS-CoV-2 virus variant B.1.1.7 in Great Britain and other countries shows, changes in the genome of the SARS-CoV-2 virus can lead to new biological properties.  Most of the approximately 12,000 mutations in the genome of the SARS-CoV-2 virus that hav ... more

  • Business

    Fujifilm to Invest Over 200 Billion yen to Establish New Large-Scale Cell Culture Manufacturing Site for Biopharmaceuticals in the U.S.A.

    End-to-End Single-Site Solution from Drug Substances to Fill-Finish & Packaging

    08-Jan-2021 FUJIFILM Corporation is making an investment of more than 200 Billion yen (2 Billion USD) to establish a new large-scale cell culture production site in the United States to accelerate the growth of its biopharmaceutical contract development and manufacturing business (CDMO). FUJIFILM Diosy ... more

    Merck Acquires AmpTec to Expand mRNA Capabilities for Vaccines, Treatments and Diagnostics

    08-Jan-2021 Merck announced the acquisition of AmpTec, a leading Hamburg, Germany-based, mRNA contract development and manufacturing organization (CDMO). The deal strengthens Merck’s capabilities to develop and manufacture mRNA for its customers for use in vaccines, treatments and diagnostics applicabl ... more

    Sartorius to acquire Novasep’s chromatography process equipment division

    Strengthens Sartorius position in downstream bioprocessing

    07-Jan-2021 The life science company Sartorius announced it has entered into an agreement through its subgroup Sartorius Stedim Biotech to acquire the chromatography process equipment division of Novasep. The parties agreed not to disclose the purchase price until the necessary regulatory approvals hav ... more

  • Price Development

    Are the high prices of cancer drugs justified?

    Does the cost correspond to the particular drug’s effectiveness in combating the disease?

    05-May-2020 Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international UZH study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clin ... more

    Drug costs vary by more than 600% in study of 10 high-income countries

    13-Jun-2017 In a study of 10 high-income countries with universal health care, costs for prescription drugs in 6 of the largest categories of primary care medicines varied by more than 600%. All countries except Canada offered universal coverage of outpatient prescription drugs. The study looked at dat ... more

    Cell Medica granted Orphan Drug designation for novel cellular therapy

    18-Mar-2015 Cell Medica announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to the company’s cancer immunotherapy treatment, referred to as CMD-003, under development for Epstein-Barr Virus (EBV) positive non-Hodgkin lymphomas. Additionally, the company announ ... more

  • Research

    Fighting Cancer from a Chair

    Platinum complex inhibits metastasis through conformational modulation of heparan sulfate

    27-Jan-2021 Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum atoms. Unlike cisplatin, this drug also directly inhibits metas ... more

    A new mechanism protects against cancer cell migration and neuron hyperexcitability

    27-Jan-2021 G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in the journal Cell. The study was led by scientists from the University of Innsbruck and the German Cancer Research C ... more

    Detect neurodegenerative diseases such as Alzheimer's by a simple eye scan?

    Milestone on the way to early diagnostics: Researchers use spectroscopic means to decipher the biochemical composition of the retina

    27-Jan-2021 Diagnosing Alzheimer's disease through a non-invasive eye scan long before symptoms appear: a European research team involving Leibniz IPHT has come one step closer to achieving this goal. Using a laser-based method, the researchers have succeeded in discriminating between healthy and Alzhe ... more

  • People

    Waters Corporation Appoints Pearl S. Huang to Board of Directors

    14-Dec-2020 Waters Corporation announced that Dr. Pearl S. Huang, President and CEO of Cygnal Therapeutics and venture partner at Flagship Pioneering, has been appointed as a Director of Waters Corporation, effective January 1, 2021.  “We are pleased to welcome Pearl to the Waters Board of Directors,” ... more

    CureVac expands management board

    CureVac appoints Antony Blanc as Chief Business Officer and Chief Commercial Officer

    07-Dec-2020 CureVac N.V. announced that Antony Blanc, PhD, was appointed Chief Business Officer and Chief Commercial Officer of CureVac. In this role, he will be responsible for building the network of partnerships that will support the growth of CureVac, for developing the competitiveness and commerci ... more

    Merck: Stefan Oschmann to Hand Over Chair of Executive Board to Belén Garijo in 2021

    Two internationally experienced managers to join Executive Board

    30-Sep-2020 Stefan Oschmann will hand over the Chair of the Executive Board of Merck to Belén Garijo in 2021. The Board of Partners of E. Merck KG has appointed Garijo as new Chair of the Executive Board and CEO of Merck effective May 1, 2021. She is currently Vice Chair of the Executive Board and Depu ... more

  • Finances

    Distribution of COVID-19 vaccines with delivery drones

    Wingcopter raises $22M to advance technology leadership in drone delivery, announces serial production

    26-Jan-2021 Wingcopter, the German developer, manufacturer and operator of unmanned delivery drones for commercial and humanitarian applications, has secured $22 million in Series A funding. Wingcopter will use the funds to strengthen its leadership in drone-based logistics, with a special focus on hea ... more

    New separation technology for biomolecules

    i3 Membrane receives 7 figure sum for development and market launch

    26-Jan-2021 Four investors are financing the further growth of i3 Membrane GmbH. High-tech venture capital investor HTGF from Bonn, Germany, and three private investors are together investing a 7 figure sum in the further development and market launch of new separation technology for biological molecul ... more

    Development of a small molecule that inhibits the replication of SARS-CoV-2 and other RNA viruses

    Forbion invests USD 2.3M in seed financing of CoviCept Therapeutics

    22-Jan-2021 Forbion, a European life sciences venture capital firm, announces a $2.3m seed investment in newly formed CoviCept Therapeutics, Inc., a California-based company that is developing a small molecule that inhibits the replication of SARS-CoV-2 (COVID-19) and other RNA viruses. CoviCept’s lead ... more

  • Cooperation

    Start-up ViGeneron announces research collaboration with Daiichi Sankyo

    Evaluate vgAAV for novel ophthalmic gene therapy

    19-Jan-2021 ViGeneron GmbH, a gene therapy company, announced a research collaboration to utilize its novel engineered adeno-associated virus (vgAAV) vectors with Daiichi Sankyo Company, Limited, for delivering a novel therapeutic protein to address an undisclosed target in a highly prevalent ophthalmi ... more

    Boehringer Ingelheim and Google Partner for Pharma R&D

    Scientists from both companies will be breaking new ground in the application of quantum computing to molecular dynamics simulations

    12-Jan-2021 Boehringer Ingelheim announced a collaborative agreement with Google Quantum AI, focusing on researching and implementing cutting-edge use cases for quantum computing in pharmaceutical research and development (R&D), specifically including molecular dynamics simulations. The new partnership ... more

    ViGeneron and Biogen collaborate

    ViGeneron signs global collaboration agreement for ophthalmic gene therapy development

    05-Jan-2021 ViGeneron GmbH announced a global collaboration and licensing agreement with Biogen Inc. to develop and commercialize gene therapy products based on adeno-associated virus (AAV) vectors to treat inherited eye diseases. The companies will use ViGeneron’s proprietary vgAAV, novel engineered A ... more

  • Technology

    LGC acquires The Native Antigen Company

    Strengthening LGC'S offer to the IVD sector

    10-Jul-2020 LGC announced the acquisition of The Native Antigen Company (NAC), supplier of high quality infectious disease antigens and antibodies. NAC is a developer, manufacturer and supplier of critical reagents to the in vitro diagnostic (IVD), pharmaceutical and academic sectors. It offers a compr ... more

    Domain Therapeutics is granted European and US patent for biosensors assessing GPCR trafficking

    05-Feb-2020 Domain Therapeutics announced that it has been granted a patent in the US and in Europe covering a novel family of biosensors.   The patent, entitled ‘Biosensors for monitoring biomolecule localization and trafficking in cells’, was initially filed by Prof. Michel Bouvier and his team and i ... more

    Printing nanoparticle shapes for medical applications

    18-Apr-2019 Personal drug delivery or nano-robotic systems could be a key concept for future medical applications. In this context, scientists around David Ng (Department of Prof. Tanja Weil) of the Max Planck Institute for Polymer Research (MPI-P) have recently developed a technology to customize the ... more

  • Laws

    Japan and Singapore Grant CRISPR Patents to Merck

    27-Nov-2019 Merck announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide. “Paired nickases represent a significant step in incre ... more

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    Merck Awarded Canadian CRISPR Nickase Patent for Foundational Genome-Editing Technology

    05-Mar-2019 Merck announced that the Canadian Patent Office has allowed Merck’s patent application directed to the use of paired CRISPR nickases in eukaryotic cells. The patent provides an important and more specific solution for scientists who need accurate methods when developing treatments for diffi ... more

  • Market

    M&A in chemicals and life sciences slowed down by global lockdowns

    Race for COVID-19 vaccine

    13-Jul-2020 In the first half of this year, the transaction volume of mergers and acquisitions in the chemical and life sciences industries has decreased dramatically. The volume of deals announced in the first six months is only $84 billion. Compared to the previous year (389 billion dollars), this is ... more

    Many of the deadliest cancers receive the least amount of research funding

    'Embarrassing' or stigmatized cancers like lung and liver are underfunded

    23-Jul-2019 Many of the deadliest or most common cancers get the least amount of nonprofit research funding, according to a new Northwestern Medicine study that examined the distribution of nonprofit research funding in 2015 across cancer types. Colon, endometrial, liver and bile duct, cervical, ovaria ... more

    Gene Editing Tools Gain an Uptick in Sales With Emphasis on Rare Genetic Disorder Management

    22-Jul-2019 According to latest research by FMI, the global gene editing tools market is estimated to have accounted for more than US$ 258 Mn in terms of value in 2018. The report on the gene editing tools market further projects that the gene editing tools market is likely to grow at a CAGR of over 18 ... more

  • Politics

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    ECETOC Task Force provides new insights

    Toxicity testing of microparticles and poorly soluble liquids in the water environment

    15-Jan-2019 A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ... more

    15 emerging technologies that could reduce global catastrophic biological risks

    11-Oct-2018 Strategic investment in 15 promising technologies could help make the world better prepared and equipped to prevent future infectious disease outbreaks from becoming catastrophic events. This subset of emerging technologies and their potential application are the focus of a new report, Tech ... more

  • Manufacturing

    Fujifilm to Invest Over 200 Billion yen to Establish New Large-Scale Cell Culture Manufacturing Site for Biopharmaceuticals in the U.S.A.

    End-to-End Single-Site Solution from Drug Substances to Fill-Finish & Packaging

    08-Jan-2021 FUJIFILM Corporation is making an investment of more than 200 Billion yen (2 Billion USD) to establish a new large-scale cell culture production site in the United States to accelerate the growth of its biopharmaceutical contract development and manufacturing business (CDMO). FUJIFILM Diosy ... more

    KNAUER is expanding its business activities into the field of lipid nanoparticle production equipment

    In connection with the development of mRNA-based vaccines against Corona, LNPs have shown to be a suitable delivery form

    11-Dec-2020 Lipid nanoparticles (LNPs) encapsulate and protect the delicate active ingredient and allow its transport to the target cells in the human body. This will be the first large-scale use of mRNA and lipid nanoparticles in vaccination history. KNAUER, the Berlin based manufacturer of high-tech ... more

    Merck Expands Life Science Production Capacities in the United States

    Global coronavirus pandemic has significantly increased demand

    08-Dec-2020 Merck announced the broadening of its manufacturing footprint with a combined € 40 million investment at its production facilities in Danvers, Massachusetts, and Jaffrey, New Hampshire, USA. These sites supply critical products to customers developing lifesaving therapies, including Covid-1 ... more

  • Career

    Eppendorf with worldwide setting program

    Around 250 vacancies at all locations by the end of 2019

    26-Apr-2019 The Eppendorf Group is creating around 250 new jobs worldwide this year. A large proportion of the new jobs will be created in Hamburg at the headquarters of the globally active life sciences company and is an important component of Eppendorf's growth strategy. "Eppendorf is growing strongl ... more

    Lower pension, shorter life

    12-Apr-2019 Income and social status have an increasing effect on life expectancy in Germany. On average, men with very low retirement pay die five years earlier than those who are much better off. Poverty shortens life. According to a study by researchers at the Max Planck Institute for Demographic Re ... more

    KNAUER among the top one percent of employers in Germany

    28-Feb-2019 In the study "Leading Employers Germany 2019", the Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER was ranked as one of the best employers for the second time. This makes KNAUER one of the companies with the best ratings in an independent meta-study conducted ... more

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