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How the cell protects itself

Researchers discover the mechanism that prevents damage caused by shortened proteins

14-Jun-2019 The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of “spliceosomes”. If this protection does not happen, the entire cell is in danger: meaning that cance ... more

Those who live longer have fewer children

The time between two generations sets the price of fertility

14-Jun-2019 A long life and lots of children – that was quite a common aspiration until not so long ago. But the world of animals reveals that high fertility and longevity are often mutually exclusive: Particularly animals with shorter lifespans are often very fertile while animals that live longer fre ... more

Like a swimming donut

New way of locomotion discovered in single-celled organisms

14-Jun-2019 A research team led by Dr. Sebastian Hess at the University of Cologne discovered that the unicellular microbe Idionectes vortex moves by means of a rotating flagellum. Special about this discovery is the fact that the flagellum bends into a ring and rotates about its internal axis – enabli ... more

Construction kit for custom-designed products

Biotechnologists develop robust and efficient methods for the production of new peptide drugs

13-Jun-2019 Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now succeeded in changing these enzymes so that entirely new natural produ ... more

"Micro-origami": Artificial blood vessels through 4D pressure and molecular self-organization

13-Jun-2019 In the future, it may be possible to produce finely structured blood vessels by printing. The chemist and materials scientist Prof. Dr. Leonid Ionov and a research group at the University of Bayreuth are researching the basis for this. The aim: To structure thin polymer layers in such a way ... more

New vulnerability found in major human viruses

Structural feature may lead to antivirals for the common cold, polio, and other pathogens

13-Jun-2019 Discovery of a new feature of a large class of pathogenic viruses may allow development of new antiviral medications for the common cold, polio, and other illnesses, according to a new study publishing June 11 in the open-access journal PLOS Biology by Rana Abdelnabi and Johan Neyts of the ... more

Learning from Nature’s Bounty: New Libraries for Drug discovery

12-Jun-2019 Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult to emulate and build on Nature’s success in the laboratory. By ... more

Evotec receives $ 23.8 m grant to join the global fight against tuberculosis

12-Jun-2019 Evotec SE announced that the company has entered into a five-year partnership with the Bill & Melinda Gates Foundation to discover new treatment regimens that better address tuberculosis (“TB”), a severe global health burden and one of the leading causes of death due to infectious diseases ... more

How different antibiotics work together

12-Jun-2019 In modern medicine, antibiotics are as important as they are problematic. On the one hand, they are still the only effective treatment option for many diseases; on the other hand, the number of resistant pathogens is on the rise, a situation about which the WHO already raised a serious warn ... more

DNA origami to scale-up molecular motors

12-Jun-2019 Researchers have successfully used DNA origami to make smooth-muscle-like contractions in large networks of molecular motor systems, a discovery which could be applied in molecular robotics."We successfully demonstrated programmed self-assembly of a biomolecular motor system," write the res ... more

All news

Dynamics of key viral attack strategy visible for first time

Visualizing and quantifying frameshifting mechanisms in living cells

11-Jun-2019 Many infectious viruses, from HIV to West Nile, rely on a fundamental biological process called frameshifting to maximize their attack. Long identified as a key mechanism that viruses use to proliferate inside their hosts, the real-time dynamics of frameshifting had never been directly obse ... more

Merck and Rigaku Form Partnership to Develop Novel Molecular Structure Analysis Technology

11-Jun-2019 Merck and Rigaku Corp., Tokyo, Japan, have signed a joint development agreement to develop lab consumables based on crystalline sponge technology, which determines the absolute chemical structure of organic molecules and enables X-ray crystallography without crystallization of the analyte. ... more

Merck Opens Application Phase for Next Accelerator

Startups can apply for programs at Merck headquarters in Darmstadt or in China

07-Jun-2019 Merck announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at ... more

In-situ measurement of 3D protein structure inside living eukaryotic cells

Nuclear magnetic resonance measurement and state-of-the-art computational science reveal protein structures in higher eukaryotic cells

04-Jun-2019 Researchers from Tokyo Metropolitan University have successfully determined the high-resolution three-dimensional structure of proteins inside living eukaryotic cells. They combined "in-cell" nuclear magnetic resonance (NMR) spectroscopy, a bioreactor system and cutting-edge computational a ... more

Detecting bacteria in space

24-May-2019 Scientists at Université de Montréal and McGill University have pioneered and tested a new genomic methodology which reveals a complex bacterial ecosystem at work on the International Space Station. Their study is published today in Environmental Microbiology. Until now, relatively little w ... more

Experimental noninvasive tool monitors effectiveness of stem cell transplantation

24-May-2019 Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive and noninvasive tool to assess the effectiveness of the transplante ... more

Microglia Turned On

Visualizing microglia in brain tissue with a fluorescence turn-on substrate

20-May-2019 Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents. As detaile ... more

Molecular Devices and life science start-up cytena expand their partnership

New CloneSelect Single-Cell Printer products

15-May-2019 Molecular Devices, LLC announced an expansion in its partnership with cytena GmbH to launch the CloneSelect™ Single-Cell Printer™ Series in North America. Building on their success of the CloneSelect™ Single-Cell Printer™ SCP™ system, the new family evolves both the ease of use for image-ba ... more

Early in vitro testing for adverse effects on embryos

15-May-2019 ETH researchers have combined embryonic cells and liver cells in a new cell culture test. This combination lets them detect adverse effects that new medications may have on embryos early on in the drug development process. Medications have to be safe for mothers-to-be and for their unborn c ... more

Gold makes invisible surfaces visible in CT

New method for displaying previously invisible surface details using computer tomography developed

10-May-2019 Today, the three-dimensional visualization and analysis of biological samples using computer tomography (CT) is a routine procedure. However, in the past it was very difficult to visualize the fine surface details of many organisms. Scientists at the Universities of Cologne and Bonn and the ... more

All news on bioanalytics

Construction kit for custom-designed products

Biotechnologists develop robust and efficient methods for the production of new peptide drugs

13-Jun-2019 Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now succeeded in changing these enzymes so that entirely new natural produ ... more

Merck Opens Application Phase for Next Accelerator

Startups can apply for programs at Merck headquarters in Darmstadt or in China

07-Jun-2019 Merck announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at ... more

Evotec and Celgene further expand iPSC collaboration

06-Jun-2019 Evotec SE announced that its strategic alliance with Celgene Corporation (“Celgene”) has been expanded to include a new cell type triggering a payment of $ 9.0 m to Evotec. Evotec and Celgene initiated the collaboration in December 2016 to identify disease-modifying treatments for a broad r ... more

Snapshots of the flu virus replication machine in action

05-Jun-2019 Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, provide valuable information for the next generation of anti-inf ... more

Insight into possible origins of immunological memory

05-Jun-2019 Natural killer cells are part of the innate immune system. Their role is to detect virus-infected cells and destroy them. When an infection is detected, a small subset of the most effective killer cells is identified and selectively expanded – as a team from the Technical University of Muni ... more

Bid to beat superbugs boosted by immune defence discovery

04-Jun-2019 The fight against superbugs could be helped by the discovery of a potential therapy based on the body's natural immune defences. Scientists have found that a molecule produced by the body - called LL-37 - changes the way cells behave when they are invaded by bacteria. The molecule acts like ... more

Carve-out of Lonza Specialty Ingredients will help segment to become a global leader in microbial control

Specialty Ingredients (LSI) will operate independently, but remain a fully owned segment of Lonza Group.

03-Jun-2019 Lonza Group announced its intention to proceed with a carve-out of its Specialty Ingredients segment (LSI). The decision will see the LSI business under independent management, with increased control over its operations and costs. The segment will remain fully owned by Lonza. The company ha ... more

How to quell a cytokine storm: New ways to dampen an overactive immune system

Penn Medicine, University of Leeds findings have implications for new drug targets for lupus, other autoimmune disorders

03-Jun-2019 BRCA--the family of DNA-repair proteins associated with breast, ovarian, prostate, and pancreatic cancers--interacts with a multipart, molecular complex that is also responsible for regulating the immune system. When certain players in this pathway go awry, autoimmune disorders, like lupus, ... more

Self-healing DNA nanostructures

03-Jun-2019 DNA assembled into nanostructures such as tubes and origami-inspired shapes could someday find applications ranging from DNA computers to nanomedicine. However, these intriguing structures don't persist long in biological environments because of enzymes called nucleases that degrade DNA. No ... more

A new mechanism for accessing damaged DNA

03-Jun-2019 UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by the DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA tightly packed in chromatin, where access to DNA damage is rest ... more

All news on biotechnology

How Artificial Intelligence Detects Rare Diseases

11-Jun-2019 Every year, around half a million children worldwide are born with a rare hereditary disease. Obtaining a definitive diagnosis can be difficult and time consuming. In a study of 679 patients with 105 different rare diseases, scientists from the University of Bonn and the Charité - Universit ... more

Harmless computer gaming or already a health risk?

First psychological test developed to understand excessive gaming behaviour that can lead to 'gaming disorder'

06-Jun-2019 The World Health Organisation (WHO) has just recognised gaming disorder as a new type of mental illness associated with extreme cases of uncontrolled gaming behaviour. The official inclusion of 'gaming disorder' and its definition in the WHO disease catalogue offers new possibilities to stu ... more

Experimental noninvasive tool monitors effectiveness of stem cell transplantation

24-May-2019 Stem-cell based therapies to strengthen the heart muscle and treat other diseases are beginning to show promise in human clinical trials. However, other than observing clinical outcomes, lack of a repeatable, time-sensitive and noninvasive tool to assess the effectiveness of the transplante ... more

Blood biopsy: New technique enables detailed genetic analysis of cancer cells

17-May-2019 A new way to cleanly separate out cancer cells from a blood sample enables comprehensive genetic profiling of the cancer cells, which could help doctors target tumors and monitor treatments more effectively. It is a dramatic improvement over current approaches because it also encompasses th ... more

Therapy Optimisation by Analysing the Genome

15-May-2019 The University Hospital Bonn plans to have a stronger focus on pharmacogenetics – thus emphasising the influence of genetic characteristics on the effect of medications. This idea embodies the approach for personalised medicine. To integrate extensive pharmacogenetic analysis into the clini ... more

Mini-centrifuge simplifies study of blood cells

New organ-on-chip possibilities

14-May-2019 The new micro-device for fluid analysis just unveiled in Advanced Functional Materials will enable more tailored experiments in drug development and disease research. It could also transform water contamination testing and medical diagnosis in natural disaster zones, where its low cost, sim ... more

Detecting cancer before it spreads

Patrizia Paterlini-Bréchot named European Inventor Award 2019 finalist

10-May-2019 The European Patent Office (EPO) announces that cancer researcher Patrizia Paterlini-Bréchot has been nominated as one of three finalists for the European Inventor Award 2019 in the category "Research" for developing a blood filtering technology for the early detection of cancer. Her inven ... more

Bacteria causing infections can be detected more rapidly

A fluorescent molecule for screening Gram-positive bacteria

09-May-2019 Two years ago, a group of infants died at the university hospital and it was found to be Gram-negative bacteria that caused their death. The Gram-negative bacteria turn into pink color and Gram-positive bacteria turn into violet color when stained using the Gram stain which is a bacterial s ... more

Screening proteins to expose early signs of illness

Matthias Mann named European Inventor Award 2019 finalist

08-May-2019 The European Patent Office (EPO) announces that German physicist, biochemist and bioinformatician Matthias Mann has been nominated for the European Inventor Award 2019 for developing techniques to screen proteins in bulk for the early detection of disease. Named as one of three finalists in ... more

Detecting pathogens using quantum technology

08-May-2019 Safe diagnoses of diseases, identification of multidrug-resistant germs, detection of beginning epidemics at an early stage or detection of toxins and pathogens in drinking water and food in even the lowest concentrations – these are major challenges and goals of current research programs. ... more

All news on diagnostics

Merck and Rigaku Form Partnership to Develop Novel Molecular Structure Analysis Technology

11-Jun-2019 Merck and Rigaku Corp., Tokyo, Japan, have signed a joint development agreement to develop lab consumables based on crystalline sponge technology, which determines the absolute chemical structure of organic molecules and enables X-ray crystallography without crystallization of the analyte. ... more

Colliding lasers double the energy of proton beams

28-May-2019 Researchers from Sweden’s Chalmers University of Technology and the University of Gothenburg present a new method which can double the energy of a proton beam produced by laser-based particle accelerators. The breakthrough could lead to more compact, cheaper equipment that could be useful f ... more

Lab Notebook learns to communicate with laboratory devices

labfolder acquires cubuslab and becomes Labforward

23-May-2019 labfolder GmbH, a electronic laboratory notebook (ELN, Electronic Lab Notebook) provider, and cubuslab GmbH, a provider of a manufacturer-independent platform for the digital integration of laboratory instruments, today announced their merger. The joint company will operate under the name L ... more

Jülich Research Center wins the first LABVOLUTION AWARD

Saving time and money while at the same time improving efficiency and promoting sustainability – in short, making the lab a better place in which to work

22-May-2019 At the Jülich Research Center (FZ Jülich), the study group "Bioprocesses and Bioanalytics" has developed new processes for the production of metabolites, intermediates and proteins with the aid of microbial systems. R&D projects in industrial biotechnology typically suffer from insufficient ... more

Eppendorf with worldwide setting program

Around 250 vacancies at all locations by the end of 2019

26-Apr-2019 The Eppendorf Group is creating around 250 new jobs worldwide this year. A large proportion of the new jobs will be created in Hamburg at the headquarters of the globally active life sciences company and is an important component of Eppendorf's growth strategy. "Eppendorf is growing strongl ... more

Fraunhofer presents high-speed microscope with intuitive gesture control

25-Apr-2019 The Fraunhofer Institute for Production Technology IPT in Aachen has developed a high-speed microscope for quality control of large-area objects for the semiconductor and electronics industries or for rapid testing of biological samples. The microscope digitizes samples with up to 500 frame ... more

Sartorius starts off fiscal 2019 with a strong first quarter

18-Apr-2019 Sartorius started off fiscal 2019 with substantial double-digit growth in order intake, sales revenue and earnings. Consolidated first-quarter sales revenue rose in constant currencies by 16.8% to 435.7 million  reported: 19.4%); order intake increased 16.6% to 482.8 million euros (reported ... more

Successful restart at Köttermann

15-Apr-2019 After major changes during the last year, the New Year began with a restart for KÖTTERMANN. The assets of the insolvent Köttermann GmbH & Co KG Labortechnik were acquired on December 1, 2018 by the BLOCK® Group, an international leader in clean room solutions. KÖTTERMANN´s business operatio ... more

analytica Vietnam continues to grow in terms of exhibitors, space and visitors

12-Apr-2019 analytica Vietnam 2019, which took place in Ho Chi Minh City from April 3 to 5, provided a twofold cause for celebration: The country's most important industry platform for laboratory technology, analysis, biotechnology and diagnostics, celebrated its tenth anniversary, marking the most suc ... more

Are Drones Coming to Life Science Labs?

Are You Ready for Lab Samples to be Delivered by Drones?

02-Apr-2019 Hudson Robotics, Inc. announced a collaboration with Physical Sciences Inc. (PSI) to bring drone technology to life science laboratories for sample handling. Specifically, microplates containing samples or reagents will be delivered directly to instruments and automated workcells to perform ... more

All news on lab technology

Construction kit for custom-designed products

Biotechnologists develop robust and efficient methods for the production of new peptide drugs

13-Jun-2019 Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now succeeded in changing these enzymes so that entirely new natural produ ... more

Evotec receives $ 23.8 m grant to join the global fight against tuberculosis

12-Jun-2019 Evotec SE announced that the company has entered into a five-year partnership with the Bill & Melinda Gates Foundation to discover new treatment regimens that better address tuberculosis (“TB”), a severe global health burden and one of the leading causes of death due to infectious diseases ... more

Evotec and Celgene further expand iPSC collaboration

06-Jun-2019 Evotec SE announced that its strategic alliance with Celgene Corporation (“Celgene”) has been expanded to include a new cell type triggering a payment of $ 9.0 m to Evotec. Evotec and Celgene initiated the collaboration in December 2016 to identify disease-modifying treatments for a broad r ... more

Snapshots of the flu virus replication machine in action

05-Jun-2019 Researchers from EMBL Grenoble have, for the first time, observed different functional states of the influenza virus polymerase as it is actively transcribing. These results, published in Nature Structural & Molecular Biology, provide valuable information for the next generation of anti-inf ... more

Nordic Nanovector: European Patent Granted for Betalutin or Humalutin in Combination With Anti-CD20 Antibodies for Treating NHL

04-Jun-2019 Nordic Nanovector ASA announces that the European Patent Organisation (EPO) has granted the company's European Patent covering the use of Betalutin® or Humalutin® in combination with anti-CD20 antibodies for the treatment of non-Hodgkin's lymphoma (NHL). The same patent has also been issued ... more

Bid to beat superbugs boosted by immune defence discovery

04-Jun-2019 The fight against superbugs could be helped by the discovery of a potential therapy based on the body's natural immune defences. Scientists have found that a molecule produced by the body - called LL-37 - changes the way cells behave when they are invaded by bacteria. The molecule acts like ... more

Vetter Works Towards a Sustainable Energy Supply

All German sites of the pharmaceutical service provider will be supplied with green electricity moving forward

31-May-2019 Vetter has reached another important milestone regarding sustainability. Beginning immediately, all German sites of the company will be supplied with only CO2 neutral energy from certified renewable energy sources. This action underlines the CDMO’s commitment to climate and environmental pr ... more

Global Strep A vaccine one step closer

Streptococcus genomes reveal potential vaccine targets present in over 20 countries worldwide

31-May-2019 The search for a global Strep A vaccine has narrowed after researchers sequenced the DNA of more than 2000 Group A Streptococcus samples from around the world. Researchers from the Wellcome Sanger Institute, the University of Cambridge, the Peter Doherty Institute for Infection and Immunity ... more

Epigenetic study provides new approaches to combination therapies for aggressive cancers

30-May-2019 Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes. One of the proteins that plays a key role in gene activation is BRD4, a well-characterized "epigenetic reader" that binds to acetylated lysine residues on both histone and ... more

New compound which kills antibiotic-resistant superbugs discovered

A new compound developed by University of Sheffield experts has killed antibiotic resistant gram-negative bacteria, including E. coli, during tests

29-May-2019 A new compound which visualises and kills antibiotic resistant superbugs has been discovered by scientists at the University of Sheffield and Rutherford Appleton Laboratory (RAL). The team, led by Professor Jim Thomas, from the University of Sheffield's Department of Chemistry, is testing n ... more

All news on pharma

How the cell protects itself

Researchers discover the mechanism that prevents damage caused by shortened proteins

14-Jun-2019 The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of “spliceosomes”. If this protection does not happen, the entire cell is in danger: meaning that cance ... more

"Micro-origami": Artificial blood vessels through 4D pressure and molecular self-organization

13-Jun-2019 In the future, it may be possible to produce finely structured blood vessels by printing. The chemist and materials scientist Prof. Dr. Leonid Ionov and a research group at the University of Bayreuth are researching the basis for this. The aim: To structure thin polymer layers in such a way ... more

New vulnerability found in major human viruses

Structural feature may lead to antivirals for the common cold, polio, and other pathogens

13-Jun-2019 Discovery of a new feature of a large class of pathogenic viruses may allow development of new antiviral medications for the common cold, polio, and other illnesses, according to a new study publishing June 11 in the open-access journal PLOS Biology by Rana Abdelnabi and Johan Neyts of the ... more

Learning from Nature’s Bounty: New Libraries for Drug discovery

12-Jun-2019 Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult to emulate and build on Nature’s success in the laboratory. By ... more

How different antibiotics work together

12-Jun-2019 In modern medicine, antibiotics are as important as they are problematic. On the one hand, they are still the only effective treatment option for many diseases; on the other hand, the number of resistant pathogens is on the rise, a situation about which the WHO already raised a serious warn ... more

Approved medications – new role in combating infections?

07-Jun-2019 Influenza A viruses periodically cause severe influenza epidemics. Due to their genetic variability, new subtypes can emerge that are no longer covered by seasonal influenza vaccines. Looking for an effective treatment of such serious influenza infections, researchers of the Paul-Ehrlich-In ... more

Breaking down pathological protein aggregates

07-Jun-2019 ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson’s and other neurodegenerative diseases. This new finding might provide the basis for new therapeutic approaches. Aggregates of the ... more

Killing the Unkillable Cancer Cells

06-Jun-2019 We all know someone affected by the battle against cancer. And we know that treatments can be quite efficient at shrinking the tumor but too often, they can’t kill all the cells, and so it may come back. With some aggressive types of cancer, the problem is so great that there is very little ... more

Harmless computer gaming or already a health risk?

First psychological test developed to understand excessive gaming behaviour that can lead to 'gaming disorder'

06-Jun-2019 The World Health Organisation (WHO) has just recognised gaming disorder as a new type of mental illness associated with extreme cases of uncontrolled gaming behaviour. The official inclusion of 'gaming disorder' and its definition in the WHO disease catalogue offers new possibilities to stu ... more

Six fingers per hand

A congenital additional finger brings motor advantages

05-Jun-2019 Polydactyly is the extraordinary condition of someone being born with more than five fingers or toes. In a case study published in Nature Communications, researchers from the University of Freiburg, Imperial College London, the University Hospital of Lausanne, and EPFL have for the first ti ... more

All news on healthcare
News by department
  • Products

    Nordic Nanovector: European Patent Granted for Betalutin or Humalutin in Combination With Anti-CD20 Antibodies for Treating NHL

    04-Jun-2019 Nordic Nanovector ASA announces that the European Patent Organisation (EPO) has granted the company's European Patent covering the use of Betalutin® or Humalutin® in combination with anti-CD20 antibodies for the treatment of non-Hodgkin's lymphoma (NHL). The same patent has also been issued ... more

    Merck and Pfizer receive FDA approval for kidney cancer therapy

    BAVENCIO® (avelumab) plus Axitinib Combination for Patients with Advanced Renal Cell Carcinoma

    15-May-2019 Merck and Pfizer Inc. announced that the US Food and Drug Administration (FDA) has approved BAVENCIO® (avelumab) in combination with axitinib for the first-line treatment of patients with advanced renal cell carcinoma (RCC). This is the first FDA approval for an anti-PD-L1 therapy as part o ... more

    Development of an Efficient Enantioselective Desymmetrization Strategy Using Recombinant Pig Liver Esterases

    14-May-2019 An economically significant process intensification for the efficient enzymatic synthesis of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid was achieved by a careful adaption of the reaction mode to minimize mass transfer limitations. (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene ... more

  • Business

    Merck Opens Application Phase for Next Accelerator

    Startups can apply for programs at Merck headquarters in Darmstadt or in China

    07-Jun-2019 Merck announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at ... more

    Carve-out of Lonza Specialty Ingredients will help segment to become a global leader in microbial control

    Specialty Ingredients (LSI) will operate independently, but remain a fully owned segment of Lonza Group.

    03-Jun-2019 Lonza Group announced its intention to proceed with a carve-out of its Specialty Ingredients segment (LSI). The decision will see the LSI business under independent management, with increased control over its operations and costs. The segment will remain fully owned by Lonza. The company ha ... more

    Lab Notebook learns to communicate with laboratory devices

    labfolder acquires cubuslab and becomes Labforward

    23-May-2019 labfolder GmbH, a electronic laboratory notebook (ELN, Electronic Lab Notebook) provider, and cubuslab GmbH, a provider of a manufacturer-independent platform for the digital integration of laboratory instruments, today announced their merger. The joint company will operate under the name L ... more

  • Price Development

    Drug costs vary by more than 600% in study of 10 high-income countries

    13-Jun-2017 In a study of 10 high-income countries with universal health care, costs for prescription drugs in 6 of the largest categories of primary care medicines varied by more than 600%. All countries except Canada offered universal coverage of outpatient prescription drugs. The study looked at dat ... more

    Cell Medica granted Orphan Drug designation for novel cellular therapy

    18-Mar-2015 Cell Medica announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to the company’s cancer immunotherapy treatment, referred to as CMD-003, under development for Epstein-Barr Virus (EBV) positive non-Hodgkin lymphomas. Additionally, the company announ ... more

    BASF increases prices for Vitamin E and A feed grade

    14-Nov-2013 BASF increases prices for Vitamin E and A products for animal nutrition globally and with immediate effect. Prices will increase by 15% for all Vitamin E products and by 10% for all Vitamin A products. Existing contractual obligations with customers will be honored. more

  • Research

    How the cell protects itself

    Researchers discover the mechanism that prevents damage caused by shortened proteins

    14-Jun-2019 The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of “spliceosomes”. If this protection does not happen, the entire cell is in danger: meaning that cance ... more

    Those who live longer have fewer children

    The time between two generations sets the price of fertility

    14-Jun-2019 A long life and lots of children – that was quite a common aspiration until not so long ago. But the world of animals reveals that high fertility and longevity are often mutually exclusive: Particularly animals with shorter lifespans are often very fertile while animals that live longer fre ... more

    Like a swimming donut

    New way of locomotion discovered in single-celled organisms

    14-Jun-2019 A research team led by Dr. Sebastian Hess at the University of Cologne discovered that the unicellular microbe Idionectes vortex moves by means of a rotating flagellum. Special about this discovery is the fact that the flagellum bends into a ring and rotates about its internal axis – enabli ... more

  • People

    Merck Announces Two New Appointments to Group Leadership Positions

    29-May-2019 Merck announced two new appointments to Group leadership positions that will take effect on July 1. Tina Sandmann will become Head of Internal Auditing. She will report to Stefan Oschmann, Chairman of the Executive Board and CEO of Merck. Sandmann succeeds Barbara Weiland, who will become C ... more

    Tomas Blomquist: New CEO & President of Biotage

    28-May-2019 Biotage has appointed Tomas Blomquist as the new CEO and President of Biotage AB. Tomas Blomquist, most recently Vice President EMEA Cardimetabolic at Abbott, will start his assignment on November 6, 2019, and will then take over the responsibility for the Biotage group and its + 400 employ ... more

    Detecting cancer before it spreads

    Patrizia Paterlini-Bréchot named European Inventor Award 2019 finalist

    10-May-2019 The European Patent Office (EPO) announces that cancer researcher Patrizia Paterlini-Bréchot has been nominated as one of three finalists for the European Inventor Award 2019 in the category "Research" for developing a blood filtering technology for the early detection of cancer. Her inven ... more

  • Finances

    NAVAN Closes Seed Funding Round

    Investors include Amgen Ventures, HTGF and Hemi Ventures

    17-May-2019 NAVAN Technologies, Inc., a privately-held biotechnology company enabling the development of next generation cell and gene therapies through its novel, non-viral NanoStraw platform, announced it had closed a seed investment round led by Amgen Ventures, High-Tech Gründerfonds (HTGF), Hemi Ve ... more

    Merck Confirms Forecast for Organic Performance in 2019

    Business in Asia drives Group organic growth

    14-May-2019 Merck significantly increased net sales in the first quarter of 2019, primarily on an organic basis. By contrast, EBITDA pre saw a slight organic decline and was adversely impacted by the absence of positive one-time effects from the previous year. Merck confirmed its full-year forecast for ... more

    ZEISS Innovations Help Achieve Strong Growth

    08-May-2019 The ZEISS Group had a successful end to the first six months of fiscal year 2018/19 (ended 31 March 2019) and saw its revenue rise by 9 percent to EUR 3.019 billion (1st six months of 2017/18: EUR 2.773 billion). 90 percent of this sum was generated by markets outside Germany. At EUR 443 mi ... more

  • Cooperation

    Evotec receives $ 23.8 m grant to join the global fight against tuberculosis

    12-Jun-2019 Evotec SE announced that the company has entered into a five-year partnership with the Bill & Melinda Gates Foundation to discover new treatment regimens that better address tuberculosis (“TB”), a severe global health burden and one of the leading causes of death due to infectious diseases ... more

    Merck and Rigaku Form Partnership to Develop Novel Molecular Structure Analysis Technology

    11-Jun-2019 Merck and Rigaku Corp., Tokyo, Japan, have signed a joint development agreement to develop lab consumables based on crystalline sponge technology, which determines the absolute chemical structure of organic molecules and enables X-ray crystallography without crystallization of the analyte. ... more

    Evotec and Celgene further expand iPSC collaboration

    06-Jun-2019 Evotec SE announced that its strategic alliance with Celgene Corporation (“Celgene”) has been expanded to include a new cell type triggering a payment of $ 9.0 m to Evotec. Evotec and Celgene initiated the collaboration in December 2016 to identify disease-modifying treatments for a broad r ... more

  • Technology

    Printing nanoparticle shapes for medical applications

    18-Apr-2019 Personal drug delivery or nano-robotic systems could be a key concept for future medical applications. In this context, scientists around David Ng (Department of Prof. Tanja Weil) of the Max Planck Institute for Polymer Research (MPI-P) have recently developed a technology to customize the ... more

    BioMCN to produce renewable methanol with green hydrogen

    27-Feb-2019 Nouryon (formerly AkzoNobel Specialty Chemicals) and Gasunie have agreed to supply green hydrogen to BioMCN for the production of renewable methanol from CO2. The companies say it marks the next step in the sustainability of processes in the industry. Nouryon and Gasunie are currently inves ... more

    Growth factors in single cells counted for the first time

    26-Feb-2019 Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die--a process known as apoptosis. When growth factor ... more

  • Laws

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    Merck Awarded Canadian CRISPR Nickase Patent for Foundational Genome-Editing Technology

    05-Mar-2019 Merck announced that the Canadian Patent Office has allowed Merck’s patent application directed to the use of paired CRISPR nickases in eukaryotic cells. The patent provides an important and more specific solution for scientists who need accurate methods when developing treatments for diffi ... more

    ECETOC Task Force provides new insights

    Toxicity testing of microparticles and poorly soluble liquids in the water environment

    15-Jan-2019 A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ... more

  • Market

    Merck announces the winners of its Advance Biotech Grant program

    Merck Awards Grants to Biotechs Focused on Traumatic Brain Injury, Vaccine Development and Chronic Pain

    31-May-2019 Merck announced the winners of its Advance Biotech Grant program in North America during its Biotech Start-up Summit at the Cambridge Innovation Center (Massachusetts, U.S.). The grant is given to small- and mid-size biotechnology companies that need funding and expertise to get their thera ... more

    Lonza to Establish Strategic Biomanufacturing Base in China

    13-Dec-2018 Lonza announced an agreement with GE Healthcare under which GE Healthcare will deliver a biologics facility to Lonza in Guangzhou (CN). As the facility is part of a larger biomanufacturing initiative between GE Healthcare and Guangzhou Development District (GDD), the agreement will be final ... more

    SOPAT GmbH and Malvern Panalytical announce a distribution agreement for US market

    09-Oct-2018 SOPAT GmbH announced a distribution agreement with Malvern Panalytical. Malvern Panalytical is now the exclusive distributor for a complete range of SOPAT photo-optical image analysis instrumentation and software in the United States of America. “We are thrilled to be working together with ... more

  • Politics

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    ECETOC Task Force provides new insights

    Toxicity testing of microparticles and poorly soluble liquids in the water environment

    15-Jan-2019 A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ... more

    15 emerging technologies that could reduce global catastrophic biological risks

    11-Oct-2018 Strategic investment in 15 promising technologies could help make the world better prepared and equipped to prevent future infectious disease outbreaks from becoming catastrophic events. This subset of emerging technologies and their potential application are the focus of a new report, Tech ... more

  • Manufacturing

    Vetter Works Towards a Sustainable Energy Supply

    All German sites of the pharmaceutical service provider will be supplied with green electricity moving forward

    31-May-2019 Vetter has reached another important milestone regarding sustainability. Beginning immediately, all German sites of the company will be supplied with only CO2 neutral energy from certified renewable energy sources. This action underlines the CDMO’s commitment to climate and environmental pr ... more

    Thermo Fisher Scientific to Invest $50 Million to Expand Bioproduction Capabilities

    22-May-2019 Thermo Fisher Scientific Inc. announced that it is investing more than $50 million in its global bioproduction capabilities to provide additional capacity for manufacturing single-use bioprocess container (BPC) systems. Thermo Fisher's single-use technologies are used for critical, sterile ... more

    Merck Invests in Expansion of Manufacturing Capacity for Biotech Medicines

    €150 million investment over the 2019-2023 period in manufacturing site at Aubonne, Switzerland

    28-Mar-2019 Merck announced an investment of €150 million (165 million Swiss francs) in its manufacturing site at Aubonne, Switzerland, to expand manufacturing capacity for its biotech medicines. The investment will cover a new building dedicated to Merck biotech medicines destined for more than 150 co ... more

  • Career

    Eppendorf with worldwide setting program

    Around 250 vacancies at all locations by the end of 2019

    26-Apr-2019 The Eppendorf Group is creating around 250 new jobs worldwide this year. A large proportion of the new jobs will be created in Hamburg at the headquarters of the globally active life sciences company and is an important component of Eppendorf's growth strategy. "Eppendorf is growing strongl ... more

    Lower pension, shorter life

    12-Apr-2019 Income and social status have an increasing effect on life expectancy in Germany. On average, men with very low retirement pay die five years earlier than those who are much better off. Poverty shortens life. According to a study by researchers at the Max Planck Institute for Demographic Re ... more

    KNAUER among the top one percent of employers in Germany

    28-Feb-2019 In the study "Leading Employers Germany 2019", the Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER was ranked as one of the best employers for the second time. This makes KNAUER one of the companies with the best ratings in an independent meta-study conducted ... more

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