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What happens in brain cells affected by Alzheimer’s disease?

Studies on tissue from patients and mini-brains made from stem cells shed light on the disease

15-Jun-2021 In addition to plaques that accumulate outside of nerve cells in the brain, Alzheimer’s disease is also characterised by changes inside these cells. Researchers from the Cell Signalling research group at the Chair of Molecular Biochemistry at RUB, headed by Dr. Thorsten Müller, have been st ... more

Hope in the fight against cancer: They build proteins that are not known to nature

Basel-​based biotech startup has big ideas for the future: it aims to take protein engineering into a new era

15-Jun-2021 Using chemical synthesis, Bright Peak Therapeutics can produce proteins that have never before existed. This holds great potential for cancer immunotherapy. The Basel-​based spin-​off has its beginnings at ETH Zurich. Jeffrey Bode’s long, bold journey began over an after-​work beer in Tokyo ... more

Researchers turned transparent calcite into artificial gold

Breakthrough in metamaterials: New material can serve as a platform for innovative cancer treatments

15-Jun-2021 For the first time in the world, researchers at Tel Aviv University developed an innovative nanotechnology that transforms a transparent calcite nanoparticle into a sparkling gold-like particle. In other words, they turned the transparent particle into a particle that is visible despite its ... more

COVID-19 can cause severe inflammation in the brain

Various immune cells in the brainstem cause formation of inflammatory nodules

15-Jun-2021 Both during and after infection with the Coronavirus SARS-CoV-2, patients may suffer from severe neurological symptoms, including “anosmia”, the loss of taste and smell typically associated with COVID-19. Along with direct damage caused by the virus, researchers suspect a role for excessive ... more

Understanding the evolution of viruses

Key step in the evolutionary history of viruses in a laboratory experiment recreated

14-Jun-2021 Viruses have always had a major influence on life. They emerged a few billion years ago, precisely when is difficult to estimate. There are also several theories as to how viruses originated. While exploring one possibility, researchers at ETH Zurich have managed to recapitulate a potential ... more

Why heart patients should avoid cream cake

Study examines the influence of rumensic acid on heart muscle fibers

14-Jun-2021 Cardiovascular diseases are the most common cause of death in Germany. Important triggers for this are stress, lack of exercise and an unhealthy diet. Now a research team led by Professor Dr. Dietmar Manstein, Director of the Institute of Biophysical Chemistry at Hannover Medical School (MH ... more

A Trojan horse against tuberculosis

New transport route for antibiotics directly into infected cells

14-Jun-2021 Tuberculosis is still the infectious disease that is responsible for the highest number of deaths worldwide. It is caused by Mycobacterium tuberculosis, a bacterium that infects cells in the lungs. There, the pathogen is hardly accessible to most antibiotics. In addition, resistance to exis ... more

Bacteria serves tasty solution to global plastic crisis

Scientists have devised a novel way of tackling the mounting issue of plastic pollution -- by using bacteria to transform plastic waste into vanilla flavoring

14-Jun-2021 Researchers have discovered that the common bacteria E. coli can be deployed as a sustainable way to convert post-consumer plastic into vanillin, a new study reveals. Vanillin is the primary component of extracted vanilla beans and is responsible for the characteristic taste and smell of va ... more

TTP Group opens Pharmaplan branch near Lonza AG in Visp, CH

11-Jun-2021 In response to the investment boom in the pharmaceutical industry, TTP Group is opening another Pharmaplan branch in Switzerland in the third quarter of 2021. With the new subsidiary at the biotech site in Visp, Pharmaplan is meeting the growing global demand for pharmaceutical engineering ... more

Evonik to market and develop new drug delivery platform for mRNA and gene therapy

Evonik and Stanford University sign research collaboration

11-Jun-2021 Evonik is working with Stanford University on a technology to deliver mRNA to tissues and organs that goes beyond the capabilities of lipid nanoparticles (LNPs). This polymer-based platform complements Evonik’s existing portfolio of lipid-based drug delivery, including LNPs. Starting this m ... more

All news

Clever biomolecular labelling enables identification of immune cells

New strategy for labelling peptides

09-Jun-2021 Biomolecules regulate the biological functions inside every living cell. If scientists can understand the molecular mechanisms of such functions, then it is possible to detect severe dysfunction which can lead to illness. At a molecular level, this can be achieved with fluorescent markers t ... more

The Cut and Restore Protein Trick: Self-Excising Designer Proteins Report Isoform Expression

07-Jun-2021 Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at Helmholtz Zentrum München and the Technical University of Munich now ... more

Scientists develop “scifi-RNA-seq” method for ultra-high-throughput RNA sequencing in single cells

An efficient high-throughput method with a wide range of applications

02-Jun-2021 Molecular analysis of single cells provides an important basis for precision medicine. Five years ago, scientists around the world came together to pursue the “Human Cell Atlas” project, with the aim of cataloging all cells in the human body. These data have helped, for example, to identify ... more

New Biochip Technology for Pharma Research

Reliable standard for tissue samples

28-May-2021 In pharmaceutical research, small tissue spheres are used as mini-organ models for reproducible tests. TU Wien has found a way to develop a reliable standard for these tissue samples. Before drugs are tested in clinical trials, they must be tested either by animal experiments or, more recen ... more

What the new pangenome reveals about bovine genes

New genes and functionalities discovered

28-May-2021 When researchers at ETH Zurich compared the reference genomes between several breeds of domestic cattle and closely related wild cattle, they discovered genes with previously unknown functions. Modern genetic research often works with what are known as reference genomes. Such a genome compr ... more

Researchers investigate structural changes in snap-frozen proteins

A novel method allows visualization of molecular motions lasting a few millionths of a second

03-May-2021 Researchers at the University of Bonn and the research center caesar have succeeded in ultra-fast freezing proteins after a precisely defined period of time. They were able to follow structural changes on the microsecond time scale and with sub-nanometer precision. Owing to its high spatial ... more

A new era of genome sequencing

16 new high-quality reference genomes from vertebrates

30-Apr-2021 The international Vertebrate Genomes Project (VGP) publishes their flagship study focused on genome assembly quality and standardization for the field of genomics in a special issue of Nature, along with 20 associated publications. This study presents 16 diploid high-quality, near error-fre ... more

The First Comprehensive Single-Cell Atlas of Human Teeth

The dental pulp and periodontium are susceptible to caries and periodontitis and contain stem cells that have great regenerative potential

29-Apr-2021 Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings open up new avenues for cell-based dental therapeutic approach ... more

A multidimensional view of the coronavirus

Covid-19: analysis of protein interactions as a route to new drugs

20-Apr-2021 What exactly happens when the corona virus SARS-CoV-2 infects a cell? In an article published in Nature, a team from the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry paints a comprehensive picture of the viral infection process. For the first time, the i ... more

Aviation safety: Rapid test for harmful microbes in kerosene developed

Faster and more robust than a PCR test

12-Apr-2021 Fuels such as kerosene or diesel can be contaminated by fungi or bacteria. The microorganisms settle in the liquid itself, on the inner walls of tanks and pipes or in fuel filters and feed on carbon atoms. Since the fungi and bacteria multiply well in this environment, they can form a strea ... more

All news on bioanalytics

Hope in the fight against cancer: They build proteins that are not known to nature

Basel-​based biotech startup has big ideas for the future: it aims to take protein engineering into a new era

15-Jun-2021 Using chemical synthesis, Bright Peak Therapeutics can produce proteins that have never before existed. This holds great potential for cancer immunotherapy. The Basel-​based spin-​off has its beginnings at ETH Zurich. Jeffrey Bode’s long, bold journey began over an after-​work beer in Tokyo ... more

Bacteria serves tasty solution to global plastic crisis

Scientists have devised a novel way of tackling the mounting issue of plastic pollution -- by using bacteria to transform plastic waste into vanilla flavoring

14-Jun-2021 Researchers have discovered that the common bacteria E. coli can be deployed as a sustainable way to convert post-consumer plastic into vanillin, a new study reveals. Vanillin is the primary component of extracted vanilla beans and is responsible for the characteristic taste and smell of va ... more

Evonik to market and develop new drug delivery platform for mRNA and gene therapy

Evonik and Stanford University sign research collaboration

11-Jun-2021 Evonik is working with Stanford University on a technology to deliver mRNA to tissues and organs that goes beyond the capabilities of lipid nanoparticles (LNPs). This polymer-based platform complements Evonik’s existing portfolio of lipid-based drug delivery, including LNPs. Starting this m ... more

Efficiently "switching on" bacteria to produce high-value chemicals

Researchers have found a cheap way to switch bacteria into chemical production mode

10-Jun-2021 High-value chemicals used in biofuels and pharmaceuticals can be made from bacteria by switching their chemistry to produce novel products. Researchers from the University of Warwick have found a way to drastically cut the cost of turning on these switches.We use chemicals for almost everyt ... more

Targeted drug delivery without the normal side effects

Indo-Irish Biotech Startup Secures Funding to Accelerate Cancer and Rare Genetic Disease Therapy

09-Jun-2021 CyGenica has announced that it has raised USD $1.4 million in a seed fund investment round, led by global venture capital investor SOSV. The funding round will accelerate validation of CyGenica’s proprietary technology which enables safe, targeted and affordable intercellular drug delivery. ... more

The biodegradable battery - an ecological miracle

New mini-capacitor consists of carbon, cellulose, glycerin and table salt

07-Jun-2021 The number of data-transmitting microdevices, for instance in packaging and transport logistics, will increase sharply in the coming years. All these devices need energy, but the amount of batteries would have a major impact on the environment. Empa researchers have developed a biodegradabl ... more

The Cut and Restore Protein Trick: Self-Excising Designer Proteins Report Isoform Expression

07-Jun-2021 Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at Helmholtz Zentrum München and the Technical University of Munich now ... more

Enzymes successfully embedded in plastics

Self-cleaning plastics are just the beginning - The potentials this creates are enormous

03-Jun-2021 In general, plastics are processed at way over a hundred degrees Celsius. Enzymes, by contrast, cannot usually withstand these high temperatures. Researchers at the Fraunhofer Institute for Applied Polymer Research IAP have managed to reconcile these contradictions: They are able to embed e ... more

Origin.Bio secures $15 million funding to help manufacturers create a more sustainable future

Start-up connects bioengineers with nature to hack entirely new organisms, freeing manufacturers from petrochemical dependency

02-Jun-2021 Origin.Bio-- a synthetic biology company that replicates and improves ingredients from traditional chemical industrialisation processes, freeing manufacturers from petrochemical dependency -- today announces a $15m funding round led by EQT Ventures. Existing investor BlueYard Capital also p ... more

Recruiting bacteria to build catalysts atom by atom

An enigmatic bacterium proves a useful ally for the synthesis of single-atom catalysts to split hydrogen from water

02-Jun-2021 Exploiting the unusual metal-reducing ability of the iron-breathing bacterium Geobacter sulfurreducens, KAUST researchers have demonstrated a cheap and reliable way to synthesize highly active single-atom catalysts. The innovation, which could dramatically improve the efficiency and cost of ... more

All news on biotechnology

Diagnoses with Deepflash

Microscopic images of tissue sections can now be analyzed much more easily

11-Jun-2021 Information technology can make life easier in many areas – including research. In medicine, for example, it is still standard practice to evaluate microscopy images of tissue sections by hand. This is used, for example, to assess how many cancer cells are in a lymph node. "You often sit in ... more

COVID-19 testing method gives results within one second

Superfast, portable COVID-19 testing method detects the virus much faster than currently available methods

20-May-2021 The COVID-19 pandemic made it clear technological innovations were urgently needed to detect, treat, and prevent the SARS-CoV-2 virus. A year and a half into this epidemic, waves of successive outbreaks and the dire need for new medical solutions -- especially testing -- continue to exist. ... more

PerkinElmer to Acquire In-Vitro Diagnostics Company

Endocrinology testing specialist expands PerkinElmer’s immunodiagnostics segment

19-May-2021 PerkinElmer, Inc. and Immunodiagnostic Systems Holdings PLC (IDS) announced that they have reached an agreement on the terms of a recommended all cash offer whereby PerkinElmer will acquire IDS for approximately $155 million (£110 Million). The transaction has a total enterprise value of ap ... more

Training bees to smell the coronavirus

A trained bee can detect an infected sample within a few seconds

12-May-2021 Start-up InsectSense and Wageningen Bioveterinary Research have trained bees to extend their tongues when they smell the coronavirus. The coronavirus, like other diseases, causes metabolic changes in the body that causes a smell. Bees can be trained within minutes to recognize the scent of ... more

Simple to use device rapidly detects infectious diseases

Marco Donolato and team named European Inventor Award 2021 finalists

12-May-2021 The European Patent Office (EPO) announces that Italian engineer Marco Donolato and team have been nominated as finalists in the "Research" category of the European Inventor Award 2021 for their novel testing device which detects infectious diseases within minutes, enabling medical staff to ... more

Biomarker Detects Severe COVID-19 Early On

SARS-CoV-2-specific immune signature deciphered

10-May-2021 Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help to improve the treatment of severe cases of COVID-19. Most people ... more

osteolabs establishes UK presence

Early detection of osteoporosis

03-May-2021 osteolabs GmbH announces the formation of osteolabs UK Limited in Marlow near London. osteolabs UK is a Joint Venture between osteolabs GmbH as majority shareholder and Christopher Brain, an experienced Medtech business professional with a track record of well over 15 years with some leadin ... more

CRISPR discovery paves the way for novel COVID testing method

LEOPARD has the potential to revolutionize diagnostics

29-Apr-2021 Am I infected with SARS-CoV-2? Is it one of the dangerous variants? Being able to answer these and more questions with a single efficient diagnostic test can be decisive for gauging the spread of disease and selecting the right therapy. In a study published in the journal "Science", researc ... more

A new way of rapidly counting and identifying viruses

A Lancaster University professor has introduced a new concept for rapidly analysing for the presence of a virus from colds to coronaviruses

28-Apr-2021 Based on analysing chemical elements the methodology, which has been adapted from an analytical technique used to identify metallic nanoparticles, is able to detect the presence of viruses within just 20 seconds. Although the tests would need to be performed in a lab, it could be used to qu ... more

oncgnostics cooperates with the Medical University of Graz

Study on Head-and-Neck tumors aims to demonstrate that a diagnostic method can reliably and early detect malignant tumors using non-invasive saliva samples

23-Apr-2021 The biotechnology company oncgnostics GmbH is researching a method for diagnosing Head-and-Neck tumors together with the clinical department for general ENT at the Medical University of Graz as part of the “OroCa-Graz” study. 550,000 people worldwide develop carcinomas of this type every ye ... more

All news on diagnostics

Remote-controlled labs - Lab of the future is liberating scientists from the limitations of their location

California-based startup Strateos closes $56 Million Series B financing

10-Jun-2021 Strateos, Inc., a pioneer in the development of remote access laboratories and lab control software for life science research, announced the closing of its $56.1 million Series B financing led by DCVC and Lux Capital with participation from new investors including Eli Lilly and Company, All ... more

An AI Robot for Pipetting

Researchers from the University of Freiburg have received an EXIST grant for their goodBot startup

31-May-2021 Pipettes are important tools for scientists when transporting liquids in medical, pharmaceutical, biology, and chemistry laboratories. Using pipettes precisely is especially important when repeating experiments. The University of Freiburg researchers Julius Wiener, Tobias Zundel, and Oliver ... more

PerkinElmer to Acquire Nexcelom Bioscience

14-May-2021 PerkinElmer, Inc. announced it has entered into an agreement to acquire Nexcelom Bioscience for $260 Million in cash. The transaction is expected to close during the second quarter of 2021.Nexcelom is a global provider of automated cell counting instruments, image cytometry workstations, as ... more

Eppendorf achieves record revenue and best result in the company’s history in 2020

Revenue rises by 20.3% to €967.2 million in 2020

06-May-2021 In fiscal year 2020, Eppendorf AG succeeded in posting record revenue of €967 million (prior year: €804 million) – a significant year-on-year increase of 20.3% (prior year: 10.2%). EBIT likewise saw a sharp rise of €73.5 million to €217.7 million (prior year: €144.2 million), representing a ... more

New dimension for efficient laboratory work

Laboratory SaaS provider Labforward ramps up Series B financing to >€8.5 million in second closing

06-May-2021 With the successful completion of a second closing, Labforward adds >€3m to the Series B from January, bringing the total funds raised to >€8.5m. The majority of the new investment comes from the Fielmann Family Office, majority owner of the leading German family business of the same name t ... more

Lab supplies out of the 3D printer

LAUDA invests in Better Basics start-up

18-Mar-2021 LAUDA will cooperate with Better Basics Laborbedarf GmbH (BBL). The Dresden-based company, founded in 2019, develops, manufactures and sells smart basic equipment for laboratories that simplifies the organization of laboratory workstations and supports laboratory employees in their daily wo ... more

Sartorius closes 2020 with strong growth

Group management raises sales target for 2025 to about 5 billion euros

29-Jan-2021 Sartorius recorded high growth according to preliminary figures in 2020 due to strong organic development, several acquisitions and the additional momentum from business related to the coronavirus pandemic. The Group closed the year with significant double-digit growth rates in sales revenu ... more

Leverage the huge potential that lies dormant in the vast amounts of lab data generated daily

Laboratory SaaS provider Labforward closes Series-B

12-Jan-2021 Labforward has closed a new financing round. The laboratory equipment manufacturers Tecan and 2mag as well as existing investor Peppermint Venture Partners are investing more than € 5 million in the laboratory software company with headquarters in Berlin. Laboratories face the challenge of ... more

LABVOLUTION moves from May to September

While preparations for LABVOLUTION 2021 are already well advanced, the trade show for the smart laboratory plays it safe

25-Nov-2020 In September, the current situation will be less critical - this is the opinion of the vast majority of LABVOLUTION exhibitors. Although there would have been an elaborate security concept for the original date in May, the organizers of Deutsche Messe AG are now postponing the trade show fo ... more

analytica China 2020 concludes successfully

More than 1,000 new products point to future trends

24-Nov-2020 analytica China 2020 came to a successful conclusion on November 18, 2020 at the Shanghai New International Expo Centre. The show brought together 1,009 exhibitors (2018: 950) and 112 represented companies and partners. 23,652 professional visitors attended. With six exhibition halls, eight ... more

All news on laborausstattung / laborbedarf

TTP Group opens Pharmaplan branch near Lonza AG in Visp, CH

11-Jun-2021 In response to the investment boom in the pharmaceutical industry, TTP Group is opening another Pharmaplan branch in Switzerland in the third quarter of 2021. With the new subsidiary at the biotech site in Visp, Pharmaplan is meeting the growing global demand for pharmaceutical engineering ... more

Evonik to market and develop new drug delivery platform for mRNA and gene therapy

Evonik and Stanford University sign research collaboration

11-Jun-2021 Evonik is working with Stanford University on a technology to deliver mRNA to tissues and organs that goes beyond the capabilities of lipid nanoparticles (LNPs). This polymer-based platform complements Evonik’s existing portfolio of lipid-based drug delivery, including LNPs. Starting this m ... more

Targeted drug delivery without the normal side effects

Indo-Irish Biotech Startup Secures Funding to Accelerate Cancer and Rare Genetic Disease Therapy

09-Jun-2021 CyGenica has announced that it has raised USD $1.4 million in a seed fund investment round, led by global venture capital investor SOSV. The funding round will accelerate validation of CyGenica’s proprietary technology which enables safe, targeted and affordable intercellular drug delivery. ... more

Lonza and Moderna Announce Further Collaboration For Drug Substance Manufacturing of COVID-19 Vaccine Moderna in the Netherlands

03-Jun-2021 Lonza announced the expansion of its collaboration with Moderna. The expanded collaboration will further extend the manufacture of the drug substance for the COVID-19 Vaccine Moderna and provides for the installation of a new manufacturing line for drug substance production at Lonza’s Gelee ... more

CureVac’s First-Generation COVID-19 Vaccine Candidate, CVnCoV, Continues Toward Phase 2b/3 Efficacy Readout in Variant-rich Environment Following DSMB Recommendation

01-Jun-2021 CureVac N.V. announced that the independent Data Safety Monitoring Board (DSMB) has confirmed that the pivotal Phase 2b/3 study (HERALD) for CureVac’s first-generation COVID-19 vaccine candidate, CVnCoV, has passed a first interim analysis at 59 adjudicated COVID-19 cases. The DSMB confirme ... more

Numab Therapeutics Completes Oversubscribed CHF 100 Million Series C Financing

Proceeds will be Used to Accelerate Advancement of Pipeline of Multispecific Antibodies in Oncology

26-May-2021 Numab Therapeutics AG, a clinical stage biopharmaceutical company developing next-generation multispecific antibody-based immunotherapies for cancer and inflammation, announced the closing of a CHF 100 million (approximately USD 110 million) Series C financing. The financing was co-led by n ... more

Former Merck CEO appointed Chair of the AiCuris Supervisory Board

26-May-2021 AiCuris Anti-infective Cures AG announced that the Supervisory Board appointed Dr. Stefan Oschmann as chairman. He succeeds Helmut Jeggle, Chief Executive Officer of Salvia GmbH, who stepped down as planned from his role as Interim-Chairman of the initial Supervisory Board of AiCuris AG. He ... more

Optogenetic methods restore partial vision in a blind patient

Milestone towards a gene therapy that could restore vision

26-May-2021 An international research team has shown that optogenetic therapy has helped to partially regain visual function in a patient with retinitis pigmentosa. This is a milestone towards a gene therapy that could restore vision. Clinical trial results show for the first time that optogenetic meth ... more

BD to Build New €165 Million Manufacturing Facility in Zaragoza, Spain

Support Ongoing Strong Growth of Pre-Filled Drug Delivery Business

20-May-2021 BD (Becton, Dickinson and Company) will build a €165 million ($200 million USD) high-tech manufacturing facility in the city of Zaragoza, located in the Aragon region of Spain, that will create up to 600 jobs by 2030. BD plans to begin construction of the new plant in late 2021, and the new ... more

Scientists prefer to found companies as part-time entrepreneurs

Start-ups by researchers are significantly more stable than start-ups in general

20-May-2021 Infrastructure at the university promoting start-ups and contacts in the business community has a positive effect on the start-up success of scientists. This is the result of a study by the IfM Bonn, which examined the start-up behaviour of academics at German universities over a period of ... more

All news on pharma

What happens in brain cells affected by Alzheimer’s disease?

Studies on tissue from patients and mini-brains made from stem cells shed light on the disease

15-Jun-2021 In addition to plaques that accumulate outside of nerve cells in the brain, Alzheimer’s disease is also characterised by changes inside these cells. Researchers from the Cell Signalling research group at the Chair of Molecular Biochemistry at RUB, headed by Dr. Thorsten Müller, have been st ... more

Researchers turned transparent calcite into artificial gold

Breakthrough in metamaterials: New material can serve as a platform for innovative cancer treatments

15-Jun-2021 For the first time in the world, researchers at Tel Aviv University developed an innovative nanotechnology that transforms a transparent calcite nanoparticle into a sparkling gold-like particle. In other words, they turned the transparent particle into a particle that is visible despite its ... more

COVID-19 can cause severe inflammation in the brain

Various immune cells in the brainstem cause formation of inflammatory nodules

15-Jun-2021 Both during and after infection with the Coronavirus SARS-CoV-2, patients may suffer from severe neurological symptoms, including “anosmia”, the loss of taste and smell typically associated with COVID-19. Along with direct damage caused by the virus, researchers suspect a role for excessive ... more

Understanding the evolution of viruses

Key step in the evolutionary history of viruses in a laboratory experiment recreated

14-Jun-2021 Viruses have always had a major influence on life. They emerged a few billion years ago, precisely when is difficult to estimate. There are also several theories as to how viruses originated. While exploring one possibility, researchers at ETH Zurich have managed to recapitulate a potential ... more

Why heart patients should avoid cream cake

Study examines the influence of rumensic acid on heart muscle fibers

14-Jun-2021 Cardiovascular diseases are the most common cause of death in Germany. Important triggers for this are stress, lack of exercise and an unhealthy diet. Now a research team led by Professor Dr. Dietmar Manstein, Director of the Institute of Biophysical Chemistry at Hannover Medical School (MH ... more

A Trojan horse against tuberculosis

New transport route for antibiotics directly into infected cells

14-Jun-2021 Tuberculosis is still the infectious disease that is responsible for the highest number of deaths worldwide. It is caused by Mycobacterium tuberculosis, a bacterium that infects cells in the lungs. There, the pathogen is hardly accessible to most antibiotics. In addition, resistance to exis ... more

One for all: Convergent mechanism of ageing discovered

This may provide a new possibility to broadly improve human health during ageing

11-Jun-2021 Several different causes of ageing have been discovered, but the question remains whether there are common underlying mechanisms that determine ageing and lifespan. Researchers from the Max Planck Institute for Biology of Ageing and the CECAD Cluster of Excellence in Ageing research at the ... more

Bacteria hijack latent phage of competitor

From a quiet companion into a deadly parasite: Biochemists discover highly selective phage activation based on signal molecule

11-Jun-2021 Bacteriophages are still a relatively unknown component of the human microbiome. However, they can play a powerful role in the life cycles of bacteria. Biochemist Thomas Böttcher from the University of Vienna and PhD student Magdalena Jancheva were able to show for the first time how Pseudo ... more

A well-known anti-ageing compound with a new target

Researchers discover an unexpected link between DNA winding and metabolism in the gut to ameliorate ageing

10-Jun-2021 Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell. An international team of researchers at the Max Planck Institute for Biology of Ageing, the CECAD Cluster of Excellence in Ageing research at t ... more

Controlling insulin production with a smartwatch

Green light from the smartwatch activates the gene

09-Jun-2021 ETH Zurich researchers have developed a gene switch that can be operated with the green LED light emitted by commercial smartwatches. This revolutionary approach could be used to treat diabetes in the future. Many modern fitness trackers and smartwatches feature integrated LEDs. The green l ... more

All news on healthcare
News by department
  • Products

    CureVac’s First-Generation COVID-19 Vaccine Candidate, CVnCoV, Continues Toward Phase 2b/3 Efficacy Readout in Variant-rich Environment Following DSMB Recommendation

    01-Jun-2021 CureVac N.V. announced that the independent Data Safety Monitoring Board (DSMB) has confirmed that the pivotal Phase 2b/3 study (HERALD) for CureVac’s first-generation COVID-19 vaccine candidate, CVnCoV, has passed a first interim analysis at 59 adjudicated COVID-19 cases. The DSMB confirme ... more

    Second-Generation COVID-19 Vaccine Candidate Demonstrates High Immunogenicity Against Virus Variants in Preclinical Study

    Fast onset of strong neutralizing antibody titers after first vaccination

    14-May-2021 CureVac N.V. announced together with its collaboration partner GSK, first preclinical data in a rat model, showing that its second-generation COVID-19 vaccine candidate, CV2CoV, induces high levels of antigen production as well as strong and dose-dependent immune responses in vaccinated ani ... more

    Atriva Therapeutics to Speed up Development of COVID-19 Drug with Federal Funding

    Product candidate ATR-002 could help hospital patients with COVID-19 avoid ventilation and intensive care treatment

    27-Apr-2021 Atriva Therapeutics GmbH has secured up to €11.4 million in federal funding. The company, founded in 2015, announced today that it was selected for research funding from the German Federal Ministry of Education and Research (BMBF). Atriva will use the funds to advance its drug ATR-002 towar ... more

  • Business

    Hope in the fight against cancer: They build proteins that are not known to nature

    Basel-​based biotech startup has big ideas for the future: it aims to take protein engineering into a new era

    15-Jun-2021 Using chemical synthesis, Bright Peak Therapeutics can produce proteins that have never before existed. This holds great potential for cancer immunotherapy. The Basel-​based spin-​off has its beginnings at ETH Zurich. Jeffrey Bode’s long, bold journey began over an after-​work beer in Tokyo ... more

    TTP Group opens Pharmaplan branch near Lonza AG in Visp, CH

    11-Jun-2021 In response to the investment boom in the pharmaceutical industry, TTP Group is opening another Pharmaplan branch in Switzerland in the third quarter of 2021. With the new subsidiary at the biotech site in Visp, Pharmaplan is meeting the growing global demand for pharmaceutical engineering ... more

    Siegfried affected by attack on its IT systems

    Production interruption with the exception of the two sites in Spain

    25-May-2021 The Siegfried Group's IT network has become the target of a malware attack. The company immediately initiated extensive measures to ensure the safety of its employees and facilities at all times and to avert further damage. The root cause has been identified and the recovery of the systems ... more

  • Price Development

    Are the high prices of cancer drugs justified?

    Does the cost correspond to the particular drug’s effectiveness in combating the disease?

    05-May-2020 Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international UZH study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clin ... more

    Drug costs vary by more than 600% in study of 10 high-income countries

    13-Jun-2017 In a study of 10 high-income countries with universal health care, costs for prescription drugs in 6 of the largest categories of primary care medicines varied by more than 600%. All countries except Canada offered universal coverage of outpatient prescription drugs. The study looked at dat ... more

    Cell Medica granted Orphan Drug designation for novel cellular therapy

    18-Mar-2015 Cell Medica announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to the company’s cancer immunotherapy treatment, referred to as CMD-003, under development for Epstein-Barr Virus (EBV) positive non-Hodgkin lymphomas. Additionally, the company announ ... more

  • Research

    What happens in brain cells affected by Alzheimer’s disease?

    Studies on tissue from patients and mini-brains made from stem cells shed light on the disease

    15-Jun-2021 In addition to plaques that accumulate outside of nerve cells in the brain, Alzheimer’s disease is also characterised by changes inside these cells. Researchers from the Cell Signalling research group at the Chair of Molecular Biochemistry at RUB, headed by Dr. Thorsten Müller, have been st ... more

    Hope in the fight against cancer: They build proteins that are not known to nature

    Basel-​based biotech startup has big ideas for the future: it aims to take protein engineering into a new era

    15-Jun-2021 Using chemical synthesis, Bright Peak Therapeutics can produce proteins that have never before existed. This holds great potential for cancer immunotherapy. The Basel-​based spin-​off has its beginnings at ETH Zurich. Jeffrey Bode’s long, bold journey began over an after-​work beer in Tokyo ... more

    Researchers turned transparent calcite into artificial gold

    Breakthrough in metamaterials: New material can serve as a platform for innovative cancer treatments

    15-Jun-2021 For the first time in the world, researchers at Tel Aviv University developed an innovative nanotechnology that transforms a transparent calcite nanoparticle into a sparkling gold-like particle. In other words, they turned the transparent particle into a particle that is visible despite its ... more

  • People

    Former Merck CEO appointed Chair of the AiCuris Supervisory Board

    26-May-2021 AiCuris Anti-infective Cures AG announced that the Supervisory Board appointed Dr. Stefan Oschmann as chairman. He succeeds Helmut Jeggle, Chief Executive Officer of Salvia GmbH, who stepped down as planned from his role as Interim-Chairman of the initial Supervisory Board of AiCuris AG. He ... more

    Merck Announces Changes in Operating Model for Healthcare Business Sector

    Chris Round will leading the US and Canada Healthcare business

    19-May-2021 Merck announced changes in its operating model for the Healthcare business sector. Chris Round will become President of EMD Serono leading the North America Healthcare business; Andrew Paterson will assume the position of Chief Marketing Officer; and recruitment is ongoing for the position ... more

    CatalYm Appoints Industry Leader Dr. Phil L’Huillier as Chief Executive Office

    06-May-2021 CatalYm GmbH, a biopharmaceutical company developing novel cancer immunotherapies, announced the appointment of Dr. Phil L’Huillier as Chief Executive Officer (CEO), effective May 17, 2021. Dr. Phil L’Huillier brings over two decades of experience in executive leadership positions in the ph ... more

  • Finances

    Remote-controlled labs - Lab of the future is liberating scientists from the limitations of their location

    California-based startup Strateos closes $56 Million Series B financing

    10-Jun-2021 Strateos, Inc., a pioneer in the development of remote access laboratories and lab control software for life science research, announced the closing of its $56.1 million Series B financing led by DCVC and Lux Capital with participation from new investors including Eli Lilly and Company, All ... more

    Targeted drug delivery without the normal side effects

    Indo-Irish Biotech Startup Secures Funding to Accelerate Cancer and Rare Genetic Disease Therapy

    09-Jun-2021 CyGenica has announced that it has raised USD $1.4 million in a seed fund investment round, led by global venture capital investor SOSV. The funding round will accelerate validation of CyGenica’s proprietary technology which enables safe, targeted and affordable intercellular drug delivery. ... more

    Origin.Bio secures $15 million funding to help manufacturers create a more sustainable future

    Start-up connects bioengineers with nature to hack entirely new organisms, freeing manufacturers from petrochemical dependency

    02-Jun-2021 Origin.Bio-- a synthetic biology company that replicates and improves ingredients from traditional chemical industrialisation processes, freeing manufacturers from petrochemical dependency -- today announces a $15m funding round led by EQT Ventures. Existing investor BlueYard Capital also p ... more

  • Cooperation

    Evonik to market and develop new drug delivery platform for mRNA and gene therapy

    Evonik and Stanford University sign research collaboration

    11-Jun-2021 Evonik is working with Stanford University on a technology to deliver mRNA to tissues and organs that goes beyond the capabilities of lipid nanoparticles (LNPs). This polymer-based platform complements Evonik’s existing portfolio of lipid-based drug delivery, including LNPs. Starting this m ... more

    Lonza and Moderna Announce Further Collaboration For Drug Substance Manufacturing of COVID-19 Vaccine Moderna in the Netherlands

    03-Jun-2021 Lonza announced the expansion of its collaboration with Moderna. The expanded collaboration will further extend the manufacture of the drug substance for the COVID-19 Vaccine Moderna and provides for the installation of a new manufacturing line for drug substance production at Lonza’s Gelee ... more

    White biotechnology enables carbon recycling

    LanzaTech and BASF achieve first milestone in utilizing industrial off-gases for chemical production

    14-May-2021 Transforming the carbon contained in industrial off-gases into valuable chemicals is the aim of a partnership between LanzaTech and BASF. Now the partners have achieved a key first success: With the help of special bacteria, they have been able to produce n-octanol at laboratory scale from ... more

  • Technology

    Evonik makes follow-on investment into In Ovo to support launch of gender-testing machine for eggs

    Biotechnology start-up reaches commercialization stage for its technology

    06-Apr-2021 Evonik has made a follow-up investment in the biotechnology start-up In Ovo through its venture capital unit. The investment comes as the young company reaches the commercialization stage for its technology and is bringing its gender-testing machine for eggs to the market. Together with co- ... more

    High-tech start-ups benefit from Twitter hype

    Study shows correlation between Twitter sentiment and the valuation of start-ups by venture capitalists

    18-Feb-2021 The short message service Twitter has played a prominent role in US politics in recent weeks and months and attracted a lot of attention. Even in business, Twitter users' tweets are being closely followed and used as a basis for decision-making. A new study shows that venture capitalists ca ... more

    LGC acquires The Native Antigen Company

    Strengthening LGC'S offer to the IVD sector

    10-Jul-2020 LGC announced the acquisition of The Native Antigen Company (NAC), supplier of high quality infectious disease antigens and antibodies. NAC is a developer, manufacturer and supplier of critical reagents to the in vitro diagnostic (IVD), pharmaceutical and academic sectors. It offers a compr ... more

  • Laws

    Japan and Singapore Grant CRISPR Patents to Merck

    27-Nov-2019 Merck announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide. “Paired nickases represent a significant step in incre ... more

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    Merck Awarded Canadian CRISPR Nickase Patent for Foundational Genome-Editing Technology

    05-Mar-2019 Merck announced that the Canadian Patent Office has allowed Merck’s patent application directed to the use of paired CRISPR nickases in eukaryotic cells. The patent provides an important and more specific solution for scientists who need accurate methods when developing treatments for diffi ... more

  • Market

    M&A in chemicals and life sciences slowed down by global lockdowns

    Race for COVID-19 vaccine

    13-Jul-2020 In the first half of this year, the transaction volume of mergers and acquisitions in the chemical and life sciences industries has decreased dramatically. The volume of deals announced in the first six months is only $84 billion. Compared to the previous year (389 billion dollars), this is ... more

    Many of the deadliest cancers receive the least amount of research funding

    'Embarrassing' or stigmatized cancers like lung and liver are underfunded

    23-Jul-2019 Many of the deadliest or most common cancers get the least amount of nonprofit research funding, according to a new Northwestern Medicine study that examined the distribution of nonprofit research funding in 2015 across cancer types. Colon, endometrial, liver and bile duct, cervical, ovaria ... more

    Gene Editing Tools Gain an Uptick in Sales With Emphasis on Rare Genetic Disorder Management

    22-Jul-2019 According to latest research by FMI, the global gene editing tools market is estimated to have accounted for more than US$ 258 Mn in terms of value in 2018. The report on the gene editing tools market further projects that the gene editing tools market is likely to grow at a CAGR of over 18 ... more

  • Politics

    What the Biden-Harris administration means for chemistry

    The new administration has inherited a global pandemic and worsening climate change, among other science-related issues

    10-Feb-2021 The inauguration of Joe Biden and Kamala Harris marks a new era for science policy in the U.S. and beyond. The new administration has inherited a global pandemic and worsening climate change, among other science-related issues. A cover story in Chemical & Engineering News (C&EN), the weekly ... more

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    ECETOC Task Force provides new insights

    Toxicity testing of microparticles and poorly soluble liquids in the water environment

    15-Jan-2019 A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ... more

  • Manufacturing

    Siegfried restarts production after cyber attack

    31-May-2021 The Siegfried Group has largely overcome the consequences of the cyber attack that occurred shortly before Pentecost and has begun to ramp up production again. Some sites had continued or resumed operations to a certain extent last week. Other sites will follow in the next days, including t ... more

    Siegfried affected by attack on its IT systems

    Production interruption with the exception of the two sites in Spain

    25-May-2021 The Siegfried Group's IT network has become the target of a malware attack. The company immediately initiated extensive measures to ensure the safety of its employees and facilities at all times and to avert further damage. The root cause has been identified and the recovery of the systems ... more

    BD to Build New €165 Million Manufacturing Facility in Zaragoza, Spain

    Support Ongoing Strong Growth of Pre-Filled Drug Delivery Business

    20-May-2021 BD (Becton, Dickinson and Company) will build a €165 million ($200 million USD) high-tech manufacturing facility in the city of Zaragoza, located in the Aragon region of Spain, that will create up to 600 jobs by 2030. BD plans to begin construction of the new plant in late 2021, and the new ... more

  • Career

    Eppendorf with worldwide setting program

    Around 250 vacancies at all locations by the end of 2019

    26-Apr-2019 The Eppendorf Group is creating around 250 new jobs worldwide this year. A large proportion of the new jobs will be created in Hamburg at the headquarters of the globally active life sciences company and is an important component of Eppendorf's growth strategy. "Eppendorf is growing strongl ... more

    Lower pension, shorter life

    12-Apr-2019 Income and social status have an increasing effect on life expectancy in Germany. On average, men with very low retirement pay die five years earlier than those who are much better off. Poverty shortens life. According to a study by researchers at the Max Planck Institute for Demographic Re ... more

    KNAUER among the top one percent of employers in Germany

    28-Feb-2019 In the study "Leading Employers Germany 2019", the Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER was ranked as one of the best employers for the second time. This makes KNAUER one of the companies with the best ratings in an independent meta-study conducted ... more

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