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Why and how we age

A low level of the stress hormone cortisol contributes to the ageing process

03-Jul-2020 Why do we age? What exactly is happening in our bodies? And can we do anything about it? Mankind has sought answers to these questions since time immemorial. While the pharmaceutical scientists Alexandra K. Kiemer and Jessica Hoppstädter from Saarland University are not claiming to have sol ... more

Well shielded but highly active

Architecture is key: Biomolecule metal–organic hybrids with high bioactivity

03-Jul-2020 Biomacromolecules incorporated into tailored metal–organic frameworks using peptide modulators are well shielded but highly active thanks to carefully tuned nanoarchitecture. As scientists report in the journal Angewandte Chemie, this strategy can be used to synthesize an “artificial cell” ... more

Algae as living biocatalysts for a green industry

Discovery could lead to more environmental protection in the chemical industry

03-Jul-2020 Many substances that we use every day only work in the right 3D structure. Natural enzymes could produce these in an environmentally friendly way – if they didn’t need a co-substrate that is expensive to produce to date. A research team at Ruhr-Universität Bochum (RUB) has discovered exactl ... more

New method reveals how the Parkinson's disease protein damages cell membranes

The method makes it possible to study tiny quantities of biological molecules without using fluorescent markers

03-Jul-2020 In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a new method developed at Chalmers University of Technology, Sweden, rev ... more

Merck acquires a French company

Merck Advances Bioprocessing Capabilities with Raman Technology Sensor Acquisition

02-Jul-2020 Merck enhanced its advanced bioprocess portfolio through the acquisition of RESOLUTION Spectra Systems, a Meylan, France-based leader in bioprocess analytical monitoring. The company offers Raman spectroscopy analysis through its GMP-ready instrumentation and software. Financial details of ... more

Pfizer and BioNTech Announce Early Positive Data from an Ongoing Phase 1/2 Study of mRNA-based Vaccine Candidate Against SARS-CoV-2

Efforts to manufacture the leading candidates, at risk, are gearing up

02-Jul-2020 Pfizer Inc. and BioNTech SE announced preliminary U.S. data from the most advanced of four investigational vaccine candidates from their BNT162 mRNA-based vaccine program, Project Lightspeed, against SARS-CoV-2, the virus causing the current global pandemic. The BNT162 program is evaluating ... more

Dust mite allergens trigger inflammatory responses

Dust mite allergens activate the pulmonary immune system, thereby triggering allergies

02-Jul-2020 A research team at MedUni Vienna, working in cooperation with the Johns Hopkins University in Baltimore, has discovered how certain dust mite allergens activate a well-known inflammatory factor – serum amyloid A protein –and can thus “trim” the lung tissue “in the direction of allergy”. The ... more

Spider silk can create lenses useful for biological imaging

Lenses built on dragline spider silk generate a special type of light jet that can image large biological areas with high resolution

02-Jul-2020 Spiders -- what are they good for? The answer, it turns out, is more than just insect control. Spider silk is useful for a variety of biomedical applications. It exhibits mechanical properties superior to synthetic fibers for tissue engineering, and it is not toxic or harmful to living cell ... more

Researchers identify multiple molecules that shut down SARS-Cov-2 polymerase reaction

A library of molecules with unique structural and chemical features inhibit the novel coronavirus polymerase, a key drug target for COVID-19

02-Jul-2020 SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells. Terminating the polymerase reaction will stop the growth of the coronavirus, leading to its eradication by the human host's immune system. ... more

A novel strategy to generate useful chiral compounds

Newly designed ligands for a catalytic reaction to synthesize drugs and useful compounds

01-Jul-2020 Currently, various therapeutic compounds in the market, such as proteins, enzymes, and amino acids, are "chiral compounds"--molecules with two structures that are "mirror" images of each other but cannot be superimposed. Although the two variants of the molecule, also called "enantiomers," ... more

All news

analytica 2020: Great exhibitor resonance for the autumnal fair

Trade fair to implement the government’s protection and hygiene concept

30-Jun-2020 After the postponement to the fall, there are now increasing signs for a success of analytica in October. The number of exhibitors has currently almost reached the level of the previous event. Most recently, the Bavarian State Government has cleared the way for analytica: From September 01 ... more

RNA structures by the thousands

New method to determine the structures of all RNA molecules in a bacterial cell at once: In the past, it would have taken many research careers

19-Jun-2020 Every cell contains thousands of different RNA molecules. In the past, it would have taken many research careers to decipher their structures using traditional methods. But not anymore. Researchers from Bochum and Münster have developed a new method to determine the structures of all RNA mo ... more

The relationship of proteins

Researchers have for the first time uncovered the proteome of 100 organisms from all domains of life

19-Jun-2020 Proteins control life as one of the most important biomolecules - as enzymes, receptors, signal or structural building blocks. Researchers at the Max Planck Institute (MPI) of Biochemistry have for the first time uncovered the proteomes of 100 different organisms. The selected specimens com ... more

Could the blood of COVID-19 patients be used to predict disease progression?

Study discovers differences in the blood samples of severe and mild cases

09-Jun-2020 Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have identified 27 proteins which are present at different levels in the blood of COVID-19 patients, depending on the severity of their symptoms. These biomarker profiles could be used to predict disease p ... more

Roche acquires Stratos Genomics

Further develop DNA based sequencing for diagnostic use

25-May-2020 Roche announced that it has acquired Stratos Genomics, an early-stage sequencing technology company to advance the development of Roche’s nanopore sequencer. The acquisition provides Roche access to Stratos Genomics unique chemistry, Sequencing by Expansion (SBX™). The Roche nanopore sequen ... more

Single-cell RNA seq method developed to accurately quantify cell-specific drug effects in pancreatic islets

Findings could open up potential therapeutic avenues to treat Type 1 diabetes

14-May-2020 Researchers from Stefan Kubicek’s and Christoph Bock’s groups, at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, have developed a method to accurately assess the effect of specific drugs in isolated pancreatic tissue by using a refined single- ... more

Using mini colons to detect functional differences and weaknesses of colorectal cancer

Pooled in vitro and in vivo CRISPR-Cas9 screening identifies tumor suppressors in human colon organoids

07-May-2020 One of the main features of colorectal cancer is that there are considerable differences between the tumors of individual patients - at genetic level and hence in terms of the response to treatment too. Researchers from the German Cancer Consortium (DKTK) have developed a method that allows ... more

Real-time observation of enzymatic processes on DNA

Insights into the molecular processes involved in the detection of DNA strand breaks

05-May-2020 DNA strand breaks can contribute to the development of cancer and the ageing process. Researchers from the Departments of Biology and Chemistry of the University of Konstanz have now been able to observe in real time the molecular processes that take place at DNA strand breaks by means of i ... more

Herpes virus decoded using new methods

A comprehensive systems biological analysis of the herpes virus genome has caused some surprises

30-Apr-2020 The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening. Until now, scientists had assumed that there are about 80 so-called open reading frames (ORFs) in t ... more

Researchers build micro-device to detect bacteria, viruses

New process improves lab-on-chip devices to isolate drug-resistant strains of bacterial infection, viruses

22-Apr-2020 Engineering researchers developed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases. Using this new technology improves how clinicians isolate drug-resistant strains of bacterial infections and difficult-to-detect ... more

All news on bioanalytics

Well shielded but highly active

Architecture is key: Biomolecule metal–organic hybrids with high bioactivity

03-Jul-2020 Biomacromolecules incorporated into tailored metal–organic frameworks using peptide modulators are well shielded but highly active thanks to carefully tuned nanoarchitecture. As scientists report in the journal Angewandte Chemie, this strategy can be used to synthesize an “artificial cell” ... more

Algae as living biocatalysts for a green industry

Discovery could lead to more environmental protection in the chemical industry

03-Jul-2020 Many substances that we use every day only work in the right 3D structure. Natural enzymes could produce these in an environmentally friendly way – if they didn’t need a co-substrate that is expensive to produce to date. A research team at Ruhr-Universität Bochum (RUB) has discovered exactl ... more

Merck acquires a French company

Merck Advances Bioprocessing Capabilities with Raman Technology Sensor Acquisition

02-Jul-2020 Merck enhanced its advanced bioprocess portfolio through the acquisition of RESOLUTION Spectra Systems, a Meylan, France-based leader in bioprocess analytical monitoring. The company offers Raman spectroscopy analysis through its GMP-ready instrumentation and software. Financial details of ... more

Pfizer and BioNTech Announce Early Positive Data from an Ongoing Phase 1/2 Study of mRNA-based Vaccine Candidate Against SARS-CoV-2

Efforts to manufacture the leading candidates, at risk, are gearing up

02-Jul-2020 Pfizer Inc. and BioNTech SE announced preliminary U.S. data from the most advanced of four investigational vaccine candidates from their BNT162 mRNA-based vaccine program, Project Lightspeed, against SARS-CoV-2, the virus causing the current global pandemic. The BNT162 program is evaluating ... more

Controlling plant processes with light

Optogenetic tool enables targeted and reversible gene expression control in plants in the presence of ambient light

01-Jul-2020 A research team of biologists within the CEPLAS Cluster of Excellence at Heinrich Heine University Düsseldorf (HHU) has succeeded, together with colleagues from the University of Freiburg, to develop an optogenetic tool for use in plant research. The tool can be used to control plant proces ... more

analytica 2020: Great exhibitor resonance for the autumnal fair

Trade fair to implement the government’s protection and hygiene concept

30-Jun-2020 After the postponement to the fall, there are now increasing signs for a success of analytica in October. The number of exhibitors has currently almost reached the level of the previous event. Most recently, the Bavarian State Government has cleared the way for analytica: From September 01 ... more

BioNTech to Raise USD 250 Million in Private Placement

The private placement includes an investment in ordinary shares and a investment in 4-year mandatory convertible notes

30-Jun-2020 BioNTech SE announced a private investment of USD 250 million (EUR 223 million) by Temasek and other accredited investors. The private placement includes an investment of approximately USD 139 million in ordinary shares and a USD 112 million investment in 4-year mandatory convertible notes. ... more

Bit Bio secures $41.5 million of funding from top life sciences investors

Bit Bio’s aim is to decode “cellular identity” in order to generate every cell type of the human body

25-Jun-2020 Bit Bio, a Cambridge-based synthetic biology company combining data science and biology to code cells for the wellbeing of humanity, announced the close of a $41.5 million Series A investment, bringing the company’s total funding to $50 million. In a strong statement of support for the comp ... more

KETBIO announced TOP THREE of EU BIOTECH

Green Aviation Fuels, Decentralised Waste Water Treatment, Industrial Maritime Enzymes

23-Jun-2020 During its high-level Booster Conference, 17 June 2020 with + 100 participants attending the online event, the KETBIO biotech transfer initiative has announced the top ranked EU Biotech projects. The winners, who were ranked by industry experts as the TOP TEN EU BIOTECH, have been selected ... more

A salt solution toward better bioelectronics

A water-stable dopant enhances and stabilizes the performance of electron-transporting organic electrochemical transistors

18-Jun-2020 Doping is commonly used to improve performance in semiconducting devices but has not previously been successful for electron transporting or n-type, organic electronic materials. Now, an approach developed by KAUST uses a dopant, an additive that boosts the electronic performance and water ... more

All news on biotechnology

analytica 2020: Great exhibitor resonance for the autumnal fair

Trade fair to implement the government’s protection and hygiene concept

30-Jun-2020 After the postponement to the fall, there are now increasing signs for a success of analytica in October. The number of exhibitors has currently almost reached the level of the previous event. Most recently, the Bavarian State Government has cleared the way for analytica: From September 01 ... more

Artificial intelligence classifies colorectal cancer using IR imaging

Infrared microscopy can automatically detect the type of intestinal tumour within only 30 minutes

26-Jun-2020 A research team from the Prodi Centre for Protein Diagnostics at Ruhr-Universität Bochum (RUB) has used infrared (IR) microscopes based on quantum cascade lasers to classify tissue samples of colorectal cancer from routine clinical operations in a marker-free and automated way. Artificial i ... more

Detecting antibodies with glowing proteins, thread and a smartphone

Approach could provide a small, inexpensive alternative to expensive, sophisticated instruments in labs

22-Jun-2020 To defend the body, the immune system makes proteins known as antibodies that latch onto the perceived threat, be it HIV, the new coronavirus or, as is the case in autoimmune disease, part of the body itself. In a new proof-of-concept study in ACS Sensors, researchers describe a new system ... more

Start-up Raises 16.3 million Euros to Prepare Market Launch of its SARS-CoV-2 Rapid Testing System

“Mini-laboratory” provides test results in 30 to 40 minutes

27-May-2020 Spindiag GmbH, a medical technology start-up company founded four years ago as a spin-off of the Hahn-Schickard Institute for Microanalytical Systems, announced the completion of a 16.3 million Euros (USD 17.8 million) Series B financing round as expected. Existing investors as well as Thin ... more

Researcher Develops One Minute Coronavirus Test

COVID-19 samples can be collected using a simple breath test or throat and nose swabs

15-May-2020 Ben-Gurion University of the Negev's Prof. Gabby Sarusi has developed and is now validating a test that identifies carriers of the COVID-19 virus in less than a minute with greater than 90% accuracy and at a dramatically lower price than any other method available. Clinical trials in conjun ... more

New x-ray method for Corona diagnosis ready for patient testing

Low-dose radiographs could reveal typical lung changes

12-May-2020 Researchers at the Technical University of Munich (TUM) have developed an innovative x-ray method for lung diagnostics, which they now plan to test in one of its first applications for diagnosis of the respiratory ailment Covid-19 caused by Coronavirus. The method could clearly identify abn ... more

Print your own laboratory-grade microscope for US$18

An open-source design gives schools, homes and labs the chance to 3D print their own precision microscopes

06-May-2020 For the first time, labs around the world can 3D print their own precision microscopes to analyse samples and detect diseases , thanks to an open-source design created at the University of Bath. The OpenFlexure Microscope, described in Biomedical Optics Express, is a fully automated, labora ... more

Precise diagnostics with artificial intelligence

BIH Digital Health Accelerator guides Aignostics GmbH through its spin-off

27-Apr-2020 The usual way to determine if a suspicious lump is cancerous involves microscopic examination in a pathology laboratory. To ease the workload of pathologists who face a rising number of cancer cases and increasingly finer molecular details and to enable tailored treatments, scientists at th ... more

Diagnostic biosensor quickly detects SARS-CoV-2 from nasopharyngeal swabs

New test analyzes patient samples without any sample preparation steps

24-Apr-2020 According to many experts, early diagnosis and management are critical for slowing the spread of SARS-CoV-2, the new coronavirus that causes COVID-19. Therefore, the race is on to develop diagnostic tests for the virus that are faster, easier and more accurate than existing ones. Now, resea ... more

A new biosensor for the COVID-19 virus

Detection in the environment

23-Apr-2020 A team of researchers from Empa, ETH Zurich and Zurich University Hospital has succeeded in developing a novel sensor for detecting the new coronavirus. In future it could be used to measure the concentration of the virus in the environment - for example in places where there are many peopl ... more

All news on diagnostics

analytica 2020: Great exhibitor resonance for the autumnal fair

Trade fair to implement the government’s protection and hygiene concept

30-Jun-2020 After the postponement to the fall, there are now increasing signs for a success of analytica in October. The number of exhibitors has currently almost reached the level of the previous event. Most recently, the Bavarian State Government has cleared the way for analytica: From September 01 ... more

Eppendorf acquires centrifuge business of Koki Holdings Co., Ltd.

20-Mar-2020 Eppendorf AG and Koki Holdings Co., Ltd., have reached an agreement that Eppendorf will acquire Koki’s centrifuge business, including the premium himac brand. A corresponding agreement was signed by both companies in Tokyo. The acquisition marks a targeted step by Hamburg-based Eppendorf AG ... more

analytica 2020 is postponed

New date in the fall of 2020

09-Mar-2020 Due to the increasing spread of the coronavirus (COVID-19) in Europe and on the basis of the recommendations of the Bavarian State Government as well as of the responsible health authorities, Messe München feels compelled to postpone analytica 2020. This measure is taken in consultation wit ... more

Wolfgang Kintzel to Become Cellbox Solutions’ CEO

26-Feb-2020 Cellbox Solutions announces the expansion of its Board of Directors and the appointment of a new CEO - Wolfgang Kintzel will start as Chief Executive Officer effective March 1, 2020. The founder Prof. Kathrin Adlkofer will support the board in the function as COO. Wolfgang Kintzel has an ex ... more

Simplifying Progress: Sartorius sharpens its brand focus

25-Feb-2020 New brand promise, new logo, new colors – Sartorius looks different now. The company has revised its brand look. At the focus of this relaunch is Sartorius’ new brand promise that it summarizes in its new claim: Simplifying Progress. With its products and technologies, the company aims to s ... more

Sartorius looks optimistically to 2020

19-Feb-2020 Sartorius confirmed its preliminary figures upon publication of its 2019 Annual Report. Group sales revenue rose in constant currencies by 14.8% (reported: +16.7%) to 1,827.0 million euros. Growth was almost entirely organic as the acquisition of the cell culture media specialist Biological ... more

The digital laboratory live and tangible

12-Feb-2020 Visitors to analytica 2020 can experience the laboratory of the future in a special show that is unique in the whole world: 18 partners from science and industry have joined forces to demonstrate device networking, collaborative robotics and user interaction, using the example of eight work ... more

Sartorius is set to grow further

Sartorius achieves significant increases in sales revenue and earnings again in 2019

29-Jan-2020 Sartorius has continued on its profitable growth track in fiscal 2019. The Group grew by double digits in sales revenue, order intake and earnings, recording gains in both divisions and across all regions. According to preliminary figures, Group sales revenue rose in constant currencies by ... more

Waters to Acquire Andrew Alliance

15-Jan-2020 Waters Corporation announced that it has entered into a definitive agreement to acquire Andrew Alliance, an innovator in specialty laboratory automation technology, including software and robotics. Andrew Alliance’s cloud-native software platform and modern interface dramatically improves t ... more

Eppendorf with new CEO dual leadership

Former CEO, Thomas Bachmann, left the company

10-Dec-2019 The Supervisory Board of Eppendorf AG has appointed Eva von Pelt, currently Chief Commercial Officer, and Dr. Peter Fruhstorfer, currently Head of Business Area Sample Handling, as Co-Chief Executive Officers of Eppendorf AG. Both will succeed Thomas Bachmann, the former President & CEO of ... more

All news on laborausstattung / laborbedarf

Pfizer and BioNTech Announce Early Positive Data from an Ongoing Phase 1/2 Study of mRNA-based Vaccine Candidate Against SARS-CoV-2

Efforts to manufacture the leading candidates, at risk, are gearing up

02-Jul-2020 Pfizer Inc. and BioNTech SE announced preliminary U.S. data from the most advanced of four investigational vaccine candidates from their BNT162 mRNA-based vaccine program, Project Lightspeed, against SARS-CoV-2, the virus causing the current global pandemic. The BNT162 program is evaluating ... more

A novel strategy to generate useful chiral compounds

Newly designed ligands for a catalytic reaction to synthesize drugs and useful compounds

01-Jul-2020 Currently, various therapeutic compounds in the market, such as proteins, enzymes, and amino acids, are "chiral compounds"--molecules with two structures that are "mirror" images of each other but cannot be superimposed. Although the two variants of the molecule, also called "enantiomers," ... more

BioNTech to Raise USD 250 Million in Private Placement

The private placement includes an investment in ordinary shares and a investment in 4-year mandatory convertible notes

30-Jun-2020 BioNTech SE announced a private investment of USD 250 million (EUR 223 million) by Temasek and other accredited investors. The private placement includes an investment of approximately USD 139 million in ordinary shares and a USD 112 million investment in 4-year mandatory convertible notes. ... more

Chemists find way to create "the building blocks of life"

Turning alcohol into key ingredients for new medicines

30-Jun-2020 Chemists have found a way to turn alcohol into amino acids, the building blocks of life. In a study published in the journal Nature Chemistry, researchers explained the transformation, which involves selectively identifying and replacing molecular bonds with unprecedented precision. The fin ... more

X-rays size up protein structure at the 'heart' of COVID-19 virus

The protease protein is both shaped like a heart and functions as one, allowing the virus to replicate and spread

30-Jun-2020 A team of researchers at the Department of Energy's Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease -- the enzyme that enables the virus to reproduce. The X-ray measurements mark an important first step ... more

Merck initiates clinical Covid-19 study

First clinical trial of TLR7 and 8 inhibitor as a potential treatment for severe symptoms of Covid-19 infection

26-Jun-2020 Merck announced the U.S. Food and Drug Administration (FDA) has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. Merck will initiate a Phase II randomized, controlled clinical study evaluating the safety and efficacy of ... more

CSIC researchers will use a type of 'coronavirus parasite' to combat it

A project studies specific forms of coronavirus parasites to interfere with the replication capacity of SARS-CoV-2 and promote its elimination

23-Jun-2020 A team of researchers from the Spanish National Research Council (CSIC) is leading a project to develop antiviral drugs to prevent the replication of the SARS-CoV-2 coronavirus, which caused the Covid-19 pandemic. The study focuses on the so-called DIPs (Defective Interfering Particles), a ... more

Better Than Cyclodextrins

Molecular Containers for the Sequestration of Neurotransmitter Drugs in Water

19-Jun-2020 Molecular containers that remove drugs, toxins, or malodorous substances from the environment are called sequestering agents. Scientists have developed a class of molecular containers that specifically sequester neurotransmitter antagonists. The barrel-shaped molecules called Pillar[n]MaxQ ... more

CureVac Receives Regulatory Approval to Initiate Phase 1 Clinical Trial of its SARS-CoV-2 Vaccine Candidate

Trial will start promptly and will be conducted in Germany and Belgium

18-Jun-2020 CureVac AG announced that the German Health Authority Paul-Ehrlich-Institute (PEI) and the Belgian Federal Agency for Medicines and Health Products (FAMHP) have approved the Phase 1 clinical trial for its vaccine program to prevent SARS-CoV-2 infection. The trial will be conducted in German ... more

Fujifilm to invest 928 million USD to expand its large scale biologics production facility in Denmark

Doubling the drug substance production capacity

15-Jun-2020 FUJIFILM Corporation will make a major capital investment of approximately 100 billion yen (928 million USD) in the Denmark site of FUJIFILM Diosynth Biotechnologies, a leading contract development and manufacturing organization (CDMO) for biologics and advanced therapies. The capital inves ... more

All news on pharma

Why and how we age

A low level of the stress hormone cortisol contributes to the ageing process

03-Jul-2020 Why do we age? What exactly is happening in our bodies? And can we do anything about it? Mankind has sought answers to these questions since time immemorial. While the pharmaceutical scientists Alexandra K. Kiemer and Jessica Hoppstädter from Saarland University are not claiming to have sol ... more

New method reveals how the Parkinson's disease protein damages cell membranes

The method makes it possible to study tiny quantities of biological molecules without using fluorescent markers

03-Jul-2020 In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a new method developed at Chalmers University of Technology, Sweden, rev ... more

Dust mite allergens trigger inflammatory responses

Dust mite allergens activate the pulmonary immune system, thereby triggering allergies

02-Jul-2020 A research team at MedUni Vienna, working in cooperation with the Johns Hopkins University in Baltimore, has discovered how certain dust mite allergens activate a well-known inflammatory factor – serum amyloid A protein –and can thus “trim” the lung tissue “in the direction of allergy”. The ... more

Researchers identify multiple molecules that shut down SARS-Cov-2 polymerase reaction

A library of molecules with unique structural and chemical features inhibit the novel coronavirus polymerase, a key drug target for COVID-19

02-Jul-2020 SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells. Terminating the polymerase reaction will stop the growth of the coronavirus, leading to its eradication by the human host's immune system. ... more

Cow's milk protein beta-lactoglobulin prevents allergies

New key molecule for the so-called protective farm effect

01-Jul-2020 Numerous studies have shown that growing up on a farm and drinking natural, unprocessed cow's milk in early childhood protects against the development of immunoglobulins E (IgE), which are responsible for allergy symptoms. A recent study led by Franziska Roth-Walter and Erika Jensen-Jarolim ... more

New approach drives bacteria to produce potential antibiotic, antiparasitic compounds

Researchers used a variety of techniques, including genome mining, to identify bacteria that produce defensive compounds in response to hormone exposure

30-Jun-2020 Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches. The researchers wanted ... more

Circular RNA makes fruit flies live longer

One step closer to the mysterious circRNAs

29-Jun-2020 Ribonucleic acid, or RNA, is part of our genetic code and present in every cell of our body. The best known form of RNA is a single linear strand, of which the function is well known and characterized. But there is also another type of RNA, so-called “circular RNA”, or circRNA, which forms ... more

Children of academics exhibit more stress

If the stress hormone level is elevated for a long time, this can be seen in the hair

29-Jun-2020 Starting university is an exciting phase for everyone. However, children from academic households exhibit significantly more stress during this period than those from non-academic families. A Swiss-German research team has found this out by analysing the hair of female first-year students. ... more

Receptor makes mice strong and slim

The corresponding signaling pathways might also exist in humans

29-Jun-2020 Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects. Experiments with human cell cultures suggest that the corresponding signaling pathways might also exis ... more

Bioactive natural compounds for the fight against cancer

New synthesis route manages without toxic and expensive oxidizing agent and at the same time proves to be much more efficient

29-Jun-2020 Phytoalexins are bioactive phytochemicals that have attracted much attention in recent years due to their health-promoting effects in humans and their vital role in plant health. Chemists at TU Dresden have now developed a new and very efficient synthesis for these substances. With the new ... more

All news on healthcare
News by department
  • Products

    Pfizer and BioNTech Announce Early Positive Data from an Ongoing Phase 1/2 Study of mRNA-based Vaccine Candidate Against SARS-CoV-2

    Efforts to manufacture the leading candidates, at risk, are gearing up

    02-Jul-2020 Pfizer Inc. and BioNTech SE announced preliminary U.S. data from the most advanced of four investigational vaccine candidates from their BNT162 mRNA-based vaccine program, Project Lightspeed, against SARS-CoV-2, the virus causing the current global pandemic. The BNT162 program is evaluating ... more

    Merck initiates clinical Covid-19 study

    First clinical trial of TLR7 and 8 inhibitor as a potential treatment for severe symptoms of Covid-19 infection

    26-Jun-2020 Merck announced the U.S. Food and Drug Administration (FDA) has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia. Merck will initiate a Phase II randomized, controlled clinical study evaluating the safety and efficacy of ... more

    CureVac Receives Regulatory Approval to Initiate Phase 1 Clinical Trial of its SARS-CoV-2 Vaccine Candidate

    Trial will start promptly and will be conducted in Germany and Belgium

    18-Jun-2020 CureVac AG announced that the German Health Authority Paul-Ehrlich-Institute (PEI) and the Belgian Federal Agency for Medicines and Health Products (FAMHP) have approved the Phase 1 clinical trial for its vaccine program to prevent SARS-CoV-2 infection. The trial will be conducted in German ... more

  • Business

    Merck acquires a French company

    Merck Advances Bioprocessing Capabilities with Raman Technology Sensor Acquisition

    02-Jul-2020 Merck enhanced its advanced bioprocess portfolio through the acquisition of RESOLUTION Spectra Systems, a Meylan, France-based leader in bioprocess analytical monitoring. The company offers Raman spectroscopy analysis through its GMP-ready instrumentation and software. Financial details of ... more

    analytica 2020: Great exhibitor resonance for the autumnal fair

    Trade fair to implement the government’s protection and hygiene concept

    30-Jun-2020 After the postponement to the fall, there are now increasing signs for a success of analytica in October. The number of exhibitors has currently almost reached the level of the previous event. Most recently, the Bavarian State Government has cleared the way for analytica: From September 01 ... more

    Novel virtual trade fair for the process industry

    A new way to network and stay informed defies postponed or cancelled trade fairs: The "virtual process show" from 8 to 11 September 2020

    22-Jun-2020 From 8 to 11 September 2020, LUMITOS, a leading provider of B2B specialist portals and online marketing solutions, will be hosting the "virtual process show", a new digital meeting place for the process industry. In the halls of the virtual process show, an expected more than 100 exhibitors ... more

  • Price Development

    Are the high prices of cancer drugs justified?

    Does the cost correspond to the particular drug’s effectiveness in combating the disease?

    05-May-2020 Do high prices of some cancer medicines have a higher benefit than those drugs with lower prices? An international UZH study has concluded that, in general, there is no correlation between costs of a cancer drugs and their clinical benefit. The researchers are therefore calling for the clin ... more

    Drug costs vary by more than 600% in study of 10 high-income countries

    13-Jun-2017 In a study of 10 high-income countries with universal health care, costs for prescription drugs in 6 of the largest categories of primary care medicines varied by more than 600%. All countries except Canada offered universal coverage of outpatient prescription drugs. The study looked at dat ... more

    Cell Medica granted Orphan Drug designation for novel cellular therapy

    18-Mar-2015 Cell Medica announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to the company’s cancer immunotherapy treatment, referred to as CMD-003, under development for Epstein-Barr Virus (EBV) positive non-Hodgkin lymphomas. Additionally, the company announ ... more

  • Research

    Why and how we age

    A low level of the stress hormone cortisol contributes to the ageing process

    03-Jul-2020 Why do we age? What exactly is happening in our bodies? And can we do anything about it? Mankind has sought answers to these questions since time immemorial. While the pharmaceutical scientists Alexandra K. Kiemer and Jessica Hoppstädter from Saarland University are not claiming to have sol ... more

    Well shielded but highly active

    Architecture is key: Biomolecule metal–organic hybrids with high bioactivity

    03-Jul-2020 Biomacromolecules incorporated into tailored metal–organic frameworks using peptide modulators are well shielded but highly active thanks to carefully tuned nanoarchitecture. As scientists report in the journal Angewandte Chemie, this strategy can be used to synthesize an “artificial cell” ... more

    Algae as living biocatalysts for a green industry

    Discovery could lead to more environmental protection in the chemical industry

    03-Jul-2020 Many substances that we use every day only work in the right 3D structure. Natural enzymes could produce these in an environmentally friendly way – if they didn’t need a co-substrate that is expensive to produce to date. A research team at Ruhr-Universität Bochum (RUB) has discovered exactl ... more

  • People

    Cellbox Solutions Appoints Dr. Herbert Mueller-Hartmann as Head of Research and Development

    08-Jun-2020 Cellbox Solutions GmbH announces the appointment of former Head of Biosolutions R&D from Lonza Pharma and Biotech, Dr. Herbert A. Mueller-Hartmann, as the new Head of Research and Development. Dr. Mueller-Hartmann will be continuing on the successful work of Dr. Hans-Otto Nagels. Wolfgang K ... more

    2020 Eppendorf Award for Young European Investigators Goes to Randall Platt

    Prize Ceremony Postponed to 2021 in Response to COVID-19 Outbreak

    01-Apr-2020 In 2020, Eppendorf AG, the Hamburg life science company is presenting its highly prestigious research prize for the 25th time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn selected Prof. Dr. Randall J. Platt, Assistant Professor of Biological Engineering, ETH Zurich, ... more

    QIAGEN names Thierry Bernard as Chief Executive Officer

    25-Mar-2020 QIAGEN announced that Thierry Bernard has been named Chief Executive Officer. Additionally, a Joint Meeting of the Supervisory Board and the Managing Board has resolved to propose Mr. Bernard, who has been with QIAGEN since 2015, for election as Chief Executive Officer and a Managing Direct ... more

  • Finances

    BioNTech to Raise USD 250 Million in Private Placement

    The private placement includes an investment in ordinary shares and a investment in 4-year mandatory convertible notes

    30-Jun-2020 BioNTech SE announced a private investment of USD 250 million (EUR 223 million) by Temasek and other accredited investors. The private placement includes an investment of approximately USD 139 million in ordinary shares and a USD 112 million investment in 4-year mandatory convertible notes. ... more

    Bit Bio secures $41.5 million of funding from top life sciences investors

    Bit Bio’s aim is to decode “cellular identity” in order to generate every cell type of the human body

    25-Jun-2020 Bit Bio, a Cambridge-based synthetic biology company combining data science and biology to code cells for the wellbeing of humanity, announced the close of a $41.5 million Series A investment, bringing the company’s total funding to $50 million. In a strong statement of support for the comp ... more

    German Federal Government invests 300 Million Euros in CureVac

    Federal Government will not influence corporate policy decisions

    16-Jun-2020 The German Federal Minister for Economic Affairs and Energy, Peter Altmaier, and Dietmar Hopp, SAP co-founder and co-founder of the investment company dievini Hopp BioTech holding GmbH & Co. KG, announced today that the Federal Republic of Germany will invest 300 million Euros in the biopha ... more

  • Cooperation

    Siemens and Exyte join forces to deliver integrated solutions for fast-track construction of smart biotech facilities

    Covid-19 poses major challenges for developing and mass-producing vaccines and medicines in existing production facilities

    10-Jun-2020 Siemens and Exyte join forces to offer end-to-end solutions for the biopharmaceutical industry by combining the digitalization expertise of Siemens with the innovation boost from Exyte. Against the background of the current challenges associated with the Covid-19 pandemic, pharmaceutical co ... more

    Merck and Baylor College of Medicine Collaborate to Advance a Vaccine Manufacturing Platform to Fight Covid-19

    Company will focus on process development and improvements for manufacturing Baylor’s Covid-19 vaccine candidates

    28-May-2020 Merck and Baylor College of Medicine, Houston, Texas, USA, announced an extension of their ongoing collaboration to advance a manufacturing platform to fight Covid-19, designed to accelerate transition to Phase 1 clinical trials. “Vaccine manufacturing is extremely complicated, so we are co ... more

    Evotec to collaborate with Ology Bioservices on antibodies against Coronavirus

    Antibodies were generated from convalescing COVID-19 patients

    04-May-2020 Evotec SE announced that its Seattle-based subsidiary Just – Evotec Biologics, Inc. has entered into a partnership with Ology Bioservices, Inc. (Ology Bio) for the evaluation and analytical characterisation of antibodies against SARS-CoV-2. This work falls under a contract awarded to Ology ... more

  • Technology

    Domain Therapeutics is granted European and US patent for biosensors assessing GPCR trafficking

    05-Feb-2020 Domain Therapeutics announced that it has been granted a patent in the US and in Europe covering a novel family of biosensors.   The patent, entitled ‘Biosensors for monitoring biomolecule localization and trafficking in cells’, was initially filed by Prof. Michel Bouvier and his team and i ... more

    Printing nanoparticle shapes for medical applications

    18-Apr-2019 Personal drug delivery or nano-robotic systems could be a key concept for future medical applications. In this context, scientists around David Ng (Department of Prof. Tanja Weil) of the Max Planck Institute for Polymer Research (MPI-P) have recently developed a technology to customize the ... more

    BioMCN to produce renewable methanol with green hydrogen

    27-Feb-2019 Nouryon (formerly AkzoNobel Specialty Chemicals) and Gasunie have agreed to supply green hydrogen to BioMCN for the production of renewable methanol from CO2. The companies say it marks the next step in the sustainability of processes in the industry. Nouryon and Gasunie are currently inves ... more

  • Laws

    Japan and Singapore Grant CRISPR Patents to Merck

    27-Nov-2019 Merck announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide. “Paired nickases represent a significant step in incre ... more

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    Merck Awarded Canadian CRISPR Nickase Patent for Foundational Genome-Editing Technology

    05-Mar-2019 Merck announced that the Canadian Patent Office has allowed Merck’s patent application directed to the use of paired CRISPR nickases in eukaryotic cells. The patent provides an important and more specific solution for scientists who need accurate methods when developing treatments for diffi ... more

  • Market

    Many of the deadliest cancers receive the least amount of research funding

    'Embarrassing' or stigmatized cancers like lung and liver are underfunded

    23-Jul-2019 Many of the deadliest or most common cancers get the least amount of nonprofit research funding, according to a new Northwestern Medicine study that examined the distribution of nonprofit research funding in 2015 across cancer types. Colon, endometrial, liver and bile duct, cervical, ovaria ... more

    Gene Editing Tools Gain an Uptick in Sales With Emphasis on Rare Genetic Disorder Management

    22-Jul-2019 According to latest research by FMI, the global gene editing tools market is estimated to have accounted for more than US$ 258 Mn in terms of value in 2018. The report on the gene editing tools market further projects that the gene editing tools market is likely to grow at a CAGR of over 18 ... more

    Merck announces the winners of its Advance Biotech Grant program

    Merck Awards Grants to Biotechs Focused on Traumatic Brain Injury, Vaccine Development and Chronic Pain

    31-May-2019 Merck announced the winners of its Advance Biotech Grant program in North America during its Biotech Start-up Summit at the Cambridge Innovation Center (Massachusetts, U.S.). The grant is given to small- and mid-size biotechnology companies that need funding and expertise to get their thera ... more

  • Politics

    Restriction of hazardous substances in tattoo inks

    15-Mar-2019 ECHA’s Committee for Socio-economic Analysis (SEAC) adopted its final opinion supporting the proposal by Denmark, Italy, Norway and ECHA to restrict the placing on the market of tattoo inks and permanent make-up. Substances within the scope of the restriction include carcinogenic, mutagenic ... more

    ECETOC Task Force provides new insights

    Toxicity testing of microparticles and poorly soluble liquids in the water environment

    15-Jan-2019 A Task Force set up by the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has provided new insights into scientific testing for the impact of undissolved particles in the aquatic environment. ECETOC launched the Task Force in response to increasing concerns among the ... more

    15 emerging technologies that could reduce global catastrophic biological risks

    11-Oct-2018 Strategic investment in 15 promising technologies could help make the world better prepared and equipped to prevent future infectious disease outbreaks from becoming catastrophic events. This subset of emerging technologies and their potential application are the focus of a new report, Tech ... more

  • Manufacturing

    Fujifilm to invest 928 million USD to expand its large scale biologics production facility in Denmark

    Doubling the drug substance production capacity

    15-Jun-2020 FUJIFILM Corporation will make a major capital investment of approximately 100 billion yen (928 million USD) in the Denmark site of FUJIFILM Diosynth Biotechnologies, a leading contract development and manufacturing organization (CDMO) for biologics and advanced therapies. The capital inves ... more

    WITec Begins Expansion of its Headquarters Facility

    Increased capacity required to meet growing demand for Raman imaging microscopes

    12-Jun-2020 WITec GmbH is expanding its headquarters building in Ulm. The new addition will offer more space for production and quality assurance, laboratories for development and customer demonstrations or sample measurements, larger conference rooms and greater logistical capability. When complete, t ... more

    Eppendorf significantly expands capacities for the production of consumables

    Strong capacity expansion by 30 percent from 2021

    15-May-2020 The Eppendorf Group is expanding its production capacity at the Oldenburg in Holstein site in Germany by building two additional production halls. As a result, Eppendorf Polymere GmbH, a wholly owned subsidiary ofEppendorf AG, will increase its total capacity by around 30 percent from 2021. ... more

  • Career

    Eppendorf with worldwide setting program

    Around 250 vacancies at all locations by the end of 2019

    26-Apr-2019 The Eppendorf Group is creating around 250 new jobs worldwide this year. A large proportion of the new jobs will be created in Hamburg at the headquarters of the globally active life sciences company and is an important component of Eppendorf's growth strategy. "Eppendorf is growing strongl ... more

    Lower pension, shorter life

    12-Apr-2019 Income and social status have an increasing effect on life expectancy in Germany. On average, men with very low retirement pay die five years earlier than those who are much better off. Poverty shortens life. According to a study by researchers at the Max Planck Institute for Demographic Re ... more

    KNAUER among the top one percent of employers in Germany

    28-Feb-2019 In the study "Leading Employers Germany 2019", the Berlin-based manufacturer of high-tech laboratory measuring instruments KNAUER was ranked as one of the best employers for the second time. This makes KNAUER one of the companies with the best ratings in an independent meta-study conducted ... more

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