Mettler Toledo GmbH

Success with serial dilutions depends strongly on many factors

Success with serial dilutions depends strongly on many factors

Master your serial dilution error-free for almost any protocol with the help of this guideline.

Preventive maintenance ensures productive and accurate equipment performance

Preventive maintenance ensures productive and accurate equipment performance

When economic pressures take a toll on a company, often decision makers will cut back on activities that are believed to be non-essential

A Fast Routine Test – Ensures Trusted Moisture Results

A Fast Routine Test – Ensures Trusted Moisture Results

Regular verification of measuring devices is essential to ensure valid results and maintain quality

Minimized user exposure with safe powder dispensing

Minimized user exposure with safe powder dispensing

This application note explains how the XPR Automatic Balance can significantly reduce exposure risk during automated powder and liquid dispensing.

Accurate preparation of standards for chromatographic analysis

Accurate preparation of standards for chromatographic analysis

The method presented enables using less substance and solvent, ultimately significantly saving time and money

Management of weighing data – From paper to digital

Management of weighing data – From paper to digital

Pros and cons of different levels of weighing data management and possibilities of optimizing the integration of weighing data

How to enhance lab safety by lean principles

How to enhance lab safety by lean principles

The lean method known as "5S +1" not only improves process efficiency and analytical quality, but also safety.

Guide to moisture analysis

Guide to moisture analysis

This guide to moisture analysis assists you in determining reliably the moisture content with a halogen moisture analyzer.

Correct Test Weight Handling Guide: 12 Practical Tips

Correct Test Weight Handling Guide: 12 Practical Tips

Weights are the most frequently used and most important equipment for testing scales and balances

Benefits of automated capsule filling

Benefits of automated capsule filling

Automating the process of capsule filling can significantly improve both productivity and safety, allowing for great time savings.

Weighing the right way

Weighing the right way

The purpose of this guide is to identify most common factors affecting weighing accuracy and to explain the basic rules of weighing the right way.

How to ensure accurate weighing results every day?

How to ensure accurate weighing results every day?

Routine testing of balances and scales by the user is essential to uncover malfunctions early and eliminate inaccuracies.

Lactose Monohydrate Moisture Content Determination

Lactose Monohydrate Moisture Content Determination

This application note describes how METTLER TOLEDO's halogen moisture analyzer can be used to determine the moisture content in lactose monohydrate.

Don't let static charges disrupt your weighing accuracy

Don't let static charges disrupt your weighing accuracy

Understanding what causes electrostatic charges during weighing, and how to avoid or eliminate them, is critical to avoiding disruption to weighing processes.

Guide to balance cleaning: 8 simple steps

Guide to balance cleaning: 8 simple steps

A clean laboratory has a significant impact on both operator safety and cross-contamination risk

Stay Safe When Weighing

Stay Safe When Weighing

This paper describes 13 steps for safe, accurate weighing in safety cabinets or other enclosures.

UV/Vis Application in COVID-19 Vaccine Research

UV/Vis Application in COVID-19 Vaccine Research

A vaccine is a type of treatment aimed at stimulating the body’s immune system to fight against infectious pathogens such as bacteria and viruses. The

How to quickly check pipettes?

How to quickly check pipettes?

Are you planning an important experiment, perhaps with rare or precious substances? Do you need to ensure that the pipette used measures correctly?

Worry-Free Weighing — Our Medicine for Optimized Processes

Worry-Free Weighing — Our Medicine for Optimized Processes

Find valuable tips and tricks on how to optimize your weighing workflows in the new weighing guide

Data Integrity Presents Challenges Everywhere

Data Integrity Presents Challenges Everywhere

Data Integrity ALCOA defines a framework to achieve data integrity, especially important for regulated industries.

Weighing in Pharmaceutical Quality Control according to U.S. Pharmacopeia

Weighing in Pharmaceutical Quality Control according to U.S. Pharmacopeia

USP Chapter 41 weighing requirements are mandatory in a Pharmaceutical Quality Control laboratory, where weighing is a fundamental step.

Because in laboratory safety comes first

Because in laboratory safety comes first

Every job has its own health and safety risks.It's up to us to do our part to avoid any accidents

Essential Laboratory Skills Guide

Essential Laboratory Skills Guide

This "Essential Laboratory Skills" Guide supports lab operators to recognize and avoid potential error sources and ultimately increase laboratory efficiency.

ETC Powder Dispensing Study

ETC Powder Dispensing Study

Can an automated powder dosing solution in the pharmaceutical industry meet the re-quirements of applications, and which system is best suited?

Moisture methods for pharmaceutical excipients

Moisture methods for pharmaceutical excipients

This Collection of Moisture Analyzer Methods for Pharmaceutical Industry features moisture methods for pharmaceutical excipients developed by Mettler Toledo.

Life Science Toolbox for UV/VIS Spectroscopy

Life Science Toolbox for UV/VIS Spectroscopy

UV/VIS Spectrophotometry has become a standard method used on a daily basis in many life science laboratories

How to achieve and maintain pharmaceutical compliance

How to achieve and maintain pharmaceutical compliance

The new Pharmaceutical Compliance Guide discusses strategies and solutions to help pharmaceutical laboratories with compliance.

Spectrophotometry applications and fundamentals

Spectrophotometry applications and fundamentals

Provides the reader with fundamental knowledge on this technique as well as spectrophotometry applications, and tips and tricks for accurate results

Worry-free Weighing - Our Medicine for Optimized Processes

Worry-free Weighing - Our Medicine for Optimized Processes

Identification of inefficiencies and specific bottlenecks in weighing is key to optimize laboratory processes and performance.

Automated Powder Dispensing for Pharma & Biotech

Automated Powder Dispensing for Pharma & Biotech

Automated Powder dispensing for pharma and biotech R&D can increase efficiency in high-throughput applications, such as screening and formulation.

Safe Weighing Range Ensures Accurate Results

Safe Weighing Range Ensures Accurate Results

Weighing in the safe weighing range ensures results are valid, reliable and right the first time.

8 Wastes of Lean Laboratory - Checklist

8 Wastes of Lean Laboratory - Checklist

8 wastes of Lean Laboratory identification checklist is a simple way to audit the efficiency of your laboratory.

UV/VIS Spectrophotometry Applications for Life Science in a Nutshell

UV/VIS Spectrophotometry Applications for Life Science in a Nutshell

The UV/VIS Life Science Applications guide deepens into the most common applications in the field of Life Science

Semi-Automated Pipetting

Semi-Automated Pipetting

BenchSmart 96 is a semi-automated manual pipetting system with electronic functionality for 96- and 384-well plate assays

Good Pipetting Practice

Good Pipetting Practice

GPP (Good Pipetting Practice) presents a comprehensive and systematic approach to optimizing pipetting accuracy and repeatability

Accreditation to an International Standard

Accreditation to an International Standard

IS0 15198 changes the servicing requirements for laboratory equipment used in medical laboratories

High-Throughput FPLC in a Packed Resin Tip

High-Throughput FPLC in a Packed Resin Tip

The novel patented PureSpeed tip technology for high throughput protein affinity chromatography enables efficient and effective purification workflow

Biochemical Oxygen Demand

Biochemical Oxygen Demand

One important analysis to assess water quality is determining the BOD (biochemical oxygen demand)

The Characterization of Pharmaceuticals Using Thermal Analysis

The Characterization of Pharmaceuticals Using Thermal Analysis

The guide was designed to support thermal analysis (TA) users with real examples of the most relevant applications pertinent to the pharmaceutical industry

Optimizing Protein Purification Conditions

Optimizing Protein Purification Conditions

PureSpeed Protein Tips have been demonstrated to be the most efficient and cost-effective way to purify recombinant proteins and antibodies

Pipetting Toolbox for Life Sciences

Pipetting Toolbox for Life Sciences

The use of pipettes to transfer liquids is a daily activity in most life science research labs

CCDB Simplifies Genomic Workflow, DNA Barcoding

CCDB Simplifies Genomic Workflow, DNA Barcoding

Biological research is increasingly reliant on the ability of researchers to collect data from large numbers of samples

Improving Quantitative ELISA Data

Improving Quantitative ELISA Data

Liquidator 96 delivers both speed and high data quality to ELISA and other assays

Positive Displacement Pipetting

Positive Displacement Pipetting

Positive displacement pipettes are important players in the laboratory liquid handling toolbox

Counteracting Liquid Retention in Tips

Counteracting Liquid Retention in Tips

Download the white paper for the full analysis of the effects of Rainin LR tips on pipetting various surfactants

Pipette Tip Quality

Pipette Tip Quality

To produce reliable experimental results, pipette tip selection should be prioritized alongside technique and pipette calibration

Wavelength Accuracy in UV/VIS Spectrophotometry

Wavelength Accuracy in UV/VIS Spectrophotometry

Wavelength accuracy and repeatability are key performance aspects of UV/VIS instruments

Automated Performance Verification

Automated Performance Verification

Performance verification is essential to ensure accurate and reliable instrument performance

Temperature Control for UV/VIS Spectrophotometry

Temperature Control for UV/VIS Spectrophotometry

Temperature control is an important parameter in many UV/VIS Spectroscopy applications, especially for temperature-sensitive organic samples

Stray Light and Performance Verification

Stray Light and Performance Verification

Stray light is one of the most important factors which can influence photometric accuracy and precision

pH Toolbox for Life Sciences

pH Toolbox for Life Sciences

Our pH Toolbox for Life Sciences supports you in selecting, calibrating and operating the right sensor and meter

Basics of Titration

Basics of Titration

Titration is an analytical technique which allows the quantitative determination of a specific substance dissolved in a sample

pH Theory Guide

pH Theory Guide

The control and measurement of pH is vital in a wide range of processes across the pharmaceutical, chemical, and food & beverage industries

How to Measure pH in Protein-Containing Samples

How to Measure pH in Protein-Containing Samples

In order to obtain accurate pH readings, the pH sensor must be maintained in optimal condition

How to Measure pH In TRIS-Containing Samples

How to Measure pH In TRIS-Containing Samples

TRIS buffers, which are often present in biological samples, can cause challenges in pH measurement

How to Measure pH in Small Samples

How to Measure pH in Small Samples

With the right pH micro sensor it is possible to minimize sample size and sample manipulation to achieve accurate pH measurement results

Get our Weighing Guide

Get our Weighing Guide

Preparation of buffers, standards and samples often requires weighing followed by dissolution to a defined volume or dilution in volumetric flasks

No Weighing with a Blocked Balance

No Weighing with a Blocked Balance

All balances undergo a monthly repeatability test in accordance with U.S. Pharmacopeia

Getting Weighing Right — The Importance of Leveling

Getting Weighing Right — The Importance of Leveling

Ensuring that a balance is level is crucial to obtaining accurate weighing results

Eliminating Weighing Uncertainty Adds Confidence to Manufacturing Process

Eliminating Weighing Uncertainty Adds Confidence to Manufacturing Process

The industrial scale plays a critical role in many manufacturing facilities

Daily Sensitivity Test

Daily Sensitivity Test

As is the case for a number of other businesses, the pharmaceutical industry tends to have strictly regulated areas, for example in quality control procedures

From Paper to Digital - Management of Weighing Data

From Paper to Digital - Management of Weighing Data

Learn more about pros and cons of different levels of weighing data management, as well as tips how to optimize the integration of your weighing data

How to Reduce Uncertainty in Weighing?

How to Reduce Uncertainty in Weighing?

In weighing accuracy is everything. Every little thing matters.

Start your workflow optimization now!

Start your workflow optimization now!

In this weighing guide, you get a detailed overview and advice on how to optimize weighing workflows the pharmaceutical industry.

Uninterrupted Testing During Weight Recertification

Uninterrupted Testing During Weight Recertification

Businesses that utilize quality assurance systems such as GMP/GLP must check their balances regularly. The check intervals are often very short.

Quality Improvements in Weighing Via Process Tolerance and Safety Factor

Quality Improvements in Weighing Via Process Tolerance and Safety Factor

When weighing is used in production, significant quality improvements are made possible by managing weighing process tolerances.

What is the Correct Way to Check Repeatability in Balances?

What is the Correct Way to Check Repeatability in Balances?

Your balance must provide the same result for repeated weighing of the same load under the same measurement conditions.

12 Free Tips Help Keep Test Weights Accurate

12 Free Tips Help Keep Test Weights Accurate

How you handle test weights can make a big difference in their accuracy. The reference article contains 12 important cleaning and storage suggestions.

GWP - The Science Based Global Standard

GWP - The Science Based Global Standard

GWP® ensures efficient weighing lifecycle management, with advice on balance selection, calibration and routine testing.

Gravimetric sample preparation – reducing sample size and OOS errors

Gravimetric sample preparation – reducing sample size and OOS errors

Over 50% of out-of-specification (OOS) results in analytical workflows are reportedly caused by sample processing and operator errors

The Unknown Sources of Error in the Weighing Process

The Unknown Sources of Error in the Weighing Process

Data integrity, quality and efficiency can be improved by eliminating potential error sources in the weighing process.

Outstanding Weighing Performance – Even under Harsh Conditions

Outstanding Weighing Performance – Even under Harsh Conditions

Weighing is one of the most common activities carried out in the laboratory. An electronic balance does not directly measure a mass, rather the force

An Unseen Force May Be Disrupting Your Weighing: Learn 13 Ways to Stop It

An Unseen Force May Be Disrupting Your Weighing: Learn 13 Ways to Stop It

Built-up electrostatic charges can change how a balance registers weight—and the effect can be particularly damaging when working with powdered substances.

Optimizing workplaces and workflows

Optimizing workplaces and workflows

The successful implementation of 'Lean Manufacturing' in several fields has inspired many businesses to adopt this model in laboratories as well.