Bioreactor control system for precise fermentation in biopharma applications

Bioreactor control system with gravimetric feed is an efficient method for precise fermentation in biopharma applications. With the increasing need for accurate and consistent fermentation processes in the biopharmaceutical industry, the need for rapid, simple, compliant, and cost-efficient bioreactor process control becomes a key factor for success. A bioreactor feed control system based on adding liquids by weight rather than by volume is a proven method that ensures highly precise fermentation.

This application note outlines how Mettler-Toledo precision balances can control the flow of liquids into a bioreactor in a simple control loop involving the bioreactor, the pump and the balance. This control loop is established via seamless integration among the instruments. With gravimetric feed control using a balance, you can be sure of efficient, accurate, and reliable process control with a minimum amount of investment – resulting in more efficient research and development processes.