Raman spectroscopic mapping for the analysis of solar radiation induced skin damage
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Working with an artificial skin model exposed to simulated solar irradiation, scientists in Ireland used Raman spectroscopic mapping to identify the dermal and stratum corneum layers in samples and distinguish further substructures of the epidermis.
The authors were able to identify DNA damage, loss of lipidic signatures and changes in protein signatures and track trends in these changes according to the exposure times of the samples. The authors state that ‘Raman spectroscopy can identify a significant degree of biochemical damage at stages where minimal loss in tissue viability is observed, suggesting the modality holds great potential for early disease diagnosis.’