Gentle protein purification at the touch of a button
i3 Membrane revolutionizes the separation of biological agents
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chromatography is a key process in biotechnology, particularly in the analysis and production of modern active ingredients for antibody-based therapies and gene therapies. The active ingredients are bound to special surfaces (with ion exchange or affinity ligands), while unwanted substances are rinsed out of the production process. To release the valuable proteins again, the use of acids and complex additional steps has been necessary until now - with the risk of damaging some of the sensitive molecules.
This is where Digital Membrane Chromatography, developed by i3 Membrane, comes in and transforms the process: instead of acid, a low electrical voltage of up to 2 volts is used to gently release proteins such as monoclonal or bispecific antibodies and ADCs from the surfaces. The process enables gentle and rapid purification as well as direct further use of the proteins in the appropriate solution - at the touch of a button.
"With DMC, we are taking chromatography to a new level and simultaneously leading it into the digital age. Our first products are not only innovative - they are real game changers for anyone working with proteins," emphasizes Dr. Stephan Brinke-Seiferth, CEO of i3 Membrane GmbH. "Researchers and pharmaceutical companies save time, protect their molecules and open up completely new analytical possibilities."
With the market launch of the world's first adsorber for digital membrane chromatography (DMC), i3 Membrane GmbH is opening up completely new horizons in protein analysis and bioprocess development.
Note: This article has been translated using a computer system without human intervention. LUMITOS offers these automatic translations to present a wider range of current news. Since this article has been translated with automatic translation, it is possible that it contains errors in vocabulary, syntax or grammar. The original article in German can be found here.
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Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!
Topic World Chromatography
Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!
Topic world Protein analytics
Protein analytics provides a deep insight into these complex macromolecules, their structure, function and interactions. It is essential for discovering and developing biopharmaceuticals, understanding disease mechanisms, and identifying therapeutic targets. Techniques such as mass spectrometry, Western blot and immunoassays allow researchers to characterize proteins at the molecular level, determine their concentration and identify possible modifications.
Topic world Protein analytics
Protein analytics provides a deep insight into these complex macromolecules, their structure, function and interactions. It is essential for discovering and developing biopharmaceuticals, understanding disease mechanisms, and identifying therapeutic targets. Techniques such as mass spectrometry, Western blot and immunoassays allow researchers to characterize proteins at the molecular level, determine their concentration and identify possible modifications.