My watch list
my.bionity.com  
Login  

New Method to Create Ultrafast 3D Images of Nanostructures

Protein structures of viruses can be analysed much faster

18-Apr-2019

Lensless microscopy with X-rays, or coherent diffractive imaging, is a promising approach. It allows researchers to analyse complex three-dimensional structures, which frequently exist in nature, from a dynamic perspective. Whilst two-dimensional images can already be generated quickly and in an efficient manner, creating 3D images still presents a challenge. Generally, three-dimensional images of an object are computed from hundreds of individual images. This takes a significant amount of time, as well as large amounts of data and high radiation values.

A team of researchers from Leibniz University Hannover and other universities has now succeeded in accelerating this process considerably. The researchers developed a method in which two images of an object can be taken from two different directions using a single laser pulse. The images are then combined to form a spatial image – similar to the human brain forming a stereo image from two slightly different images of both eyes. The method of computer-assisted stereoscopic vision is already used in the fields of machine vision and robotics. Now researchers have used the method in X-ray imaging for the first time.

“Our method enables 3D reconstructions on a nanometric scale using a single image which consists of two images from two different perspectives”, says Professor Milutin Kovacev from the Institute of Quantum Optics at Leibniz University Hannover, who is one of the co-authors of the study.

According to the authors, the method will have a significant impact on 3D structural imaging of individual macromolecules and could be used in biology, medicine, as well as in the industry. For example, the protein structure of a virus could be analysed faster and with very little effort. The protein structure has an immense influence on the function and behaviour of a virus and plays a decisive role in medical diagnoses.

Facts, background information, dossiers
More about Uni Hannover
  • News

    Eliminating hepatitis C viruses effectively

    The treatment of hepatitis C has been based on specific effective antiviral medications for a number of years. Since future development of resistance cannot be ruled out, alternative treatment options are being researched as well. So-called cell entry inhibitors are considered to be promisi ... more

    Nanotechnology with proteins

    For over two decades, scientists have been using DNA to design nanomaterials. Researchers from the University of Göttingen and the Medical School Hanover, both in Germany, have now discovered a new method to use proteins to construct two-dimensional webbings. The use of proteins in nanotech ... more

    Could your smartphone one day tell you you're pregnant?

    Researchers at the Hanover Centre for Optical Technologies (HOT), University of Hanover, Germany, have developed a self-contained fiber optic sensor for smartphones with the potential for use in a wide variety of biomolecular tests, including those for detecting pregnancy or monitoring diab ... more

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE