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Tuberoinfundibular pathway



The tuberoinfundibular pathway refers to a population of dopamine neurons in the arcuate nucleus of the mediobasal hypothalamus (the 'tuberal region') that project to the median eminence (the 'infundibular region'). It is one of the four major dopamine pathways in the brain. Dopamine released at this site regulates the secretion of prolactin from the anterior pituitary gland.

Additional recommended knowledge

Some antipsychotic drugs block dopamine in the tuberoinfundibular pathway, which can cause an increase in blood prolactin levels (hyperprolactinemia). This can cause abnormal lactation (even in men), disruptions to the menstrual cycle in women, visual problems, headache and sexual dysfunction.


Other major dopamine pathways include:

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tuberoinfundibular_pathway". A list of authors is available in Wikipedia.
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