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Boutonneuse fever

Boutonneuse fever
Classification & external resources
ICD-10 A77.1
ICD-9 082.1
DiseasesDB 31780
MeSH D001907

Boutonneuse fever (also called Mediterranean spotted fever, fièvre boutonneuse, or Marseilles fever) is a fever as a result of a Rickettsial infection caused by the bacterium Rickettsia conorii and transmitted by the dog tick Rhipicephalus sanguineus. Boutonneuse fever is endemic in many countries surrounding the Mediterranean Sea.



After an incubation period of around seven days, the disease manifests abruptly with chills, high fevers, muscular and articular pains, severe headache and photophobia. The location of the bite forms a black crust (tache noire). Around the fourth day of the illness an exanthem (widespread rash) appears, first macular and then maculopapular and sometimes petechial.


The diagnosis is made with serologic methods, either the classic Weill Felix test (agglutination of Proteus OX strains ), either ELISA or immunofluorescence assays.


The illness is treated with chloramphenicol or doxycycline.

See also

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Boutonneuse_fever". A list of authors is available in Wikipedia.
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