Zidovudine

Generics are predicted to take over the antiviral drugs market, especially in the case of HIV medication, as a series of patent expiries will open opportunities for ambitious companies to seize huge revenue, according to a new report by healthcare experts GBI Research.The new report, "Generics in th more

Chemists at UC San Diego and statisticians at Harvard University have developed a novel way to trace mutations in HIV that lead to drug resistance. Their findings, once expanded to the full range of drugs available to treat the infection, would allow doctors to tailor drug cocktails to the particula more

Gilead Sciences, Inc. announced that the company has entered into a licensing agreement with Japan Tobacco Inc. (JT) under which JT will commercialize products in Gilead's HIV portfolio in Japan. The agreement includes Viread® (tenofovir disoproxil fumarate), EmtrivaTM (emtricitabine) and a future c more

Publication date: 15 September 2018 Source:European Journal of Pharmaceutical Sciences, Volume 122 Author(s): S.M.T. Cavalcanti, C. Nunes, S.A. Costa Lima, J.L. Soares-Sobrinho, S. Reis An adapted methodology for obtaining lipid nanoparticles that only uses the microwave reactor in t more

Abstract Considering a novel series of zidovudine (AZT) derivatives encompassing selenoaryl moieties promising candidates as therapeutics, we examined the toxicities elicited by AZT and derivatives 5′-(4-Chlorophenylseleno)zidovudine (SZ1); 5′-(Phenylseleno)zidovudine (SZ2); and 5′-(4-Methylphenyls more

by Gbolahan Ajibola, Rebecca Zash, Roger L. Shapiro, Oganne Batlang, Kerapetse Botebele, Kara Bennett, Florence Chilisa, Erik von Widenfelt, Joseph Makhema, Shahin Lockman, Lewis B. Holmes, Kathleen M Powis Introduction A large and increasing number of HIV-infected women are conceiving on antiret more