BioTrove Announces R&D Collaboration with Constellation Pharmaceuticals

13-Nov-2008 - USA

BioTrove, Inc. announced it has formed a research collaboration with Constellation Pharmaceuticals in which Constellation will utilize BioTrove's RapidFire® mass spectrometry (RF-MS) system to accelerate development of novel therapeutics in the emerging field of epigenetics.

Constellation was founded in April of 2008 as the first biopharmaceutical company focused on discovering and developing novel drugs targeting selective regulators of epigenetic function through a $32 million Series A financing led by Third Rock Ventures, The Column Group and Venrock.

Constellation researchers will use BioTrove's RapidFire screening and analysis system to explore a new class of drugs regulating the epigenome to alter gene expression by manipulation of chromatin's histone proteins. Slight modifications in protein structure are difficult to identify using conventional screening methods; however, RapidFire technology provides label-free, biologically relevant data so that researchers can determine which compounds may be validated or compromised before further investigation, according to the company. Compressing the time to develop assays for this unique class of targets will enable Constellation to screen its novel epigenetic drug candidates more efficiently and effectively than current available technologies.

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Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

1 products
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