Horizon Discovery Group plc, Centre for Process Innovation and University of Manchester Awarded £1.67M
Consortium to receive funding to develop enhanced biomanufacturing platforms based on the Company’s CHO cell line and gene editing platform
This funding will support the development of a commercially valuable enhancement to Chinese Hamster Ovary (CHO) cell lines, critical tools for biomanufacturing of high value biopharmaceuticals.
The project aims to develop a suite of engineered CHO cell lines containing a range of modifications designed to control and improve metabolic performance of these cells for the production of biological medicines. By focusing on combinatorial gene editing, the consortium aims to generate robust phenotypes, which will not only enhance understanding of the CHO expression platform, but will ultimately lead to successful industrial translation. The project is designed to decrease the risk associated with the introduction of high levels of innovation in cell line engineering, while establishing a platform that can be made broadly accessible across the biopharmaceutical industry, in the UK and beyond.
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Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.
Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.