Silence Therapeutics Forms Scientific Advisory Board

23-Mar-2012 - United Kingdom

Silence Therapeutics plc announced the creation of a Scientific Advisory Board (SAB) with the appointment of two Key Opinion Leaders (KOLs) in the area of liver disease, Professor Dr. Dr. Detlef Schuppan, M.D., PhD., and Professor Dr. Massimo Pinzani, M.D., PhD., F.R.C.P. The SAB will provide scientific perspectives and strategic insight to enable Silence to leverage its gene silencing technologies AtuRNAi and its liver specific liposome delivery technology DBTC, in the liver disease arena.

Professor Schuppan and Professor Pinzani will also collaborate with Silence in hepatocellular carcinoma (HCC) and liver fibrosis with the aim to produce a development pipeline at Silence that specifically targets these disease areas.

Professor Detlef Schuppan is a consultant Gastroenterologist and Hepatologist and Director of Molecular and Translational Medicine and full Professor of Medicine at Mainz University Medical Centre in Germany. He is also Professor of Medicine and Senior Visiting Scientist at Harvard Medical School. Professor Schuppan has been Principal and Co-Investigator in numerous clinical studies that deal with acute and chronic liver diseases, gastrointestinal (GI) cancers and with celiac disease and has published more than 350 Pubmed cited articles and 50 book chapters.

Professor Massimo Pinzani is one of the thought leaders in chronic fibrogenic disorders and particularly hepatic fibrogenesis. He is currently Professor of Medicine and Gastroenterology at the University of Florence, Italy. He is also visiting Professor in the Division of Hepatology at Osaka City School of Medicine, Japan and Adjunct Professor of Gastroenterology and Hepatology at Case Western Reserve University.

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