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The zona pellucida (or zona striata in older texts) is a glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it.
The zona glycoprotein, ZP3, is responsible for sperm binding, adhering to proteins on the sperm plasma membrane. There is evidence that ZP3 is then involved in the induction of the acrosome reaction, whereby a spermatozoon releases the contents of the acrosomal vesicle.
Additional recommended knowledge
Function in humans
Glycoproteins in ZP1, 2, and 3 are targets for immunocontraception.
In non-mammalian animals, the zona pellucida (called vitelline layer) plays an important role in preventing breeding of different species, especially in species that fertilize outside of the body (e.g. fish).
The zona pellucida is commonly used to control wildlife population problems by immunocontraception. When the zona pellucida of one animal species is injected into the bloodstream of another, it results in sterility of the second species due to immune response. This effect can be temporary or permanent, depending on the method used. In New Jersey, Porcine zona pellucida is used to keep deer populations low, and this process is commonly referred to as "spay-vac".
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Zona_pellucida". A list of authors is available in Wikipedia.|