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Hydrolase



In biochemistry, a hydrolase is an enzyme that catalyzes the hydrolysis of a chemical bond. For example, an enzyme that catalyzed the following reaction is a hydrolase:

A–B + H2O → A–OH + B–H

Additional recommended knowledge

Nomenclature

Systematic names of hydrolases are formed as "substrate hydrolase." However, common names are typically in the form "substratease." For example, a nuclease is a hydrolase that cleaves nucleic acids.

Classification

Hydrolases are classified as EC 3 in the EC number classification of enzymes. Hydrolases can be further classified into several subclasses, based upon the bonds they act upon:

References

  • EC 3 Introduction from the Department of Chemistry at Queen Mary, University of London, only covers 3.1-3.4
  • More detailed taxonomy
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hydrolase". A list of authors is available in Wikipedia.
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