Molecular Devices, LLC announced a partnership with Cytena GmbH to launch the CloneSelect™ Single-Cell Printer™ in North America. This system utilizes microfluidics-based technology and real-time image analysis to isolate single cells and provide visual documentation of monoclonality for use in cell line development.
Clonal cell line development has been receiving increasing focus and investment as a method for producing targeted therapeutics. As a part of the development process, cells producing high amounts of the antibody of interest need to be selectively isolated to be able to move them forward for additional screening. The CloneSelect SCP accelerates antibody discovery by allowing for automated isolation of single cells for a wide range of cell types.
“We are very excited about this product and how it allows us to expand our toolset in the fast-growing biotherapeutics market,” said Greg Milosevich, President at Molecular Devices. “Our customers have been seeking ways to bring biologics and biosimilars to market more quickly, and we continue to invest in technologies that accelerate time-consuming process steps.”
Traditional methods for single cell sorting in cell line development suffer from drawbacks including low sorting efficiencies, low cell viabilities, and limited evidence of monoclonality. The CloneSelect SCP overcomes these limitations by screening for both single cells and for cell morphology immediately prior to gently depositing in the well, ensuring high cell viability. The use of sterilized, disposable cartridges also ensures the prevention of any cross-contamination or need for in-situ sterilization. During deposition, images of single cells are provided, giving customers the confidence of knowing their cell lines are monoclonal.
“This partnership will accelerate the continued growth of our business,” said Jonas Schoendube, CEO at Cytena. “We are looking forward to having additional commercial capabilities in the United States and Canada as a result of our work with Molecular Devices, and we believe that this relationship will bring superior service to our customer base.”