Yabao Pharmaceuticals Enters Partnership with Eli Lilly and Company to Develop Diabetes Treatment

08-Jul-2014 - China

Yabao Pharmaceutical Co, Inc.  announced a strategic partnership with Eli Lilly and Company to co-develop Lilly's leading glucokinase activator (GKA), LY2608204. Lilly's GKA has completed Phase 1 studies in the US in addition to extensive pre-clinical development.

Diabetes is a disease of great unmet need in China and worldwide. Glucokinase activators have the potential to differentiate from other anti-diabetic agents by exerting two potentially beneficial actions: promoting insulin secretion and decreasing glucose production by the liver. As a result, glucokinase activators may exert powerful anti-hyperglycemic effects, even in patients who are relatively unresponsive to other oral drugs.

Under the terms of the agreement, Yabao receives rights to develop and commercialize the GKA compound in China while Lilly retains rights in all other markets. The parties will collaborate to determine a strategic development plan for China, and Yabao will initially be responsible to perform and fund all development, with Lilly having future buy-in options for China. Financial terms were not disclosed.

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