Fourth ventricle

The fourth ventricle is one of the four connected fluid-filled cavities within the human brain. These cavities, known collectively as the ventricular system, consist of the left and right lateral ventricles, the third ventricle, and the fourth ventricle. The fourth ventricle extends from the cerebral aqueduct (aqueduct of Sylvius) to the obex, and is filled with cerebrospinal fluid (CSF).

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The fourth ventricle has a characteristic diamond shape in cross-sections of the human brain. It is located within the pons or in the upper part of the medulla. CSF entering the fourth ventricle through the cerebral aqueduct can exit to the subarachnoid space of the spinal cord through two lateral foramina of Luschka (singular: foramen of Luschka) and a single, midline foramen of Magendie (see List of human anatomical parts named after people).

Roof and floor

The fourth ventricle has a "roof" dorsally and a "floor" ventrally. The roof of the fourth ventricle is formed by the cerebellum (superior and inferior medullary velums), the floor by the rhomboid fossa, and the side "walls" formed by the cerebellar peduncles. Among the prominent features of the floor of the fourth ventricle are the:

• facial colliculus: formed by the internal part of the facial nerve as it loops around the abducens nucleus in the lower pons;
• sulcus limitans: which represents the border between the alar plate and the basal plate of the developing neural tube;
• obex: represents the caudal tip of the fourth ventricle; the obex is also a marker for the level of the foramen magnum of the skull and therefore is a marker for the imaginary dividing line between the medulla and spinal cord.

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