ProtAffin AG Granted Patent in EU for Lead Anti-inflammatory Product PA401
Whereas wild-type chemokines are over-expressed in many chronic and acute inflammatory diseases, ProtAffin has developed anti-inflammatory variants of IL-8 with increased affinity for heparin-like glycan structures found on inflamed endothelium. These anti-inflammatory products do not activate chemokine receptors found on leukocytes.
Dr. Jason Slingsby, CEO of ProtAffin commented: “We are very pleased that the European Patent Office has granted us claims protecting our lead anti-inflammatory product PA401, as well as other anti-inflammatory variants of IL-8. This is an important commercial step for us as we seek to develop and commercialise PA401 for a number of chronic and acute diseases in the world’s major pharmaceutical markets. PA401 represents a novel class of biological product which disrupts protein-glycan interactions which drive inflammation in a number of diseases with serious unmet medical need.”
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