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Innovative technology for the enrichment of free-circulating DNA

13-Jan-2014

After a two year period of development Analytik Jena has launched an innovative technology to enrich and isolate free-circulating DNA. Free-circulating DNA occurs in plasma, serum, and urine, among other things, but only in small fragments and very low concentrations. In order to isolate them, large sample volumes and large quantities of reagents had been needed until now. The kit developed by the Analytik Jena subsidiary AJ Innuscreen GmbH in Berlin is based on polymer-mediated enrichment (PME) technology. The cell-free DNA of the sample is combined with a polymer and then concentrated. The resulting DNA-polymer complex can be processed by means of a simple DNA extraction method.

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