Galapagos and Roche initiate strategic alliance in COPD

Research access payment of EUR 6 million for Galapagos

13-Jan-2010 - Belgium

Galapagos NV announced that it has entered into a global multi-year strategic alliance with Roche to develop potential new therapies in COPD (chronic obstructive pulmonary disease).

In the alliance, Galapagos will apply its target discovery platform to discover novel COPD targets. Galapagos is then responsible for the discovery and development of new small molecule candidate drugs against these targets. Roche will have an exclusive option to license each small molecule program after either clinical candidate selection or completion of Phase I clinical trials. In addition, Roche has an exclusive option to license the COPD targets for the discovery and development of antibodies against these targets. Upon exercise of each option, Roche will be responsible for the further (pre)clinical development and commercialization.

Under the terms of the agreement, Galapagos has received a research access payment of EUR 6 million from Roche. Galapagos is also eligible to receive discovery, development, regulatory and sales milestone payments that could potentially exceed EUR 400 million, plus royalties upon commercialization of any products covered in the agreement.

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Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous

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Topic world Antibodies

Topic world Antibodies

Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous