Mallory-Weiss syndrome Classification & external resources
Mallory-Weiss syndrome refers to bleeding from tears (a Mallory-Weiss tear) in the mucosa at the junction of the stomach and esophagus, usually caused by severe retching, coughing, or vomiting.
Additional recommended knowledge
It is often associated with
alcoholism and  eating disorders and there is some evidence that presence of a hiatal hernia is a required predisposing condition.
Mallory-Weiss syndrome often presents as an episode of vomiting up blood (hematemesis) after violent retching or vomiting, but may also be noticed as old blood in the stool (melena), and a history of retching may be absent.
In most cases, the bleeding stops spontaneously after 24-48 hours, but
endoscopic or surgical treatment is sometimes required and rarely the condition is fatal.
Definitive diagnosis is by
Treatment is usually supportive as persistent bleeding is uncommon. However
cauterization or injection of epinephrine to stop the bleeding may be undertaken during the index endoscopy procedure.
embolization of the arteries supplying the region may be required to stop the bleeding.
The condition was first described in 1929 by G. Kenneth Mallory and Soma Weiss in 15 alcoholic patients.
 See also
^ Caroli A, Follador R, Gobbi V, Breda P, Ricci G (1989). "[Mallory-Weiss syndrome. Personal experience and review of the literature]" (in Italian). Minerva dietologica e gastroenterologica 35 (1): 7–12. PMID 2657497.
^ Gawrieh S, Shaker R (2005). "Treatment of actively bleeding Mallory-Weiss syndrome: epinephrine injection or band ligation?". Current gastroenterology reports 7 (3): 175. PMID 15913474. Weiss S, Mallory GK. ^ Lesions of the cardiac orifice of the stomach produced by vomiting. Journal of the American Medical Association 1932;98:1353-55.
Cecil Textbook of Medicine
The Oxford Textbook of Medicine
Digestive system - Gastroenterology (primarily K20-K93, 530-579) Esophagus Esophagitis - GERD - Achalasia - Boerhaave syndrome - Nutcracker esophagus - Zenker's diverticulum - Mallory-Weiss syndrome - Barrett's esophagus Stomach/ duodenum Peptic (gastric/duodenal) ulcer - Gastritis - Gastroenteritis - Duodenitis - Dyspepsia - Pyloric stenosis - Achlorhydria - Gastroparesis - Gastroptosis - Portal hypertensive gastropathy Hernia Inguinal ( Indirect, Direct) - Femoral - Umbilical - Incisional - Diaphragmatic - Hiatus Noninfective enteritis and colitis IBD (Crohn's, Ulcerative colitis) - noninfective gastroenteritis Other intestinal vascular ( Abdominal angina, Mesenteric ischemia, Ischemic colitis, Angiodysplasia) - Ileus/ Bowel obstruction ( Intussusception, Volvulus) - Diverticulitis/ Diverticulosis - IBS other functional intestinal disorders ( Constipation, Diarrhea, Megacolon/ Toxic megacolon, Proctalgia fugax) - Anal fissure/ Anal fistula - Anal abscess - Rectal prolapse - Proctitis ( Radiation proctitis) Liver/ hepatitis Alcoholic liver disease - Liver failure ( Acute liver failure) - Cirrhosis - PBC - NASH - Fatty liver - Peliosis hepatis - Portal hypertension - Hepatorenal syndrome Accessory digestive Gallbladder ( Gallstones, Choledocholithiasis, Cholecystitis, Cholesterolosis, Rokitansky-Aschoff sinuses)
Biliary tree (Cholangitis,
Cholestasis/ Mirizzi's syndrome, PSC, Biliary fistula, Ascending cholangitis)
Pancreas ( Acute pancreatitis, Chronic pancreatitis, Pancreatic pseudocyst, Hereditary pancreatitis) Other/general Appendicitis - Peritonitis ( Spontaneous bacterial peritonitis)
Malabsorption ( celiac, Tropical sprue, Blind loop syndrome, Whipple's)
postprocedural: Gastric dumping syndrome - Postcholecystectomy syndrome
bleeding: Hematemesis - Melena - Gastrointestinal bleeding ( Upper, Lower) See also congenital