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Hemolytic disease of the newborn (anti-RhE)

HDN due to anti-RhE alloimmunization
Classification & external resources
ICD-10 P55.8
ICD-9 773.2

Hemolytic disease of the newborn (anti-RhE) is caused by the anti-RhE antibody of the Rhesus blood group system. The anti-RhE antibody can be naturally occurring, or arise following immune sensitization after a blood transfusion or pregnancy.

Additional recommended knowledge

The anti-RhE antibody is quite common especially in the Rhesus genotype CDe/CDe; it can occasionally cause mild jaundice in the neonate, but it never causes severe haemolytic disease of the newborn. It can occur with other antibodies, usually the anti-Rhc antibody, which can cause a severe hemolytic disease.


  • Antenatal & neonatal screening (second edition). Chapter 12: Rhesus and other haemolytic diseases, by E.A. Letsky, I. Leck, J.M. Bowman. 2000. Oxford University Press. ISBN 0-19-262827-7.

See also

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hemolytic_disease_of_the_newborn_(anti-RhE)". A list of authors is available in Wikipedia.
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