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Aquaporin 4



aquaporin 4
Identifiers
Symbol AQP4
Entrez 361
HUGO 637
OMIM 600308
RefSeq NM_001650
UniProt P55087
Other data
Locus Chr. 18 q11.2-12.1

Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells.

Additional recommended knowledge

AQP4 is constitutively expressed.

AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system.

Pathology

It is the autoimmune target in Devic's disease.

See also

  • Aquaporins
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Aquaporin_4". A list of authors is available in Wikipedia.
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