Cancer

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News Cancer

• How cells move and don’t get stuck
  

  Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. Cell velocity, or how fast a cell moves, is known to depend on how sticky the surface is beneath it, but the precise mechanisms of this relationship hav more

• Single-cell test can reveal precisely how drugs kill cancer cells
  

  Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D2O-probed CANcer Susceptibility Test Ramanometry (D2O-CANST-R) to see, at single-cell more

• A potent weapon against lymphomas
  

  MDC researchers have developed a new approach to CAR T-cell therapy. The team has shown in Nature Communications that the procedure is very effective, especially when it comes to fighting follicular lymphomas and chronic lymphocytic leukemia, the most common type of blood cancer in adults. The body’ more

Videos Cancer

Timing Cancer Treatment

There may be an ideal waiting period for delivering multiple cancer drugsResearchers led by members of the Department of Systems Biology at Harvard Medical School had been studying how silencing MDMX, an oncogene, affected the dynamics of p53, a natural tumor suppressor, in cancer cells when the ... more

PARP-inhibitors: A New Generation of Cancer Drugs

First of new generation of cancer drugs granted European approvalA new drug for ovarian cancer, developed by researchers at the University of Cambridge and AstraZeneca, has become the first of new class of drugs, known as PARP-inhibitors, to be granted approval anywhere in the world. The drug, L ... more

ICR Researchers use Cryo-Electron Microscopy to zoom in on DNA code being read in cells

ICR Researchers led by Dr Alessandro Vannini have captured images of molecular machinery called RNA Polymerase III in the act of transcribing a gene in exquisite and unprecedented detail. Animation provided by Phospho Biomedical Animation more

White papers Cancer

• Designer Circular RNA as Protein Sponge for Cancer Therapy
  

  The new circular RNA enables specific binding and inhibition of heterogeneous nuclear ribonucleoprotein L in cells and thus opens new therapeutic more

• Weighing Cytostatics in Safety Weighing Cabinets
  

  Weighing Cytostatics in Safety Weighing Cabinets: a contract manufacturer of medications for individual patients, was looking for a balance that he could also use under laminar-flow conditions, which prevail in safety workbenches, safety weighing cab more

• Real-Time Assessment of Apoptosis and Necrosis
  

  Cell death is important for multicellular homeostasis but it also has an unfortunate role in human diseases more

Infographics Cancer

A Rough Guide to the IARC’s Carcinogen Classifications

Today’s big news has been the story that the World Health Organisation (WHO) has classified processed meat (including bacon, ham, and salami) as a Group 1 carcinogen. This places it in the same group as smoking, which has led to a number of headlines claiming that it means the risk from the two is t more

The Chemistry of Ginger

Ginger is a spice that can be commonly found in supermarkets and in the kitchen, either as the fresh root, or in dried, powdered form. It adds a strong, pungent flavour to dishes as a consequence of a number of chemical compounds it contains; additionally, these compounds are altered when the ginger more

Unleashing our immune systems against cancer

The first of the 2018 Nobel Prizes is awarded. The 2018 Nobel Prize in Physiology or Medicine was awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by stimulating the immune system to attack tumour cells. This graphic takes a look at the prize-winning research. more

Publications Cancer

• MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs [ARTICLE]

  MicroRNAs (miRNAs) are post-transcriptional gene regulators that play important roles in the control of cell fitness, differentiation, and development. The CRISPR-Cas9 gene-editing system is composed of the Cas9 nuclease in complex with a single guide RNA (sgRNA) and directs DNA cleavage at a prede more

• Computer aided detection and classification of Pap smear cell images using principal component analysis

  Computer aided detection and classification of Pap smear cell images using principal component analysisPonnusamy Sukumar; Samikannu RaviInternational Journal of Bio-Inspired Computation, Vol. 11, No. 4 (2018) pp. 257 - 266Pap smear is a screening methodology employed in cervix cancer detection and more

• Viruses, Vol. 10, Pages 352: HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

  Viruses, Vol. 10, Pages 352: HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses Viruses doi: 10.3390/v10070352 Authors: Laura Menotti Elisa Avitabile Valentina Gatta Paolo Malatesta Biljana Petrovic Gabriella Campadelli-Fiume more