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Filter membranes:

Sartocon® Hydrosart®

High‑Performance Tangential Flow Filtration Solutions for Biopharmaceutical Processing

Sartorius Stedim Biotech GmbH

Achieve superior separation performance with Hydrosart and polyethersulfone membrane technologies

Scale seamlessly from lab to production with filtration areas from 0.01 m² to 14 m²

Ensure contamination control: PES 0.1 μm MF achieves LRV ≥ 7 (static test conditions)

Scalable membrane technology for protein concentration, cell removal, and process purification

Tangential flow filtration (TFF) cassettes represent the industry standard for concentration, diafiltration, and cell separation. They combine proven membrane technologies with smart engineering to deliver consistent, high‑quality performance across diverse bioprocesses.

Comprehensive Membrane Portfolio

Hydrosart® offers ultra‑low protein adsorption and excellent cleanability, ideal for mAbs and other high‑value biologics. PES provides robust performance with broad operating compatibility for demanding processes.

Advanced Engineering Features

Self‑sealing cassettes eliminate gaskets and reduce potential contamination points. Enlarged ports help lower pressure drop and support economical, high‑flow operations. Silicone sealing delivers strong chemical compatibility and straightforward validation.

Flow Channel Geometry

E‑Screen supports higher protein concentrations and viscosities; ECO‑Screen is tuned for water‑based protein solutions at lower concentrations and viscosities.

Flexible Scale Integration

From Sartocon® Slice for development work to Sartocon® and Sartocube® for pilot and production scale, the portfolio enables predictable scale‑up. Hydrosart® ultrafiltration offers areas up to 14 m²; PES ultrafiltration up to 3.5 m².

Applications and Compliance

UF covers a wide range of biologics, including mAbs, vaccines, and advanced therapies; MF options address cell harvest and particle removal. All product contact materials meet relevant USP/EP requirements; each cassette is integrity‑tested and certified.

Single‑Use Options

Pre‑sterilized, ready‑to‑use self‑contained units support aseptic processing, reduce turnaround times, and simplify compliance by eliminating cleaning validation between batches.

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Filter membranes: Sartocon® Hydrosart®

High‑Performance Tangential Flow Filtration Solutions for Biopharmaceutical Processing