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TxCell achieves positive results for Col-Treg in a model of autoimmune uveitis

TxCell SA  announced that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options. TxCell demonstrated clear efficacy and tolerab ... more

Ventana announces collaboration to develop companion diagnostics for ImmunoGen's targeted anticancer agents

Ventana Medical Systems, Inc. announced it has entered into an agreement with ImmunoGen, Inc. to collaborate on the development of biomarker assays and a companion diagnostic immunohistochemistry (IHC) test for one or more of ImmunoGen's product candidates. Under this agreement, the compani ... more

QIAGEN announces broad agreement with Astellas Pharma to develop companion diagnostics

QIAGEN N.V.  announced a master collaboration agreement with Astellas Pharma Inc. to develop and commercialize companion diagnostics paired with Astellas drugs for use in cancer and other diseases. The scope of the agreement is not restricted to certain sample types, platforms, indications ... more

Figuring out how we get the nitrogen we need

Nitrogen is an essential component of all living systems, playing important roles in everything from proteins and nucleic acids to vitamins. It is the most abundant element in Earth's atmosphere and is literally all around us, but in its gaseous state, N2,, it is inert and useless to most o ... more

UF researchers discover leukemia’s hiding places

In patients with leukemia, cancer cells can embed within the walls of blood vessels and hide from chemotherapy, according to a University of Florida study published in Leukemia. Now, UF Health researchers are using a two-year, $800,000 grant from the Leukemia and Lymphoma Society to screen ... more

Synapses always on the starting blocks

While neurons rapidly propagate information in their interior via electrical signals, they communicate with each other at special contact points known as the synapses. Chemical messenger substances, the neurotransmitters, are stored in vesicles at the synapses. When a synapse becomes active ... more

Nabsys Appoints Anthony Shuber as Chief Scientific Officer

Nabsys, Inc. announced today Anthony Shuber has joined the company as Vice President and Chief Scientific Officer. In this role, Shuber will lead the company’s efforts in product strategy as the company transitions its initial commercial focus toward oncology. Shuber, an industry veteran an ... more

Novartis announces divestiture of influenza vaccines business to CSL for USD 275 million

Novartis announced it has entered into a definitive agreement to divest its influenza vaccines business to CSL Limited (CSL) for an agreed price of USD 275 million. This transaction requires regulatory approvals and is expected to close in the second half of 2015."In CSL, we have found not ... more

New engineering method shows promise for faster healing, more cosmetically appealing skin grafts

A new way to produce engineered skin not only appears to overcome several pitfalls of current skin grafting technologies, it also speeds up the healing process, reduces scarring and produces hair. The method, outlined in STEM CELLS Translational Medicine, could represent a breakthrough for ... more

Genmab Reaches USD 10 Million Milestone in Daratumumab Collaboration with Janssen

Genmab A/S announced it has reached the fourth milestone in its daratumumab collaboration with Janssen Biotech, Inc.. The USD 10 million milestone payment was triggered by progress in the ongoing Phase III study (“CASTOR” MMY3004) of daratumumab in combination with bortezomib and dexamethas ... more

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Nabsys Appoints Anthony Shuber as Chief Scientific Officer

Nabsys, Inc. announced today Anthony Shuber has joined the company as Vice President and Chief Scientific Officer. In this role, Shuber will lead the company’s efforts in product strategy as the company transitions its initial commercial focus toward oncology. Shuber, an industry veteran an ... more

New microscope collects dynamic images of the molecules that animate life

Over the last decade, powerful new microscopes have dramatically sharpened biologists' focus on the molecules that animate and propel life. Now, a new imaging platform developed by Eric Betzig and colleagues at the Howard Hughes Medical Institute's Janelia Research Campus offers another lea ... more

Eppendorf Award for Young European Investigators 2015: Call for entries

Until 15 January 2015, young researchers working in Europe who are not older than 35 years are invited to apply for the Eppendorf Award for Young European Investigators. This prize acknowledges outstanding contributions to biomedical research in Europe based on methods of molecular biology, ... more

Eurofins Genomics Extends Its Genomic Business Into Austria And Czech Republic

Eurofins Genomics, the genomics division of the Eurofins Scientific Group, has now established its own subsidiary in Austria. Customers will be served directly through Eurofins Genomics AT GmbH located in Vienna.The acquisition of the oligonucleotide synthesis and DNA sequencing businesses ... more

New sequencing reveals genetic history of tomatoes

An international team of researchers, led by the Chinese Academy of Agricultural Sciences in Beijing, published in the journal Nature Genetics a brief genomic history of tomato breeding, based on sequencing of 360 varieties of the tomato plant. The C.M. Rick Tomato Genetics Resource Center ... more

Eurofins Genomics Extends Its Genomic Business In Italy

Eurofins Genomics, the genomics division of the Eurofins Scientific Group, has now established its own subsidiary in Italy, located in Vimodrone, Milan. With the acquisition of the oligonucleotide synthesis and DNA sequencing business from Primm S.r.l. in June this year and the decision to ... more

Bibby Scientific Ltd acquires PCRmax Ltd

Bibby Scientific has purchased 100% of the share capital of PCRmax, a UK based sales and distribution Company set up specifically to capture a significant market share of the standard (PCR) and quantitative PCR (QPCR) markets. They are also the registered owners of the intellectual property ... more

Genetic Makeup of Europeans

The beginning of agriculture and animal domestication, which began in the Near East before 11,000 years ago, had a tremendous impact on human lifestyle. Hunter-gatherers were replaced in many places by sedentary farmers, and there were large increases in population size that laid the founda ... more

Gibbon genome sequenced

An international team of researchers that includes Christian Roos, Markus Brameier and Lutz Walter from the German Primate Center (DPZ) in Göttingen, have decoded the genome of gibbons from Southeast Asia. With this, the entire genetic information of five different species of this primate f ... more

Highly automated live cell imaging speeds up the search for new drugs

Fraunhofer FIT will present the latest version of its Zeta Fluorescence Image Analysis software at MipTec. Zeta, now extended to a software platform, supports the complete work process of finding new pharmaceutical agents. At MipTec, Fraunhofer FIT will demo advanced Zeta applications in ca ... more

All news on bioanalytics

TxCell achieves positive results for Col-Treg in a model of autoimmune uveitis

TxCell SA  announced that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options. TxCell demonstrated clear efficacy and tolerab ... more

Figuring out how we get the nitrogen we need

Nitrogen is an essential component of all living systems, playing important roles in everything from proteins and nucleic acids to vitamins. It is the most abundant element in Earth's atmosphere and is literally all around us, but in its gaseous state, N2,, it is inert and useless to most o ... more

UF researchers discover leukemia’s hiding places

In patients with leukemia, cancer cells can embed within the walls of blood vessels and hide from chemotherapy, according to a University of Florida study published in Leukemia. Now, UF Health researchers are using a two-year, $800,000 grant from the Leukemia and Lymphoma Society to screen ... more

Synapses always on the starting blocks

While neurons rapidly propagate information in their interior via electrical signals, they communicate with each other at special contact points known as the synapses. Chemical messenger substances, the neurotransmitters, are stored in vesicles at the synapses. When a synapse becomes active ... more

Scientists identify gene required for recovery from bacterial infection

When pathogenic bacteria like Salmonella or Staphylococcus invade a host, the host organism should respond by going into a state of high alert, altering its metabolism to defend against the attack. But if the host doesn't reverse course once the battle is won, its efforts will be wasted on ... more

Liftstream report finds ten men for every woman present in biotech boardrooms

Liftstream Ltd announces the publication of its new gender diversity report, “Diversifying the Outlook – The X&Y of Biotechnology Leadership”, a detailed analysis of women leaders in European and US life biotech companies. The research covers 700 companies, 60 C-level interviews and 530 sur ... more

Eppendorf Award for Young European Investigators 2015: Call for entries

Until 15 January 2015, young researchers working in Europe who are not older than 35 years are invited to apply for the Eppendorf Award for Young European Investigators. This prize acknowledges outstanding contributions to biomedical research in Europe based on methods of molecular biology, ... more

Pat Mackin Joins CryoLife Board of Directors

CryoLife, Inc. announced that James Patrick (Pat) Mackin, President and Chief Executive Officer, has been elected to the Company's Board of Directors, effective October 21, 2014.Mr. Mackin joined CryoLife in September 2014 from Medtronic, Inc., where he most recently served as President of ... more

Crown Bioscience Announces U.S. Expansion With New Translational Oncology Center

Crown Bioscience, Inc. has announced the opening of the Crown Bioscience US Research Center to be located at the David H. Murdock Research Institute (DHMRI), in Kannapolis, N.C. The new center, which will open in the 3rd quarter of 2014, represents significant U.S. market expansion for Crow ... more

Karus Therapeutics Appoints New Head of Clinical Development and Head of Biology

Karus Therapeutics announced that it has further strengthened its R&D team with two new appointments; Dr Simon Roitt, who joins as Head of Clinical Development and Dr Peter Finan, who has been appointed as Karus’s Head of Biology.Dr Roitt, who joined Karus in August, brings 20 years’ of cli ... more

All news on biotechnology

Ventana announces collaboration to develop companion diagnostics for ImmunoGen's targeted anticancer agents

Ventana Medical Systems, Inc. announced it has entered into an agreement with ImmunoGen, Inc. to collaborate on the development of biomarker assays and a companion diagnostic immunohistochemistry (IHC) test for one or more of ImmunoGen's product candidates. Under this agreement, the compani ... more

QIAGEN announces broad agreement with Astellas Pharma to develop companion diagnostics

QIAGEN N.V.  announced a master collaboration agreement with Astellas Pharma Inc. to develop and commercialize companion diagnostics paired with Astellas drugs for use in cancer and other diseases. The scope of the agreement is not restricted to certain sample types, platforms, indications ... more

Preventing Shock

Clinical shock is one of the most common causes of the high mortality rate among critically-ill patients in Intensive Care Units. During shock, the transport of oxygenated blood is not sufficient to meet the metabolic demands of the tissue. Early detection is important as shock-preventing m ... more

Earlier unknown molecular-level mechanism may contribute to the growth rate of breast cancer

Researchers at VTT Technical Research Centre of Finland, the University of Turku and the University of Oslo have discovered a previously unknown molecular-level mechanism that may partly explain the increased growth of cancer cells. The study, published in the British Journal of Cancer, sho ... more

New clues for the early detection of colorectal cancer

Researchers at the University of Luxembourg have identified potential new ways to test for the first signs of one of the most deadly types of cancer: colorectal cancer. They have found new “biomarkers”: molecules whose increased presence or absence in tissue suggests the development of tumo ... more

New blood test determines whether you have or are likely to get cancer

A new research report published in the October 2014 issue of The FASEB Journal may make the early detection of cancer as easy as a simple blood test. This test, called the "lymphocyte genome sensitivity" (LGS) test, could not only detect some cancers earlier than ever before, but it may eli ... more

'Virtual breast' could improve cancer detection

Next to lung cancer, breast cancer is the leading cause of cancer death in women, according to the American Cancer Society. That's why so many medical professionals encourage women to get mammograms, even though the tests are imperfect at best: only a minority of suspicious mammograms actua ... more

analytica China 2014: Closed with overall success

On September 26 analytica China 2014 closed with record-breaking visitor numbers: 18,775 business professionals (2012: 16,940) from 62 countries attended the seventh edition of Chinas Leading Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics at the Shanghai New I ... more

Innovative image sensing technology for early diagnosis of diabetes and Alzheimer’s disease

Professor Kazuaki Sawada and Dr. Takigawa of the National Center for Geriatrics and Gerontology and colleagues at Toyohashi University of Technology have established an easy to use, low-cost, rapid, and high sensitivity semiconductor-imaging based medical diagnostic biosensing system for an ... more

Mechanism of Parkinson's spread demonstrated

An international, interdisciplinary group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has demonstrated, through the use of a new antibody, how Parkinson's disease spreads from cell to cell in the human brain.Until now, this mechanism h ... more

All news on diagnostics

analytica China 2014: Closed with overall success

On September 26 analytica China 2014 closed with record-breaking visitor numbers: 18,775 business professionals (2012: 16,940) from 62 countries attended the seventh edition of Chinas Leading Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics at the Shanghai New I ... more

Messe München International takes over one of India's leading trade fairs for laboratory technology

Messe München International is strengthening its portfolio of events in the future market of India by taking over India Lab Expo, one of the leading trade fairs for laboratory technology, analysis and biotechnology on the Indian subcontinent. For the first time ever, this year's India Lab E ... more

Bochem Increasingly Using New Media

Bochem Instrumente GmbH presents sections of its overall product spectrum in various new videos. The recently finished productions provide a compact overview of the product groups of lab jacks, electrical lifts, containers as well as stands and clamps. They can be found on the company’s web ... more

Merger of CyBio AG into Analytik Jena AG Completed

The merger of CyBio AG into Analytik Jena AG became effective upon entry into the commercial register of Analytik Jena AG (commercial register of the Registry Court of Jena, HRB 200027). As a result, CyBio AG is dissolved as an independent company. In the future, the Life Science business u ... more

LABVOLUTION – the new lab technology show in Hannover

Deutsche Messe is launching LABVOLUTION, a new trade fair to be staged every two years as amajor platform for the world of lab technology and equipment. LABVOLUTIONmakes its debut from 6 to 8 October 2015 at the Hannover Exhibition Center in Hannover, Germany, where it will take place every ... more

Automating Laboratory-On-A-Chip To Cut Healthcare Costs

A research team at the University of California, Riverside has created a computer programming language that will automate “laboratory-on-a-chip” technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.“If you think of the beginning of computers ... more

Reorganization of the Executive Board of Eppendorf AG

The Executive Board of Eppendorf AG is reshaping in order to be optimally equipped to meet the future demands of the market. Dr. Dirk Ehlers, Chairman of the Executive Board of the Eppendorf Group, will leave the company by mutual agreement. Detmar Ammermann (Chief Financial Officer) will r ... more

New microscope sees what others can't

Microscopes don't exactly lie, but their limitations affect the truths they can tell. For example, scanning electron microscopes (SEMs) simply can't see materials that don't conduct electricity very well, and their high energies can actually damage some types of samples. In an effort to ext ... more

A lab in your pocket

When you get sick, your physician may take a sample of your blood, send it to the lab and wait for results. In the near future, however, doctors may be able to run those tests almost instantly on a piece of plastic about the size of credit card. These labs-on-a-chip would not only be quick— ... more

Sartorius with Gains

Sartorius got off to a good start in fiscal 2014, with gains in order intake and sales revenue. In constant currencies, Group sales revenue rose 6.3% and order intake increased 4.9%. Despite negative currency impacts, operating Profit for the Group also grew 2.0%; its respective margin afte ... more

All news on lab technology

TxCell achieves positive results for Col-Treg in a model of autoimmune uveitis

TxCell SA  announced that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options. TxCell demonstrated clear efficacy and tolerab ... more

UF researchers discover leukemia’s hiding places

In patients with leukemia, cancer cells can embed within the walls of blood vessels and hide from chemotherapy, according to a University of Florida study published in Leukemia. Now, UF Health researchers are using a two-year, $800,000 grant from the Leukemia and Lymphoma Society to screen ... more

Novartis announces divestiture of influenza vaccines business to CSL for USD 275 million

Novartis announced it has entered into a definitive agreement to divest its influenza vaccines business to CSL Limited (CSL) for an agreed price of USD 275 million. This transaction requires regulatory approvals and is expected to close in the second half of 2015."In CSL, we have found not ... more

Genmab Reaches USD 10 Million Milestone in Daratumumab Collaboration with Janssen

Genmab A/S announced it has reached the fourth milestone in its daratumumab collaboration with Janssen Biotech, Inc.. The USD 10 million milestone payment was triggered by progress in the ongoing Phase III study (“CASTOR” MMY3004) of daratumumab in combination with bortezomib and dexamethas ... more

Clinuvel drug approved in Europe for rare sun disorder

Clinuvel Pharmaceuticals Ltd has announced that its drug SCENESSE® (afamelanotide 16mg) has received its first approval from the European Medicines Agency (EMA) to treat a disease caused by exposure to sunlight. The EMA’s Committee for Medicinal Products for Human Use (CHMP) voted in favour ... more

Siegfried facility in Nantong receives operating approval

Siegfried received operating approval for Phase I of the production plant for active pharmaceutical ingredients at its new facility in Nantong, near Shanghai, China. Validation of the new plant commences with production in the pilot plant. Siegfried plans to produce first commercial batches ... more

Cardio3 BioSciences appoints Dr. Warren Sherman as Chief Medical Officer

Cardio3 BioSciences (C3BS)  announced the appointment of Dr. Warren Sherman as Chief Medical Officer, effective as of 1 November 2014. In this new role, Dr. Sherman will leverage his deep expertise in the cardiovascular and cell therapy fields to support the continued development of Cardio3 ... more

TSRI chemists achieve new technique with profound implications for drug development

Breaking carbon-hydrogen (C-H) bonds to alter existing molecules to create new ones is an increasingly important avenue for drug development. Of particular interest is mirror-image or "one-handed" compounds, but C-H breaking methods for making pure batches of these molecules have worked wit ... more

ERYTECH announces granting of new patent in the United States

ERYTECH reports positive Phase III results from its pivotal study with GRASPA(R) in Acute Lymphoblastic Leukemia.Analysis of the primary and first secondary efficacy endpoints of the GRASPALL clinical trial with one year follow up shows that the GRASPIVOTALL (GRASPALL2009-06) clinical trial ... more

Aesica appoints VP, Business Development and Business Development Director for Finished Dose

Aesica announced the appointment of two senior business development positions. Detlef Behrens has been appointed to the role of Vice President, Business Development, Finished Dose with Sven Wrabletz joining as Business Development Director, Finished Dose. Detlef has overall responsibility f ... more

All news on pharma

UF researchers discover leukemia’s hiding places

In patients with leukemia, cancer cells can embed within the walls of blood vessels and hide from chemotherapy, according to a University of Florida study published in Leukemia. Now, UF Health researchers are using a two-year, $800,000 grant from the Leukemia and Lymphoma Society to screen ... more

New engineering method shows promise for faster healing, more cosmetically appealing skin grafts

A new way to produce engineered skin not only appears to overcome several pitfalls of current skin grafting technologies, it also speeds up the healing process, reduces scarring and produces hair. The method, outlined in STEM CELLS Translational Medicine, could represent a breakthrough for ... more

Scientists identify gene required for recovery from bacterial infection

When pathogenic bacteria like Salmonella or Staphylococcus invade a host, the host organism should respond by going into a state of high alert, altering its metabolism to defend against the attack. But if the host doesn't reverse course once the battle is won, its efforts will be wasted on ... more

Flu viruses disguised as waste

Viral infections always follow a similar course. The pathogen infiltrates the host cells and uses their replication and protein production machinery to multiply. The virus has to overcome the initial barrier by docking on the surface of the cell membrane. The cell engulfs the virus in a bub ... more

Earlier unknown molecular-level mechanism may contribute to the growth rate of breast cancer

Researchers at VTT Technical Research Centre of Finland, the University of Turku and the University of Oslo have discovered a previously unknown molecular-level mechanism that may partly explain the increased growth of cancer cells. The study, published in the British Journal of Cancer, sho ... more

Adenosine can melt "love handles"

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer's disease. For this reason, many people dream of an efficient method for losing weight. An international team of researchers led by Profe ... more

Sugared soda consumption, cell aging associated in new study

Sugar-sweetened soda consumption might promote disease independently from its role in obesity, according to UC San Francisco researchers who found in a new study that drinking sugary drinks was associated with cell aging. The study revealed that telomeres — the protective units of DNA that ... more

Immune cells in the liver drive fatty liver disease and liver cancer

Immune cells that migrate to the liver and interact there with liver tissue cells get activated by metabolic stress (e.g. through lipids of a high fat diet) and drive the development of fatty liver disease, non-alcoholic steatohepatitis and liver cancer. Scientists from the Helmholtz Zentru ... more

Study reveals optimal particle size for anticancer nanomedicines

Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy. Understanding the interdependency of physiochemical properties of nanomedicines, in correlation to their biological responses and function ... more

Effects of high-risk Parkinson's mutation are reversible

Researchers from the University of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson's. Mutations in a gene called LRRK2 carry a well-established risk for Parkinson's disease, however the basis for t ... more

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