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Chemical cages: New technique advances synthetic biology

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes. In a new study, Hao Yan, director of the Center for Molecular Design and Biomimetics at Arizona State Universit ... more

X-ray laser turns crystal imperfections into better images of important biomolecules

Often the most difficult step in taking atomic-resolution images of biological molecules is getting them to form high-quality crystals needed for X-ray studies of their structure. Now researchers have shown they can get sharp images even with imperfect crystals using the world's brightest X ... more

Penn researchers offer new approach to treating cocaine addiction

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine depend ... more

Estrogen, antibiotics persisted in dairy farm waste after advanced treatment

When University at Buffalo chemists began studying waste disposal at a dairy farm in New York State, they thought that the farm's advanced system for processing manure would help remove estrogens and antibiotics from the excrement. Instead, the scientists found that the chemicals largely pe ... more

INNUENDO -- a new platform for genomics integration in surveillance of food-borne pathogens

Multinational outbreaks of food-borne pathogens cause considerable threats to European public health. Implementing a whole genome sequencing (WGS) in routine surveillance and outbreak investigations is becoming a strategic goal for many public health authorities all over the world. With thi ... more

Almirall closes the acquisition of ThermiGen LLC

Almirall, S.A. announced the completion of the acquisition of 100% of the share capital of ThermiGen LLC, after all closing conditions have been satisfied. In accordance with the terms of the agreement signed in September 2015, the transaction has been fulfilled and Almirall now owns this m ... more

Sanofi delivered 2015 business EPS up 8.5%

Sales growth in Pharmaceuticals, Vaccines and Animal Health in 2015 The aggregate Group sales went up 2.2% (+9.7% at 2015 exchange rates) to €37,057 million with Genzyme continuing to be a key driver with sales up 29.5% with strong momentum in multiple sclerosis. Sales of vaccines were up 7 ... more

UCB and Baylor College of Medicine launch strategic alliance in neurodegeneration

UCB and Baylor College of Medicine announced that they have started a strategic research alliance, led at Baylor by Professor Huda Zoghbi, that aims to discover new therapeutics to treat neurodegenerative disease. This research alliance reflects UCB’s strategy to accelerate discovery and de ... more

Penn researchers illuminate 'dark side' of the transcriptome

A new way of mapping the "transcriptome" - the collection of RNA read-outs that are expressed by a cell's active genes - has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania. RNA is both the molecular bridge between DNA and the production of ... more

Engineering researchers use laser to 'weld' neurons

A research team based in the University of Alberta Faculty of Engineering has developed a method of connecting neurons, using ultrashort laser pulses--a breakthrough technique that opens the door to new medical research and treatment opportunities. The team is the first ever to find a way t ... more

All news

X-ray laser turns crystal imperfections into better images of important biomolecules

Often the most difficult step in taking atomic-resolution images of biological molecules is getting them to form high-quality crystals needed for X-ray studies of their structure. Now researchers have shown they can get sharp images even with imperfect crystals using the world's brightest X ... more

More detailed analysis of how cells react to stress

Stress in the body’s cells is both the cause and consequence of inflammatory diseases or cancer. The cells react to stress to protect themselves. Researchers at the University of Zurich have now developed a new technique that allows studying a fundamental response to stress in much more det ... more

Molecular switch lets salmonella fight or evade immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm. Biofilms cling to surfaces in the body, such as the bronchial t ... more

New insights into the function of the main class of drug targets

About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. In collaboration with researchers from the Paul Scherrer Institute, the group of Prof. Stephan Grzesiek at the Biozentr ... more

Biomolecule’s behaviour under artificial conditions more natural than expected

Researchers often analyse isolated biomolecules in test tubes, and it is doubtful if the results can be applied to densely-packed cells. A team from Bochum, Dortmund and Greifswald monitored the folding of an RNA structure in the living cell and compared the results with those of test tube ... more

'Gene fusion' mutation uses 3-way mechanism to drive childhood brain cancers

A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP). The team hopes the discovery will lead to ... more

Suitable Protein Tags for Nanoscopy

Modern optical technologies such as super-resolution nanoscopy enable to exactly image small structures and molecular processes, therefore, providing a fascinating view into living cells. To visualize such processes in the nanometer range, cellular structures of interest have to be efficien ... more

The device with the fine nose

When it comes to measuring the smallest traces of volatile chemical compounds in the air, the analysis devices in Pablo Sinues' laboratory are among the most sensitive in the world. They can find the proverbial needle in a haystack: the detection limit for airborne volatile compounds is aro ... more

Sweating for science

A team of researchers has combined two separate technologies to create a health-monitoring device that is noninvasive, doesn't interfere with strenuous outdoor activities and can continuously track a user's health at the molecular level. The two-part system of flexible sensors and a flexibl ... more

Drugs and other contaminants found in private drinking wells on Cape Cod

Recent news about tainted water in Flint, Michigan, and other parts of the country have called into question the safety of the nation's drinking water supply. Adding to this, a new study finds that pollutants from household wastewater--pharmaceuticals and consumer product chemicals--can mak ... more

All news on bioanalytics

Chemical cages: New technique advances synthetic biology

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes. In a new study, Hao Yan, director of the Center for Molecular Design and Biomimetics at Arizona State Universit ... more

Body temperature triggers newly developed polymer to change shape

Polymers that visibly change shape when exposed to temperature changes are nothing new. But a research team led by Chemical Engineering Professor Mitch Anthamatten at the University of Rochester created a material that undergoes a shape change that can be triggered by body heat alone, openi ... more

From allergens to anodes: pollen derived battery electrodes

Pollens, the bane of allergy sufferers, could represent a boon for battery makers: Recent research has suggested their potential use as anodes in lithium-ion batteries. "Our findings have demonstrated that renewable pollens could produce carbon architectures for anode applications in energy ... more

Uncovering the secrets of elastin’s flexibility

Elastin is a crucial building block in our bodies - its flexibility allows skin to stretch and twist, blood vessels to expand and relax with every heartbeat, and lungs to swell and contract with each breath. But exactly how this protein-based tissue achieves this flexibility remained an uns ... more

Proteomics and precision medicine

As medical professionals search for new ways to personalize diagnosis and treatment of disease, a research team at the University of Iowa has already put into practice what may be the next big step in precision medicine: personalized proteomics. Proteomics is the large-scale analysis of all ... more

Key step toward custom-made nanoscale chemical factories

Scientists have for the first time reengineered a building block of a geometric nanocompartment that occurs naturally in bacteria. They introduced a metal binding site to its shell that will allow electrons to be transferred to and from the compartment. This provides an entirely new functio ... more

Scientists guide gold nanoparticles to form 'diamond' superlattices

Using bundled strands of DNA to build Tinkertoy-like tetrahedral cages, scientists at the U.S. Department of Energy's Brookhaven National Laboratory have devised a way to trap and arrange nanoparticles in a way that mimics the crystalline structure of diamond. The achievement of this comple ... more

New scaffold-free 3-D bioprinting available

Cell Applications, Inc. and Cyfuse Biomedical K.K. have announced that advanced tissue-engineering services are now available in North America using a groundbreaking new three-dimensional (3D) bioprinting approach called the "Kenzan Method." Utilizing Cyfuse Biomedical's Regenova® 3D Bio Pr ... more

Hepatitis virus-like particles as potential cancer treatment

UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research. Hepatit ... more

Sartorius Grows by Double Digits

Sartorius grew very dynamically again in 2015 according to its preliminary figures and further increased its profitability. The company achieved or exceeded its financial targets raised during the reporting year. For the current fiscal year as well, management expects to record significant ... more

All news on biotechnology

'Gene fusion' mutation uses 3-way mechanism to drive childhood brain cancers

A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP). The team hopes the discovery will lead to ... more

Suitable Protein Tags for Nanoscopy

Modern optical technologies such as super-resolution nanoscopy enable to exactly image small structures and molecular processes, therefore, providing a fascinating view into living cells. To visualize such processes in the nanometer range, cellular structures of interest have to be efficien ... more

New biomarker to assess stem cells developed

A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). The team's discovery offers a new way to fast-track screening methods used in stem cell research. iPSCs are derived from cells, u ... more

PerkinElmer acquires Vanadis Diagnostics

PerkinElmer, Inc., announced that it has completed the acquisition of Vanadis Diagnostics, AB. Based in Sweden, Vanadis is developing a novel solution for non-invasive prenatal testing (NIPT) based on digital analysis of cell-free DNA. The acquisition is anticipated to build upon PerkinElme ... more

1 in 7 colorectal cancer patients diagnosed before recommended screening age

Nearly 15 percent of patients diagnosed with colorectal cancer were younger than 50, the age at which screening recommendations begin. The study by researchers at the University of Michigan Comprehensive Cancer Center also found that younger patients were more likely to have advanced diseas ... more

Will blocking IL-17A help treat kidney disease?

Many different diseases and insults can injure kidneys, resulting in kidney failure. Some autoimmune diseases damage glomeruli (the 'filtering units' of the kidney), while problems with the tubules (for example, impaired blood flow to the kidney at the time of renal transplantation, radio-c ... more

Researchers pinpoint place where cancer cells may begin

Cancer cells are normal cells that go awry by making bad developmental decisions during their lives. In a study involving the fruit fly equivalent of an oncogene implicated in many human leukemias, Northwestern University researchers have gained insight into how developing cells normally sw ... more

To hear a pitter patter from afar

Heartbeats can now be measured without placing sensors on the body, thanks to a new technology developed in Japan. Researchers at the Kyoto University Center of Innovation, together with Panasonic Corp, have come up with a way to measure heartbeats remotely, in real time, and under controll ... more

Agilent Technologies extends agreement with PerkinElmer on bioanalyzer chips

Agilent Technologies Inc.announced an extension to its longstanding agreement with PerkinElmer, which supplies chips for Agilent’s popular 2100 Bioanalyzer system. Since its introduction in 1999, the 2100 Bioanalyzer system has become an integral part of molecular biology laboratories aroun ... more

Research finds possible answer to why some develop Alzheimer’s - and others don’t

Alzheimer’s disease affects millions, but there is no cure and no real test for the diagnosis until death, when an examination of the brain can reveal the amyloid plaques that are a telltale characteristic of the disease. Interestingly, the same plaque deposits have also been found in the b ... more

All news on diagnostics

Sartorius Grows by Double Digits

Sartorius grew very dynamically again in 2015 according to its preliminary figures and further increased its profitability. The company achieved or exceeded its financial targets raised during the reporting year. For the current fiscal year as well, management expects to record significant ... more

The device with the fine nose

When it comes to measuring the smallest traces of volatile chemical compounds in the air, the analysis devices in Pablo Sinues' laboratory are among the most sensitive in the world. They can find the proverbial needle in a haystack: the detection limit for airborne volatile compounds is aro ... more

New nanomanufacturing technique advances imaging, biosensing technology

More than a decade ago, theorists predicted the possibility of a nanolens--a chain of three nanoscale spheres that would focus incoming light into a spot much smaller than possible with conventional microscopy. Such a device would make possible extremely high-resolution imaging or biologica ... more

BioFluidix wins STEP award

Increasing the speed, safety and cost efficiency of sample analysis: BioFluidix wins the process-category price at the 2015 STEP Award with its PipeJet Tip pipetting technology. Once per year, Infraserv Höchst KG and the F.A.Z. – Institute honor innovative and strongly growing companies of ... more

Analytik Jena Opens Swiss Branch Office at the Endress+Hauser Headquarters

Analytik Jena AG has established a branch office on the premises of Endress+Hauser at the Reinach site near Basel in Switzerland. “This step is part of our strategy to further expand our international sales structure and to establish our own organization and direct sales wherever tangible g ... more

Sartorius grows

Sartorius closed the first nine months of 2015 with significant double-digit gains in order intake, sales revenue and earnings. Group order intake rose 19.9%, excluding currency effects, to 856.6 million euros; the reported figure surged 30.2%. Its sales revenue climbed 18.5% in constant cu ... more

Successful launch of BIOTECHNICA and LABVOLUTION

The producers of the BIOTECHNICA and LABVOLUTION dual exhibition drew positive conclusions at the close of the event. Some 10,000 trade visitors traveled to Hannover to take advantage of the business opportunities offered by BIOTECHNICA as the European networking hub for bio¬technology and ... more

Analytik Jena AG Expands Executive Management Board

At a meeting in September, the Supervisory Board of Analytik Jena AG made the decision to expand the Company’s Executive Board. In this way, the Company is responding to its growth and the ever-increasing challenges associated with its operational business. The management body of the Jena-b ... more

New smart robot accelerates cancer treatment research

A new smart research robot accelerates research on cancer treatments. The new robot system finds optimal treatment combinations. Today complex diseases like cancer is medically almost exclusively treated by combining several different drugs. These combinations are typically composed from dr ... more

Eppendorf supports the smartLAB project

Eppendorf AG will be presenting the incorporation of its laboratory devices and consumables into digitalized work processes at the smartLab stand. The advantages of topics such as documentation, process monitoring and automation of repeatedly performed tasks in the laboratory are illustrate ... more

All news on lab technology

Almirall closes the acquisition of ThermiGen LLC

Almirall, S.A. announced the completion of the acquisition of 100% of the share capital of ThermiGen LLC, after all closing conditions have been satisfied. In accordance with the terms of the agreement signed in September 2015, the transaction has been fulfilled and Almirall now owns this m ... more

Sanofi delivered 2015 business EPS up 8.5%

Sales growth in Pharmaceuticals, Vaccines and Animal Health in 2015 The aggregate Group sales went up 2.2% (+9.7% at 2015 exchange rates) to €37,057 million with Genzyme continuing to be a key driver with sales up 29.5% with strong momentum in multiple sclerosis. Sales of vaccines were up 7 ... more

UCB and Baylor College of Medicine launch strategic alliance in neurodegeneration

UCB and Baylor College of Medicine announced that they have started a strategic research alliance, led at Baylor by Professor Huda Zoghbi, that aims to discover new therapeutics to treat neurodegenerative disease. This research alliance reflects UCB’s strategy to accelerate discovery and de ... more

Some heart drugs and antibiotics show effective in fighting cancer

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research. These drugs are normally used to treat other diseases, such as heart failure, cardiac arrhythmia, and infections. "We identified ... more

New insights into the function of the main class of drug targets

About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. In collaboration with researchers from the Paul Scherrer Institute, the group of Prof. Stephan Grzesiek at the Biozentr ... more

Hepatitis virus-like particles as potential cancer treatment

UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research. Hepatit ... more

Sartorius Grows by Double Digits

Sartorius grew very dynamically again in 2015 according to its preliminary figures and further increased its profitability. The company achieved or exceeded its financial targets raised during the reporting year. For the current fiscal year as well, management expects to record significant ... more

New research uses nanotechnology to prevent preterm birth

Using nanoparticles to engineer a special drug, a team of researchers has demonstrated in mice a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies. Jerrie S. Refuerzo, M.D., of the University of Texas Medical School at Houston (UTHealth) wa ... more

Drug that could aid in vaccines activates innate immune system in novel way

A new drug with the potential to aid in vaccine development has been identified by researchers at UT Southwestern Medical Center. "The drug we made appears safe, and boosts immunity in mice. Therefore, the drug, which is straightforward to synthesize and to couple to antigens that induce an ... more

Seaweed offers the solution to transporting stem cells and wound treatment

Che Connon, Professor of Tissue Engineering at Newcastle University explains: "The stem cells are surrounded by an alginate gel which protects them from the environment -- a bit like frogspawn. We found them unchanged even after three days at room temperature. "This has lots of advantages a ... more

All news on pharma

Penn researchers offer new approach to treating cocaine addiction

In the ongoing fight against drug addiction, researchers from the University of Pennsylvania's School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine depend ... more

Penn researchers illuminate 'dark side' of the transcriptome

A new way of mapping the "transcriptome" - the collection of RNA read-outs that are expressed by a cell's active genes - has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania. RNA is both the molecular bridge between DNA and the production of ... more

Engineering researchers use laser to 'weld' neurons

A research team based in the University of Alberta Faculty of Engineering has developed a method of connecting neurons, using ultrashort laser pulses--a breakthrough technique that opens the door to new medical research and treatment opportunities. The team is the first ever to find a way t ... more

Some heart drugs and antibiotics show effective in fighting cancer

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research. These drugs are normally used to treat other diseases, such as heart failure, cardiac arrhythmia, and infections. "We identified ... more

Proteomics and precision medicine

As medical professionals search for new ways to personalize diagnosis and treatment of disease, a research team at the University of Iowa has already put into practice what may be the next big step in precision medicine: personalized proteomics. Proteomics is the large-scale analysis of all ... more

Mesh-like scaffold is disordered in Alzheimer's-affected cells

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said. The finding is expected to open new avenues of study of how to ... more

Molecular switch lets salmonella fight or evade immune system

Researchers at the University of Illinois at Chicago have discovered a molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm. Biofilms cling to surfaces in the body, such as the bronchial t ... more

New scaffold-free 3-D bioprinting available

Cell Applications, Inc. and Cyfuse Biomedical K.K. have announced that advanced tissue-engineering services are now available in North America using a groundbreaking new three-dimensional (3D) bioprinting approach called the "Kenzan Method." Utilizing Cyfuse Biomedical's Regenova® 3D Bio Pr ... more

Nutrient deprivation kills kidney cancer cells

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread. For decades, scientists have been trying to exploit this greedy metabolism as a target f ... more

Hepatitis virus-like particles as potential cancer treatment

UC Davis researchers have developed a way to use the empty shell of a Hepatitis E virus to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is available for commercial licensing through UC Davis Office of Research. Hepatit ... more

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