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Merck expands distribution agreement with Roche

Merck announced an expansion of its distribution alliance with Roche to include the polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products of Kapa Biosystems, a company acquired by Roche in 2015. The addition of the Kapa portfolio strengthens Merck’s existing ... more

New strategy may drop cancer's guard

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists. Rice bioscientist Daniel Carson and alumna Micaela Morgado re ... more

Drug delivery modification sidesteps allergic responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also ... more

Watson-Marlow Fluid Technology Group acquires Aflex Hose Ltd

Watson-Marlow Fluid Technology Group has acquired Aflex Hose Limited and its subsidiary Aflex Hose USA LLC (Aflex) through its parent company Spirax-Sarco Engineering plc, for £61.4 million. Aflex, based in Halifax, England and with a sales/assembly operation in Pennsylvania, USA, specializ ... more

Danaher announces leadership appointment

Danaher Corporation announced that effective January 1, 2017, Rainer Blair has been promoted to Executive Vice President of Danaher Corporation, with responsibility for the Company's $5 billion Life Sciences platform. Mr. Blair, 52 years old, has served in a series of progressively more res ... more

Psilocybin eases existential anxiety in people with life-threatening cancer

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushroom ... more

New insights into skin cells could explain why our skin doesn't leak

The discovery of the shape and binding capability of epidermal cells could explain how skin maintains a barrier even when it is shedding. The authors of the study say their new understanding of how epidermal cells form a barrier may explain the paradox of how we can shed them without compro ... more

Potential new tool to aid breast cancer surgery

University of Adelaide researchers have developed an s that distinguishes breast cancer tissue from normal tissue - potentially allowing surgeons to be much more precise when removing breast cancer. The device could help prevent follow-up surgery, currently needed for 15-20% of breast cance ... more

Takeda to invest more than 100 million Euros in dengue vaccine manufacturing plant

Takeda Pharmaceutical Company Limited announced that it will invest more than 100 Million Euros to build a new manufacturing plant for its dengue vaccine candidate in Singen, Germany. This represents a major step by Takeda toward meeting important unmet needs in dengue prevention. According ... more

Peptides as tags in fluorescence microscopy

Advance in biomedical imaging

The Biocenter of the University of Würzburg in close collaboration with the University of Copenhagen has developed an alternative approach to fluorescent tagging of proteins. The new probes are practicable and compatible with high-resolution microscopic procedures. Fluorescence microscopy ... more

All news

Peptides as tags in fluorescence microscopy

Advance in biomedical imaging

The Biocenter of the University of Würzburg in close collaboration with the University of Copenhagen has developed an alternative approach to fluorescent tagging of proteins. The new probes are practicable and compatible with high-resolution microscopic procedures. Fluorescence microscopy ... more

Mysteries of enzyme mechanism revealed

An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its structure using a beam of neutrons from the heart of a nuclear reactor. The Leicester team me ... more

Staph uses nitric oxide enzyme to colonize noses

Staph bacteria colonize nasal passages through a newly discovered function for a primeval biochemical mechanism. The interior of the nose is a prime dwelling place for some forms of staph. More than one-third of the population has a chronic presence of Staphylococcus aureus in their nostril ... more

Enough is enough

Stem cell factor Nanog knows when to slow down

The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. Previously unclear was how its protein abundance is regulated in the cells. Researchers at the Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with col ... more

Breaking new territory analyzing DNA modifications in glioblastoma

Using state-of-the-art molecular biology and statistical approaches, researchers at Dartmouth's Norris Cotton Cancer Center (NCCC) have identified the functional role of two distinct DNA modifications in glioblastoma (GBM) tissues. The signature of one of these pattern disruptions in partic ... more

Tosoh to Increase Production Capacity of Liquid Chromatography Separation and Purification Media

Tosoh Corporation has announced that it will be increasing the production capacity of its Toyopearl liquid chromatography separation and purification media at its Nanyo Complex, in Shunan, Yamaguchi Prefecture. The nearly 50% production capacity increase is in response to growing global dem ... more

Missed Connections

Studies of brain activity typically draw their findings from measurement averages across entire groups of subjects. But new research out of UC Santa Barbara that highlights a novel method of characterizing and comparing the brain dynamics in individuals may signal a shift in that approach. ... more

Multi-organ platform for risk assessment of nanomaterials

Multimodular microchip platform for predicting the behaviour of nanomaterials in the body

Nanomaterials are already part of everyday life in our modern society. New applications, along with continuously rising quantities being produced, have led to an increased exposure to nanomaterials for both people and the environment. Predicting the behaviour of nanomaterials in organisms a ... more

The birth of the brightest red glowing protein

The brightest red fluorescent protein ever, mScarlet, has just been engineered by researchers at the University of Amsterdam, the Institut de Biologie Structurale, IBS (CEA/CNRS/University Grenoble Alpes) and the European Synchrotron (ESRF) in France. mScarlet can be used to monitor the act ... more

Cancer cells 'talk' to their environment, and it talks back

Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood is the mechanical force that governs those interactions. A multidisciplinary team of Cornell ... more

All news on bioanalytics

Danaher announces leadership appointment

Danaher Corporation announced that effective January 1, 2017, Rainer Blair has been promoted to Executive Vice President of Danaher Corporation, with responsibility for the Company's $5 billion Life Sciences platform. Mr. Blair, 52 years old, has served in a series of progressively more res ... more

Creation of micro muscles aids better understanding of muscle efficiency

A biomedical research scientist is taking the lead in the creation of muscle cells and micro muscles to test muscle efficiency in the laboratory - and he is able to carry out this new and innovative work thanks to the support he has received to get him back into science after a career break ... more

Breaking new territory analyzing DNA modifications in glioblastoma

Using state-of-the-art molecular biology and statistical approaches, researchers at Dartmouth's Norris Cotton Cancer Center (NCCC) have identified the functional role of two distinct DNA modifications in glioblastoma (GBM) tissues. The signature of one of these pattern disruptions in partic ... more

analytica 2018: Preparations for the upcoming exhibition are underway

Exhibitors can now register for analytica 2018. As the leading international trade fair for the analysis, laboratory technology and biotechnology industry, analytica has been a gathering for decision-makers and users in the laboratory community for 50 years. The next edition of analytica ta ... more

Bringing silicon to life

Scientists persuade nature to make silicon-carbon bonds

A new study is the first to show that living organisms can be persuaded to make silicon-carbon bonds--something only chemists had done before. Scientists at Caltech "bred" a bacterial protein to make the man-made bonds--a finding that has applications in several industries. Molecules with s ... more

First-ever Buyer-Seller Forum at analytica Vietnam

Having the right contacts and a good network are indispensible in the business world. To help exhibitors and visitors make business contacts that suit them to a tee, for the first time ever analytica 2017 will feature a platform for pre-arranged meetings at a Buyer-Seller Forum. The Buyer-S ... more

With a little help from my fungus

Fungus increases resistance of tomato plants against worms

Plants are constantly challenged by hungry animals and infectious microbes. Tomato plants, for example, are often infested with little worms that feed on their roots. A fungus can help them to better defend themselves against these attacks. In the future, farmers and gardeners might benefit ... more

Targeting the “un-targetable”

Targeting the protein RSK blocked aggressive breast cancers from metastasizing in an animal model.

Triple negative breast cancers (TNBC) are so named because they lack common genetic “target” mutations that can be easily treated with specific cancer drugs. However Deborah Lannigan , Ph.D., and colleagues investigated a new target involved in TNBC called RSK. They demonstrated that RSK ca ... more

Updating embryo research guidelines

With advancing lab technology perhaps calling into question a longstanding guideline that prohibits experimentation on human embryos older than 14 days, scientists and ethicists gathered at Harvard Law School recently to discuss whether and how that stricture should be revised. Some speaker ... more

New class of drugs holds promise for combating antibiotic resistance

A new class of drugs that combat antibiotic resistance has been discovered by a University of Oklahoma researcher and team. In the study supported by the National Institutes of Health, laboratory experiments were combined with supercomputing modeling to identify molecules that boost the eff ... more

All news on biotechnology

Potential new tool to aid breast cancer surgery

University of Adelaide researchers have developed an s that distinguishes breast cancer tissue from normal tissue - potentially allowing surgeons to be much more precise when removing breast cancer. The device could help prevent follow-up surgery, currently needed for 15-20% of breast cance ... more

ZEISS and EPFL begin long-term research collaboration

ZEISS will support innovative research projects at the Swiss Federal Institute of Technology in Lausanne (École polytechnique fédérale de Lausanne, abbr. EPFL). The company will make one million euros available for new research projects in key technology fields such as biomedical research, ... more

Breaking new territory analyzing DNA modifications in glioblastoma

Using state-of-the-art molecular biology and statistical approaches, researchers at Dartmouth's Norris Cotton Cancer Center (NCCC) have identified the functional role of two distinct DNA modifications in glioblastoma (GBM) tissues. The signature of one of these pattern disruptions in partic ... more

analytica 2018: Preparations for the upcoming exhibition are underway

Exhibitors can now register for analytica 2018. As the leading international trade fair for the analysis, laboratory technology and biotechnology industry, analytica has been a gathering for decision-makers and users in the laboratory community for 50 years. The next edition of analytica ta ... more

The birth of the brightest red glowing protein

The brightest red fluorescent protein ever, mScarlet, has just been engineered by researchers at the University of Amsterdam, the Institut de Biologie Structurale, IBS (CEA/CNRS/University Grenoble Alpes) and the European Synchrotron (ESRF) in France. mScarlet can be used to monitor the act ... more

First-ever Buyer-Seller Forum at analytica Vietnam

Having the right contacts and a good network are indispensible in the business world. To help exhibitors and visitors make business contacts that suit them to a tee, for the first time ever analytica 2017 will feature a platform for pre-arranged meetings at a Buyer-Seller Forum. The Buyer-S ... more

Catching molecular dance moves in slow motion by adding white noise

In extreme slow-motion, a molecule of medicine entering a cell receptor would look a little like a Soyuz space capsule docking at the International Space Station. It would brake here, boost there; rotate, translate and then, with a light jolt, lock into place. In real time, large molecules ... more

Nanopolymer-modified protein array can pinpoint hard-to-find cancer biomarker

A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases. Glycoproteins are formed when sugars attach to and modify a protein. In some cases, a combination of glycoproteins present in a sample ... more

Migraine breakthrough could lead to improved drugs

A PhD student at Xi'an Jiaotong-Liverpool University in Suzhou, China is carrying out work that could have a significant impact on drugs developed to prevent and treat migraines. Fan Bu's doctoral project has revealed a previously unknown mechanism, involving a protein within brain cells, w ... more

Behavior of sugar transport proteins visualized

A group of researchers led by Kazuya Kikuchi, professor at the Graduate School of Engineering, Osaka University, clarified the role of a N-glycan chain on glucose transporter type 4 (GLUT4) by developing a method for visualizing intracellular trafficking of proteins. The GLUT4 translocation ... more

All news on diagnostics

Watson-Marlow Fluid Technology Group acquires Aflex Hose Ltd

Watson-Marlow Fluid Technology Group has acquired Aflex Hose Limited and its subsidiary Aflex Hose USA LLC (Aflex) through its parent company Spirax-Sarco Engineering plc, for £61.4 million. Aflex, based in Halifax, England and with a sales/assembly operation in Pennsylvania, USA, specializ ... more

analytica 2018: Preparations for the upcoming exhibition are underway

Exhibitors can now register for analytica 2018. As the leading international trade fair for the analysis, laboratory technology and biotechnology industry, analytica has been a gathering for decision-makers and users in the laboratory community for 50 years. The next edition of analytica ta ... more

First-ever Buyer-Seller Forum at analytica Vietnam

Having the right contacts and a good network are indispensible in the business world. To help exhibitors and visitors make business contacts that suit them to a tee, for the first time ever analytica 2017 will feature a platform for pre-arranged meetings at a Buyer-Seller Forum. The Buyer-S ... more

Eppendorf acquires Calibration Technology

Hamburg-based Eppendorf AG acquired Calibration Technology Ltd, headquartered in the National Technology Park Limerick, Ireland, on November 1. The company will continue to be managed as a wholly owned subsidiary of Eppendorf AG by its current Managing Director, Brian Kelly. The acquisition ... more

Changes in the Management Board of Eppendorf AG

A partial rearranging of the responsibilities in the Management Board of Eppendorf AG will be taking effect in a move designed to further drive the successful implementation of the company's strategy. This includes the creation of a new Board position which will include Sales, Marketing and ... more

Sartorius Continues to Grow by Strong Double Digits

Earnings increased by around one-fourth

Sartorius closed the first nine months of 2016 with significant double-growth rates for sales revenue and earnings. "Both divisions are continuing to grow faster than their respective markets," stated Group CEO Dr. Joachim Kreuzburg, giving a positive summary of the Group's nine-month perfo ... more

analytica Anacon India and India Lab Expo 2016 in the starting blocks

Ninth edition expected to bring together more than 8,500 trade professionals

analytica Anacon India and India Lab Expo, leading trade fairs for laboratory technology, analysis, biotechnology and diagnostics is scheduled from October 20 to 22 at the HITEX Exhibition Center, Hyderabad. The trade fairs will bring together manufacturers, suppliers, business experts and ... more

labfolder signs agreement with Max Planck Society

Contract provides up to 11,000 Max Planck scientists access to use labfolder for digital laboratory data management

labfolder GmbH and the Max Planck Society announced a licensing agreement to provide up to 11,000 Max Planck scientists with labfolder's laboratory data management digital platform. This is the first time that a tool for digital laboratory data management is being provided across an entire ... more

Phenomenex to be Acquired by Danaher Corporation

Phenomenex Inc. announced it has signed a definitive agreement to be acquired by Danaher Corporation. Phenomenex will operate as a standalone operating company, retaining the Phenomenex brand, its personnel and site locations. "Phenomenex is a widely recognizable brand that we are proud to ... more

Thermo Fisher Scientific completes acquisition of FEI Company

Thermo Fisher Scientific Inc. announced that it has completed its acquisition of FEI Company, Inc. a manufacturer of high-performance electron microscopy, for $107.50 per share in cash, or a total purchase price of approximately $4.2 billion. The completion of the transaction follows the re ... more

All news on lab technology

Merck expands distribution agreement with Roche

Merck announced an expansion of its distribution alliance with Roche to include the polymerase chain reaction (PCR) and quantitative real-time PCR (qPCR) enzyme products of Kapa Biosystems, a company acquired by Roche in 2015. The addition of the Kapa portfolio strengthens Merck’s existing ... more

Drug delivery modification sidesteps allergic responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also ... more

Psilocybin eases existential anxiety in people with life-threatening cancer

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushroom ... more

Takeda to invest more than 100 million Euros in dengue vaccine manufacturing plant

Takeda Pharmaceutical Company Limited announced that it will invest more than 100 Million Euros to build a new manufacturing plant for its dengue vaccine candidate in Singen, Germany. This represents a major step by Takeda toward meeting important unmet needs in dengue prevention. According ... more

Breaking good

Daraprim, a drug essential to humanity, cheaply reproduced by school students

Sydney Grammar students, under the supervision of the University of Sydney and global members of the Open Source Malaria consortium, have reproduced an essential medicine in their high school laboratories. The drug, Daraprim, had been the subject of controversy when the price was hiked from ... more

FDA Accepts the Biologics License Application for Avelumab for Priority Review

Avelumab could be the first treatment indicated for patients with metastatic Merkel cell carcinoma

Merck and Pfizer Inc. announced that the US Food and Drug Administration (FDA) has accepted for Priority Review the Biologics License Application (BLA) for avelumab, which was submitted by EMD Serono, the biopharmaceutical business of Merck in the US and Canada. This review relates to avelu ... more

Zika & Chikungunya Vaccine Development Boosted By Cash Injection

Themis Bioscience successfully closed 10 Mio EUR financing round

Themis Bioscience successfully closed a Series B financing round of 10 Mio Euro. The fresh capital will be used to complete a phase 2 clinical trial of its lead product, a vaccine candidate against Chikungunya fever. Further products that will benefit include the company's Zika virus vaccin ... more

Targeting breast cancer metabolism to fight the disease

How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. "Our finding is part of a growing interest in studying the metabolic function of cancer," says Ubald ... more

Multi-organ platform for risk assessment of nanomaterials

Multimodular microchip platform for predicting the behaviour of nanomaterials in the body

Nanomaterials are already part of everyday life in our modern society. New applications, along with continuously rising quantities being produced, have led to an increased exposure to nanomaterials for both people and the environment. Predicting the behaviour of nanomaterials in organisms a ... more

Rapid synthesis towards optically active alpha-aminocarbonyl therapeutics

New catalytic asymmetric reaction directly installs amines into carbonyl compounds

A team of organic chemists at ITbM, Nagoya University, has developed a new reaction to directly install amines into carbonyl compounds using their unique phase-transfer catalyst. This unprecedented method leads to the rapid formation of optically active (chiral) α-aminocarbonyls, which are ... more

All news on pharma

New strategy may drop cancer's guard

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists. Rice bioscientist Daniel Carson and alumna Micaela Morgado re ... more

Drug delivery modification sidesteps allergic responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also ... more

Danaher announces leadership appointment

Danaher Corporation announced that effective January 1, 2017, Rainer Blair has been promoted to Executive Vice President of Danaher Corporation, with responsibility for the Company's $5 billion Life Sciences platform. Mr. Blair, 52 years old, has served in a series of progressively more res ... more

Psilocybin eases existential anxiety in people with life-threatening cancer

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushroom ... more

New insights into skin cells could explain why our skin doesn't leak

The discovery of the shape and binding capability of epidermal cells could explain how skin maintains a barrier even when it is shedding. The authors of the study say their new understanding of how epidermal cells form a barrier may explain the paradox of how we can shed them without compro ... more

Potential new tool to aid breast cancer surgery

University of Adelaide researchers have developed an s that distinguishes breast cancer tissue from normal tissue - potentially allowing surgeons to be much more precise when removing breast cancer. The device could help prevent follow-up surgery, currently needed for 15-20% of breast cance ... more

Breaking good

Daraprim, a drug essential to humanity, cheaply reproduced by school students

Sydney Grammar students, under the supervision of the University of Sydney and global members of the Open Source Malaria consortium, have reproduced an essential medicine in their high school laboratories. The drug, Daraprim, had been the subject of controversy when the price was hiked from ... more

Creation of micro muscles aids better understanding of muscle efficiency

A biomedical research scientist is taking the lead in the creation of muscle cells and micro muscles to test muscle efficiency in the laboratory - and he is able to carry out this new and innovative work thanks to the support he has received to get him back into science after a career break ... more

Successfully Treating Genetically Determined Autoimmune Enteritis

Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation. This report comes from researchers at the Department of Biomedicine of the University of Basel and University Hospital Basel. Their results raise n ... more

Sometimes just watching hurts - and the signs of pain are seen in the brain

Some people claim to experience pain just watching something painful to happen. This is true especially of people suffering from complex regional pain syndrome (CRPS), a disabling chronic pain disorder in a limb. In CPRS patients, both own movements and just observing other persons' movemen ... more

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