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Evotec and Medicines For Malaria Venture announce a long-term compound management collaboration

Evotec AG announced the start of a multi-year compound management agreement between Evotec (US) Inc. and Medicines for Malaria Venture ("MMV") in support of MMV's Malaria and Pathogen Box initiatives. These two initiatives are expected to revolutionise the field of drug discovery for malari ... more

Zebrafish help to unravel Alzheimer’s disease

New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study by scientists at VIB and KU Leuven will identify the molecules responsible for this p ... more

Efficient production of hydrogen by algae

Microalgae need only sunlight and water for the production of hydrogen. However, in order to make hydrogen production by microalgae economically feasible their efficiency has to be increased by 1-2 orders of magnitude. In the current issue of Energy and Environmental Science scientists from ... more

500 million year reset for the immune system

Scientists at the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg re-activated expression of an ancient gene, which is not normally expressed in the mammalian immune system, and found that the animals developed a fish-like thymus. To the researchers surprise, whil ... more

Analytik Jena Closed Third Quarter Below Expectations

Analytik Jena AG closed the third quarter 2013/2014 below expectations. After nine months in the financial year 2013/2014, the Thuringian manufacturer of analytical measuring technology, life science instruments and optoelectronics generated consolidated revenue of EUR 89.7 m (previous year ... more

Stem cells reveal how illness-linked genetic variation affects neurons

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports. The study, led by Guo-li Ming, M.D., Ph.D., and Hongjun Song, Ph.D., of the Johns Hopkins University School o ... more

The Combined Nanoscopy Technique

Molecular processes in living cells can best be monitored by high-resolution microscopy techniques. Although groundbreaking technical innovations in the field of microscopy have been made in the past, frontiers still exist. Prof. Dr. Silvio O. Rizzoli and his team of the Göttingen DFG Resea ... more

Epigenetic breakthrough bolsters understanding of Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease. Epigenetic changes affect the expression or activity of genes without chan ... more

Microchip reveals how tumor cells transition to invasion

Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body. The epithelial-mesenchymal transition (EMT) is a process in which epithelial cells, which ... more

Miltenyi Biotec acquires gene therapy assets from Lentigen Corporation

Miltenyi Biotec announced that it has acquired the lentiviral vector manufacturing business and related assets from US company Lentigen Corporation, a global leader in lentiviral technology for cell and gene therapy applications. The acquisition further strengthens Miltenyi Biotec’s portfol ... more

All news

Is the Ebola Virus a Real Threat for Europe and the US?

“The Zaire Ebola virus causes a highly contagious and lethal hemorrhagic fever leading to the death of the infected individuals. The recent outbreak of the virus in West Africa has alarmed the world, especially Europe and the US, owing to the geographical speed of the infection spread and h ... more

Malvern Instruments completes acquisitions

Malvern Instruments Ltd has announced that it has completed the acquisition of MicroCal from GE Healthcare Life Sciences and has also purchased the Archimedes particle characterization system from Affinity Biosensors LLC (Santa Barbara, CA). Both of these developments extend Malvern’s portf ... more

QIAGEN adds promising genomic biomarkers to pipeline

QIAGEN N.V. announced it has acquired an exclusive global license to the biomarker SF3B1 from the University of Tokyo. SF3B1 is believed to play a critical role in the prognosis of patients with myelodysplastic syndromes (MDS), a group of hematological cancers in which bone marrow does not ... more

Zenith Epigenetics Appoints Julie Cherrington as President and CEO

Zenith Epigenetics Corp. announced that it has appointed Julie Cherrington PhD to act as the President and Chief Executive Officer of Zenith Epigenetics Corp. Julie has an extensive background leading companies focused on the discovery and development of novel cancer therapeutics and is wel ... more

GENALICE and deCODE Genetics enter into a partnership for population wide genomic analysis

GENALICE announced it is partnering with deCODE Genetics to facilitate the large-scale testing of its unique DNA data processing software solution, GENALICE MAP. After a first successful round of evaluating GENALICE MAP on speed and quality, both parties agreed to extend the evaluation to i ... more

Ötzi’s “non-human” DNA

Ötzi’s human genome was decoded from a hip bone sample taken from the 5,300 year old mummy. However the tiny sample weighing no more than 0.1 g provides so much more information. A team of scientists from EURAC in Bolzano/Bozen together with colleagues from the University of Vienna successf ... more

Pseudogenes may provide clearer understanding of biomarkers

Alas, the thankless pseudogene. Dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism's survival and are the "last stop" for removal of genomic waste. Not any mor ... more

Identifying microbial species

Millions of microbial species populate the world, but so far only a few have been identified due to the inability of most microbes to grow in the laboratory. Edgar Goluch, an engineer, and Slava Epstein, a biologist, aim to change this. The pair, both researchers at Northeastern University, ... more

Prototype electrolyte sensor to provide immediate read-outs

Patients trying to navigate today's complex medical system with its costly laboratory analyses might prefer a pain-free home diagnostic device, worn on the wrist, that can analyze, continuously record and immediately remedy low electrolyte levels.Runners, athletes in other strenuous sports ... more

Agilent Technologies Thought Leader Award Supports Dr. Carolyn Mountford

Agilent Technologies Inc. announced that Dr. Carolyn Mountford has received an Agilent Thought Leader Award in recognition of her work using nuclear magnetic resonance (NMR) spectroscopy technology in cancer research.Dr. Mountford is a professor of radiology at The University of Newcastle A ... more

All news on bioanalytics

Efficient production of hydrogen by algae

Microalgae need only sunlight and water for the production of hydrogen. However, in order to make hydrogen production by microalgae economically feasible their efficiency has to be increased by 1-2 orders of magnitude. In the current issue of Energy and Environmental Science scientists from ... more

Miltenyi Biotec acquires gene therapy assets from Lentigen Corporation

Miltenyi Biotec announced that it has acquired the lentiviral vector manufacturing business and related assets from US company Lentigen Corporation, a global leader in lentiviral technology for cell and gene therapy applications. The acquisition further strengthens Miltenyi Biotec’s portfol ... more

Reprocell acquires Reinnervate and BioServe

Reinnervate Ltd has been acquired by Reprocell of Shin-Yokohama in Japan. Reprocell, a pioneer in the field of induced pluripotent stem cell biology supplies iPSC-dervided Hepatocytes, Neurons and Cardiomyocytes as well as a range of media and reagents for stem cell culture. Reprocell inten ... more

Stem cells from nerves form teeth

Researchers at Karolinska Institutet in Sweden have discovered that stem cells inside the soft tissues of the tooth come from an unexpected source, namely nerves. These findings are now being published in the journal Nature and contribute to brand new knowledge of how teeth are formed, how ... more

Genetics of cancer: Non-coding DNA can finally be decoded

Cancer is a disease of the genome resulting from a combination of genetic modifications (or mutations). We inherit from our parents strong or weak predispositions to developing certain kinds of cancer; in addition, we also accumulate new mutations in our cells throughout our lifetime. Altho ... more

Spinach could lead to alternative energy more powerful than Popeye

Spinach gave Popeye super strength, but it also holds the promise of a different power for a group of scientists: the ability to convert sunlight into a clean, efficient alternative fuel. Purdue University physicists are part of an international group using spinach to study the proteins inv ... more

Genticel granted five new patents in the US and Asia during first half of 2014

Genticel has been granted five patents in major territories since the beginning of 2014. These patents consolidate Genticel’s product pipeline in important emerging and mature pharmaceutical markets. The patents US 8628779, IN 258906 and KR 10-1382250, granted in the USA, India and South K ... more

Temple University researchers eliminate the HIV virus from cultured human cells for first time

The HIV-1 virus has proved to be tenacious, inserting its genome permanently into its victims' DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip ou ... more

Diseases of another kind

The drought that has the entire country in its grip is affecting more than the color of people's lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer ... more

New view of stomach cancer could hasten better therapies

In a massive effort to catalog the molecular causes of stomach cancer, scientists, including researchers at Dana-Farber Cancer Institute, have identified four subtypes of tumors based on shared mutations and other molecular abnormalities. They say the new classification promises to advance ... more

All news on biotechnology

Predemtec GmbH receives seed financing for developing a blood test to diagnose Alzheimer`s Disease

Predemtec GmbH develops a blood test for a reliable diagnosis of Alzheimer’s disease. In July 2014 the start-up received a seed financing from High-Tech Gruenderfonds (HTGF). The seed investment will be used to finalize the first test into a marketable product and to expand the scope of the ... more

QIAGEN adds promising genomic biomarkers to pipeline

QIAGEN N.V. announced it has acquired an exclusive global license to the biomarker SF3B1 from the University of Tokyo. SF3B1 is believed to play a critical role in the prognosis of patients with myelodysplastic syndromes (MDS), a group of hematological cancers in which bone marrow does not ... more

Implandata Announces Successful Implantation of Micro-Sensor for Intraocular Pressure Measurement in Glaucoma Patient

Implandata Ophthalmic Products GmbH reports the successful implantation of the first patient within the ARGOS-02 clinical study at Augenklinik Bellevue in Kiel, Germany.  In the ARGOS-02 clinical study, six eye centers in Germany are currently recruiting primary open angle glaucoma patients ... more

Dangers of desert dust: New diagnostic tool for valley fever

On July 5, 2011, a massive wall of dust, ("haboob," in Arabic), blanketed Phoenix, Arizona, creating an awesome spectacle, (or stubborn nuisance, depending on your perspective). Dust storms are a common occurrence in the arid desert environments of the American Southwest. But windborne dust ... more

New blood test identifies risk “Sudden Cardiac Death”

UAntwerp (University of Antwerp), UZA (Antwerp University Hospital), and Multiplicom NV together developed a blood test to determine the genetic risk of “Sudden Cardiac Death” (SCD). This test, called PED MASTR, is already in use at the center of medical genetics of UZA/UAntwerp and will be ... more

Merck to Collaborate with Sysmex Inostics on a Blood-Based RAS Biomarker Test

Merck announced that the company has signed an agreement to collaborate with Sysmex Inostics GmbH for the development and commercialization of a blood-based RAS biomarker test for patients with metastatic colorectal cancer (mCRC). Blood-based biomarker testing is a faster and easier approac ... more

Studies Validate EKF Diagnostics’ Early Stage Test for Progressive Diabetic Kidney Disease

EKF Diagnostics confirmed the growing weight of independent scientific evidence as validation that soluble TNF Receptors 1 and 2 are strong biomarkers of progressive Diabetic Kidney Disease (DKD). EKF affirms that the markers can be reliably used as diagnostic tests to predict end-stage ren ... more

Research that more than meets the eye

The link between blood flow in the retina and the development of glaucoma can now be measured accurately for the first time. This was made possible by the further development of an established measurement method, optical coherence tomography (OCT), which enables the visual assessment of the ... more

Research combines graphene and painkiller receptor

Almost every biological process involves sensing the presence of a certain chemical. Finely tuned over millions of years of evolution, the body’s different receptors are shaped to accept certain target chemicals. When they bind, the receptors tell their host cells to produce nerve impulses, ... more

Exact outline of melanoma could lead to new diagnostic tools

Researchers at Oregon State University have identified a specific biochemical process that can cause normal and healthy skin cells to transform into cancerous melanoma cells, which should help predict melanoma vulnerability and could also lead to future therapies. More than 70,000 cases of ... more

All news on diagnostics

Bochem Increasingly Using New Media

Bochem Instrumente GmbH presents sections of its overall product spectrum in various new videos. The recently finished productions provide a compact overview of the product groups of lab jacks, electrical lifts, containers as well as stands and clamps. They can be found on the company’s web ... more

Merger of CyBio AG into Analytik Jena AG Completed

The merger of CyBio AG into Analytik Jena AG became effective upon entry into the commercial register of Analytik Jena AG (commercial register of the Registry Court of Jena, HRB 200027). As a result, CyBio AG is dissolved as an independent company. In the future, the Life Science business u ... more

LABVOLUTION – the new lab technology show in Hannover

Deutsche Messe is launching LABVOLUTION, a new trade fair to be staged every two years as amajor platform for the world of lab technology and equipment. LABVOLUTIONmakes its debut from 6 to 8 October 2015 at the Hannover Exhibition Center in Hannover, Germany, where it will take place every ... more

Automating Laboratory-On-A-Chip To Cut Healthcare Costs

A research team at the University of California, Riverside has created a computer programming language that will automate “laboratory-on-a-chip” technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.“If you think of the beginning of computers ... more

Reorganization of the Executive Board of Eppendorf AG

The Executive Board of Eppendorf AG is reshaping in order to be optimally equipped to meet the future demands of the market. Dr. Dirk Ehlers, Chairman of the Executive Board of the Eppendorf Group, will leave the company by mutual agreement. Detmar Ammermann (Chief Financial Officer) will r ... more

New microscope sees what others can't

Microscopes don't exactly lie, but their limitations affect the truths they can tell. For example, scanning electron microscopes (SEMs) simply can't see materials that don't conduct electricity very well, and their high energies can actually damage some types of samples. In an effort to ext ... more

A lab in your pocket

When you get sick, your physician may take a sample of your blood, send it to the lab and wait for results. In the near future, however, doctors may be able to run those tests almost instantly on a piece of plastic about the size of credit card. These labs-on-a-chip would not only be quick— ... more

Sartorius with Gains

Sartorius got off to a good start in fiscal 2014, with gains in order intake and sales revenue. In constant currencies, Group sales revenue rose 6.3% and order intake increased 4.9%. Despite negative currency impacts, operating Profit for the Group also grew 2.0%; its respective margin afte ... more

Turning smart phones into microscopes

Australian scientists have invented a simple and cheap way of making a high-powered lens that can transform a smart phone into a high-resolution microscope. Costing less than a cent, the lenses promise a revolution in science and medicine in developing countries and remote areas. The lens f ... more

analytica Vietnam 2015: Vietnam's economy continues to grow

According to Germany Trade & Invest (GTAI), the German association for foreign investment and location marketing, Vietnam plans to become a modern industrial nation by the year 2020. In addition, the southeast Asian threshold country is currently negotiating free trade agreements, amongst o ... more

All news on lab technology

Evotec and Medicines For Malaria Venture announce a long-term compound management collaboration

Evotec AG announced the start of a multi-year compound management agreement between Evotec (US) Inc. and Medicines for Malaria Venture ("MMV") in support of MMV's Malaria and Pathogen Box initiatives. These two initiatives are expected to revolutionise the field of drug discovery for malari ... more

Merck Reports Organic Growth in all Four Businesses in Second Quarter

Merck generated organic sales growth of 3.4% in the second quarter of 2014. In addition, the company reported an acquisition-related sales increase of 3.0%, which was countered by negative foreign exchange effects of -4.5%. Overall, sales thus increased moderately by € 52 million or 1.9% to ... more

Where scientists from abroad want to conduct research

The universities in the major conurbations Berlin and Munich are in particular demand among foreign researchers according to the Humboldt Rankings released today. The ranking list shows how many researchers have come to Germany on a fellowship from the Humboldt Foundation in the last five y ... more

Assessment of pain and suffering in test animals

New rules in the European Union (EU) for the protection of laboratory animals require assessment of pain that these animals may experience during scientific experiments. The Federal Institute for Risk Assessment (BfR) published an article in the science magazine "Nature" about the national ... more

EU approves Roche’s Avastin for platinum-resistant recurrent ovarian cancer

Roche announced that the European Commission (EU) approved the use of Avastin (bevacizumab) in combination with paclitaxel, topotecan, or pegylated liposomal doxorubicin chemotherapy as a treatment for women with recurrent ovarian cancer that is resistant to platinum-containing chemotherapy ... more

Roche to acquire Santaris Pharma

Roche announced that it has agreed to acquire Santaris Pharma. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. This new class of medicines has the potential to address difficult to treat ... more

Galapagos receives milestone in osteoarthritis alliance with Servier

Galapagos NV announced the achievement of a second partial milestone, thereby completing the nomination of a new pre-clinical candidate in the osteoarthritis alliance with Servier. On March 7, Galapagos announced the receipt of €2M as the first partial milestone. Today's payment remains und ... more

A Treatment Revolution is Underway: All-Oral Therapies Transform Global Hepatitis C Antiviral Market

Drug development for hepatitis C virus (HCV) antivirals has amplified with rising incidence rates and the intense need for curative therapy in the absence of a preventative vaccine. Change is underway as the market moves away from protease inhibitors and interferon regimens towards highly e ... more

NOXXON Initiates Phase IIa Study of Anti-Hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94)

NOXXON Pharma announced the treatment of a first patient with its anti-hepcidin Spiegelmer® lexaptepid pegol (NOX-H94) in a phase IIa proof - of - concept clinical trial to treat erythropoietin (EPO) - hyporesponsive anemia in dialysis patients. This is the fourth clinical trial with lexapt ... more

Evotec receives first milestones in TargetAD collaboration

Evotec AG announced the successful achievement of the first milestones in its TargetAD collaboration with Janssen Pharmaceuticals, Inc. ("Janssen") for the identification and selection of three selected targets from the TargetADdatabase. These target selections were achieved under the agree ... more

All news on pharma

Zebrafish help to unravel Alzheimer’s disease

New fundamental knowledge about the regulation of stem cells in the nerve tissue of zebrafish embryos results in surprising insights into neurodegenerative disease processes in the human brain. A new study by scientists at VIB and KU Leuven will identify the molecules responsible for this p ... more

Stem cells reveal how illness-linked genetic variation affects neurons

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports. The study, led by Guo-li Ming, M.D., Ph.D., and Hongjun Song, Ph.D., of the Johns Hopkins University School o ... more

Epigenetic breakthrough bolsters understanding of Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease. Epigenetic changes affect the expression or activity of genes without chan ... more

Microchip reveals how tumor cells transition to invasion

Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body. The epithelial-mesenchymal transition (EMT) is a process in which epithelial cells, which ... more

Long Antibiotic Treatments: Slowly Growing Bacteria to Blame

Whether pneumonia or sepsis – infectious diseases are becoming increasingly difficult to treat. One reason for this is the growing antibiotic resistance. But even non-resistant bacteria can survive antibiotics for some time, and that’s why treatments need to be continued for several days or ... more

Disruption of gut bacteria early in life can lead to obesity in adulthood

Certain microbes found in the gut may protect against obesity and diabetes. A study published by Cell Press August 14th in the journal Cell reveals that these microbes shape their hosts' metabolism very early in life and that disrupting them with short-term exposure to antibiotics during in ... more

RNA-targeted drug candidate for Lou Gehrig's disease found

By targeting RNA molecules that tangle and clump in the nervous systems of patients with the most common genetic form of amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease) and frontotemporal dementia (FTD), researchers have shown they can effectively limit those damaging elements i ... more

New weapon of the immune system discovered

Max Planck researchers have discovered a completely new way in which the immune system recognizes pathogens. The aryl hydrocarbon receptor has long been a focus of research for pharma-cologists and toxicologists, as it recognizes environmental toxins. However, it also plays an important rol ... more

Researchers uncover how Ebola virus disables immune response

The Ebola outbreak in West Africa has brought a lot of attention to the deadly virus. According to the World Health Organization, up to 90% of those infected with Ebola die from the virus. Now, researchers publishing August 13 in the Cell Press journal Cell Host & Microbe reveal how Ebola b ... more

Protein found to block benefits of vitamin A cancer therapy

Retinoic acid is a form of vitamin A that is used to treat and help prevent the recurrence of a variety of cancers, but for some patients the drug is not effective. The reason for this resistance was unclear until this week when researchers from Virginia Commonwealth University (VCU) Massey ... more

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