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Sanofi and Regeneron Announce Start of Phase 3 Study of Dupilumab in Patients with Atopic Dermatitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced that the first patients have been dosed in a Phase 3 clinical study of dupilumab, an investigational therapy that blocks IL-4 and IL-13 signaling, in adults with moderate-to-severe atopic dermatitis (AD) that is not adequately controlled ... more

Earlier unknown molecular-level mechanism may contribute to the growth rate of breast cancer

Researchers at VTT Technical Research Centre of Finland, the University of Turku and the University of Oslo have discovered a previously unknown molecular-level mechanism that may partly explain the increased growth of cancer cells. The study, published in the British Journal of Cancer, sho ... more

New perspectives for development of an RSV vaccine

Respiratory Syncytial Virus causes severe respiratory tract infections and worldwide claims the lives of 160,000 children each year. Scientists at VIB and Ghent University have succeeded in developing a promising vaccination strategy to counteract this common virus infection. Xavier Saelens ... more

Start signal for transcription of stressed genes identified

What happens when a cell is stressed? In their latest study, Christian Seiserand his team at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna addressed this question. They identified which genes of the cell are activated under stress, sh ... more

Adenosine can melt "love handles"

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer's disease. For this reason, many people dream of an efficient method for losing weight. An international team of researchers led by Profe ... more

Researchers Identify “Naïve-Like” Human Stem Cells

In their search for the earliest possible stage of development of human embryonic stem cells (hESCs) that still have the potential to develop into any types of body cells and tissue, researchers from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, and the Universi ... more

Sugared soda consumption, cell aging associated in new study

Sugar-sweetened soda consumption might promote disease independently from its role in obesity, according to UC San Francisco researchers who found in a new study that drinking sugary drinks was associated with cell aging. The study revealed that telomeres — the protective units of DNA that ... more

How a molecular Superman protects the genome from damage

How many times have we seen Superman swoop down from the heavens and rescue a would-be victim from a rapidly oncoming train? It's a familiar scenario, played out hundreds of times in the movies. But the dramatic scene is reenacted in real life every time a cell divides. In order for divisio ... more

Immune cells in the liver drive fatty liver disease and liver cancer

Immune cells that migrate to the liver and interact there with liver tissue cells get activated by metabolic stress (e.g. through lipids of a high fat diet) and drive the development of fatty liver disease, non-alcoholic steatohepatitis and liver cancer. Scientists from the Helmholtz Zentru ... more

Sucessful Spin-Out of ImevaX GmbH from the Technische Universität München

ImevaX GmbH commenced its research and development activities in their own premises in Munich on Sep. 1st, 2014. With this step, ImevaX realized a successful spin-out from the Technische Universität München (TUM). A key factor for the success of the founder Professor Markus Gerhard and his ... more

All news

New sequencing reveals genetic history of tomatoes

An international team of researchers, led by the Chinese Academy of Agricultural Sciences in Beijing, published in the journal Nature Genetics a brief genomic history of tomato breeding, based on sequencing of 360 varieties of the tomato plant. The C.M. Rick Tomato Genetics Resource Center ... more

Eurofins Genomics Extends Its Genomic Business In Italy

Eurofins Genomics, the genomics division of the Eurofins Scientific Group, has now established its own subsidiary in Italy, located in Vimodrone, Milan. With the acquisition of the oligonucleotide synthesis and DNA sequencing business from Primm S.r.l. in June this year and the decision to ... more

Bibby Scientific Ltd acquires PCRmax Ltd

Bibby Scientific has purchased 100% of the share capital of PCRmax, a UK based sales and distribution Company set up specifically to capture a significant market share of the standard (PCR) and quantitative PCR (QPCR) markets. They are also the registered owners of the intellectual property ... more

Genetic Makeup of Europeans

The beginning of agriculture and animal domestication, which began in the Near East before 11,000 years ago, had a tremendous impact on human lifestyle. Hunter-gatherers were replaced in many places by sedentary farmers, and there were large increases in population size that laid the founda ... more

Gibbon genome sequenced

An international team of researchers that includes Christian Roos, Markus Brameier and Lutz Walter from the German Primate Center (DPZ) in Göttingen, have decoded the genome of gibbons from Southeast Asia. With this, the entire genetic information of five different species of this primate f ... more

Highly automated live cell imaging speeds up the search for new drugs

Fraunhofer FIT will present the latest version of its Zeta Fluorescence Image Analysis software at MipTec. Zeta, now extended to a software platform, supports the complete work process of finding new pharmaceutical agents. At MipTec, Fraunhofer FIT will demo advanced Zeta applications in ca ... more

Is the Ebola Virus a Real Threat for Europe and the US?

“The Zaire Ebola virus causes a highly contagious and lethal hemorrhagic fever leading to the death of the infected individuals. The recent outbreak of the virus in West Africa has alarmed the world, especially Europe and the US, owing to the geographical speed of the infection spread and h ... more

Malvern Instruments completes acquisitions

Malvern Instruments Ltd has announced that it has completed the acquisition of MicroCal from GE Healthcare Life Sciences and has also purchased the Archimedes particle characterization system from Affinity Biosensors LLC (Santa Barbara, CA). Both of these developments extend Malvern’s portf ... more

QIAGEN adds promising genomic biomarkers to pipeline

QIAGEN N.V. announced it has acquired an exclusive global license to the biomarker SF3B1 from the University of Tokyo. SF3B1 is believed to play a critical role in the prognosis of patients with myelodysplastic syndromes (MDS), a group of hematological cancers in which bone marrow does not ... more

Zenith Epigenetics Appoints Julie Cherrington as President and CEO

Zenith Epigenetics Corp. announced that it has appointed Julie Cherrington PhD to act as the President and Chief Executive Officer of Zenith Epigenetics Corp. Julie has an extensive background leading companies focused on the discovery and development of novel cancer therapeutics and is wel ... more

All news on bioanalytics

Success with science and demo videos on YouTube - it can be achieved!

More and more life science organisations and companies place their videos on YouTube, but most of these are rarely watched. Over the first year online, many struggle to reach more than a few hundred views. However, a video explaining the complex phenomenon of the honey bee’s waggle dance, p ... more

analytica China 2014: Closed with overall success

On September 26 analytica China 2014 closed with record-breaking visitor numbers: 18,775 business professionals (2012: 16,940) from 62 countries attended the seventh edition of Chinas Leading Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics at the Shanghai New I ... more

Fertilizer and Fuel

Plants need nitrogen and carbon to grow. Photosynthesis allows them to take in the latter directly from the air, but they have to procure nitrogen through their roots in the form of organic molecules like ammonia or urea. Even though nitrogen gas makes up approximately 80 percent of Earth’s ... more

Algae deliver hydrogen

Hydrogen as a regenerative fuel produced in gigantic water tanks full of algae, which need nothing more than sunlight to produce the promising green energy carrier: a great idea in theory, but one that fails due to the vast amount of space required for the production process. Scientists fro ... more

BRAIN and FUCHS Europe in partnership to produce lubricants from renewable raw materials

BRAIN AG and FUCHS Europe Schmierstoffe GmbH announce a partnership involving the biotechnological production of lubricant additives from renewable resources. Throughout the previous year, this successful partnership was a part of the Federal Ministry of Education and Research (BMBF) strate ... more

Merck to Acquire Sigma-Aldrich to Enhance Position in Attractive Life Science Industry

Merck and Sigma-Aldrich announced that they have entered into a definitive agreement under which Merck will acquire Sigma-Aldrich for $17.0 billion (€13.1 billion), establishing one of the leading players in the $130 billion global life science industry. Merck will acquire all of the outsta ... more

BASF, Cargill and Novozymes achieved another milestone in bio-based acrylic acid

BASF, Cargill and Novozymes announced the achievement of another milestone in their joint development of technologies to produce acrylic acid from renewable raw materials. The team has demonstrated the successful conversion of 3-hydroxypropionic acid (3-HP), to glacial acrylic acid and supe ... more

Diabetes researchers find faster way to create insulin-producing cells

University of British Columbia, in collaboration with BetaLogics Venture, a division of Janssen Research & Development, LLC, has published a study highlighting a protocol to convert stem cells into insulin-producing cells. The new procedure could be an important step in the fight against Ty ... more

Central biobank for drug research

For the development of new drugs it is crucial to work with stem cells, as these allow scientists to study the effects of new active pharmaceutical ingredients. But it has always been difficult to derive enough stem cells of the right quality and in the right timeframe. A central biobank is ... more

IMGM Laboratories GmbH announces the appointment of Dr. Michael Bonin as Managing Director

The genomic service provider IMGM Laboratories GmbH is pleased to announce Dr. Michael Bonin (40) as additional Managing Director effective August 1st 2014. Michael Bonin will head the scientific and technical development of the IMGM Laboratories GmbH activities and will direct the business ... more

All news on biotechnology

Earlier unknown molecular-level mechanism may contribute to the growth rate of breast cancer

Researchers at VTT Technical Research Centre of Finland, the University of Turku and the University of Oslo have discovered a previously unknown molecular-level mechanism that may partly explain the increased growth of cancer cells. The study, published in the British Journal of Cancer, sho ... more

New clues for the early detection of colorectal cancer

Researchers at the University of Luxembourg have identified potential new ways to test for the first signs of one of the most deadly types of cancer: colorectal cancer. They have found new “biomarkers”: molecules whose increased presence or absence in tissue suggests the development of tumo ... more

New blood test determines whether you have or are likely to get cancer

A new research report published in the October 2014 issue of The FASEB Journal may make the early detection of cancer as easy as a simple blood test. This test, called the "lymphocyte genome sensitivity" (LGS) test, could not only detect some cancers earlier than ever before, but it may eli ... more

'Virtual breast' could improve cancer detection

Next to lung cancer, breast cancer is the leading cause of cancer death in women, according to the American Cancer Society. That's why so many medical professionals encourage women to get mammograms, even though the tests are imperfect at best: only a minority of suspicious mammograms actua ... more

analytica China 2014: Closed with overall success

On September 26 analytica China 2014 closed with record-breaking visitor numbers: 18,775 business professionals (2012: 16,940) from 62 countries attended the seventh edition of Chinas Leading Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics at the Shanghai New I ... more

Innovative image sensing technology for early diagnosis of diabetes and Alzheimer’s disease

Professor Kazuaki Sawada and Dr. Takigawa of the National Center for Geriatrics and Gerontology and colleagues at Toyohashi University of Technology have established an easy to use, low-cost, rapid, and high sensitivity semiconductor-imaging based medical diagnostic biosensing system for an ... more

Mechanism of Parkinson's spread demonstrated

An international, interdisciplinary group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has demonstrated, through the use of a new antibody, how Parkinson's disease spreads from cell to cell in the human brain.Until now, this mechanism h ... more

New diagnostic method identifies genetic diseases

People with genetic diseases often have to embark on an odyssey from one doctor to the next. Fewer than half of all patients who are suspected of having a genetic disease actually receive a satisfactory diagnosis. Scientists from the Charité - Universitätsmedizin Berlin and the Max Planck I ... more

The shadow of a disease

In future, some diseases might be diagnosed earlier and treated more effectively. Researchers at the Max Planck Institute for the Science of Light in Erlangen have developed an optical method that makes individual proteins, such as the proteins characteristic of some cancers, visible. Other ... more

Mice and men share a diabetes gene

A joint work by EPFL, ETH Zürich and the CHUV has identified a pathological process that takes place in both mice and humans towards one of the most common diseases that people face in the industrialized world: type 2 diabetes. This work was conducted in Johan Auwerx's (EPFL) and Ruedi Aebe ... more

All news on diagnostics

analytica China 2014: Closed with overall success

On September 26 analytica China 2014 closed with record-breaking visitor numbers: 18,775 business professionals (2012: 16,940) from 62 countries attended the seventh edition of Chinas Leading Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics at the Shanghai New I ... more

Messe München International takes over one of India's leading trade fairs for laboratory technology

Messe München International is strengthening its portfolio of events in the future market of India by taking over India Lab Expo, one of the leading trade fairs for laboratory technology, analysis and biotechnology on the Indian subcontinent. For the first time ever, this year's India Lab E ... more

Bochem Increasingly Using New Media

Bochem Instrumente GmbH presents sections of its overall product spectrum in various new videos. The recently finished productions provide a compact overview of the product groups of lab jacks, electrical lifts, containers as well as stands and clamps. They can be found on the company’s web ... more

Merger of CyBio AG into Analytik Jena AG Completed

The merger of CyBio AG into Analytik Jena AG became effective upon entry into the commercial register of Analytik Jena AG (commercial register of the Registry Court of Jena, HRB 200027). As a result, CyBio AG is dissolved as an independent company. In the future, the Life Science business u ... more

LABVOLUTION – the new lab technology show in Hannover

Deutsche Messe is launching LABVOLUTION, a new trade fair to be staged every two years as amajor platform for the world of lab technology and equipment. LABVOLUTIONmakes its debut from 6 to 8 October 2015 at the Hannover Exhibition Center in Hannover, Germany, where it will take place every ... more

Automating Laboratory-On-A-Chip To Cut Healthcare Costs

A research team at the University of California, Riverside has created a computer programming language that will automate “laboratory-on-a-chip” technologies used in DNA sequencing, drug discovery, virus detection and other biomedical applications.“If you think of the beginning of computers ... more

Reorganization of the Executive Board of Eppendorf AG

The Executive Board of Eppendorf AG is reshaping in order to be optimally equipped to meet the future demands of the market. Dr. Dirk Ehlers, Chairman of the Executive Board of the Eppendorf Group, will leave the company by mutual agreement. Detmar Ammermann (Chief Financial Officer) will r ... more

New microscope sees what others can't

Microscopes don't exactly lie, but their limitations affect the truths they can tell. For example, scanning electron microscopes (SEMs) simply can't see materials that don't conduct electricity very well, and their high energies can actually damage some types of samples. In an effort to ext ... more

A lab in your pocket

When you get sick, your physician may take a sample of your blood, send it to the lab and wait for results. In the near future, however, doctors may be able to run those tests almost instantly on a piece of plastic about the size of credit card. These labs-on-a-chip would not only be quick— ... more

Sartorius with Gains

Sartorius got off to a good start in fiscal 2014, with gains in order intake and sales revenue. In constant currencies, Group sales revenue rose 6.3% and order intake increased 4.9%. Despite negative currency impacts, operating Profit for the Group also grew 2.0%; its respective margin afte ... more

All news on lab technology

Sanofi and Regeneron Announce Start of Phase 3 Study of Dupilumab in Patients with Atopic Dermatitis

Sanofi and Regeneron Pharmaceuticals, Inc. announced that the first patients have been dosed in a Phase 3 clinical study of dupilumab, an investigational therapy that blocks IL-4 and IL-13 signaling, in adults with moderate-to-severe atopic dermatitis (AD) that is not adequately controlled ... more

New perspectives for development of an RSV vaccine

Respiratory Syncytial Virus causes severe respiratory tract infections and worldwide claims the lives of 160,000 children each year. Scientists at VIB and Ghent University have succeeded in developing a promising vaccination strategy to counteract this common virus infection. Xavier Saelens ... more

Sucessful Spin-Out of ImevaX GmbH from the Technische Universität München

ImevaX GmbH commenced its research and development activities in their own premises in Munich on Sep. 1st, 2014. With this step, ImevaX realized a successful spin-out from the Technische Universität München (TUM). A key factor for the success of the founder Professor Markus Gerhard and his ... more

Vetter Announces Personnel Changes in its Development Service Division

Vetter officially announced a series of adjustments to its Development Service related structures designed to support its customer base. Effective October 1, Dr. Susanne Resatz, formerly Manager Process Development and Manufacturing at the company’s clinical development facility in Chicago, ... more

WILEX subsidiary Heidelberg Pharma extends research collaboration with Roche

WILEX AG announced that WILEX subsidiary Heidelberg Pharma and Roche extended the existing 2013 licence agreement to apply the antibody drug conjugate (ADC) technology for the further development of Roche antibodies. The aim is to identify and develop novel AntibodyTargeted Amanitin Conjuga ... more

Aethlon Medical Announces First Treatment of an Ebola Patient

Aethlon Medical, Inc. announced the first use of Hemopurifier® therapy on a patient infected with Ebola virus. The treatment was administered to a Ugandan doctor at the Frankfurt University Hospital in Germany. The patient, who is also a World Health Organization (WHO) worker, contracted th ... more

New Oncology and Gustave Roussy Announce Collaboration on Genetic Testing

New Oncology announced that it has entered into a collaboration agreement with Gustave Roussy Cancer Campus, Paris. Under this agreement, New Oncology will perform comprehensive parallel multigene testing to identify therapeutically relevant alterations in cancer-related genes. New Oncology ... more

M+W Group Receives Major Contract for Merck's New Pharmaceutical Facility in China

M+W Group has been awarded a major order from Merck for its new pharmaceutical facility in China. The site with around 40,000 squaremeters is located in the Nantong Economical Technological Development area in the Greater Shanghai region. M+W Group will be responsible for the engineering de ... more

Merck Serono to Collaborate With The Institute of Cancer Research, London, and Wellcome Trust

Merck Serono, the biopharmaceutical division of Merck, The Institute of Cancer Research (ICR), and the Wellcome Trust, London, announced a co-development and license agreement building on two independent research programs at both the ICR and Merck Serono to identify inhibitors of tankyrase, ... more

New Medicines from the Arctic Ocean

The Lead Discovery Center GmbH (LDC), a renowned translational research organization, and UiT The Arctic University of Norway (UiT) have teamed up to discover new medicines from the marine arctic environment. The partners will focus on human diseases with high unmet medical need. UiT has ga ... more

All news on pharma

Earlier unknown molecular-level mechanism may contribute to the growth rate of breast cancer

Researchers at VTT Technical Research Centre of Finland, the University of Turku and the University of Oslo have discovered a previously unknown molecular-level mechanism that may partly explain the increased growth of cancer cells. The study, published in the British Journal of Cancer, sho ... more

Adenosine can melt "love handles"

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer's disease. For this reason, many people dream of an efficient method for losing weight. An international team of researchers led by Profe ... more

Sugared soda consumption, cell aging associated in new study

Sugar-sweetened soda consumption might promote disease independently from its role in obesity, according to UC San Francisco researchers who found in a new study that drinking sugary drinks was associated with cell aging. The study revealed that telomeres — the protective units of DNA that ... more

Immune cells in the liver drive fatty liver disease and liver cancer

Immune cells that migrate to the liver and interact there with liver tissue cells get activated by metabolic stress (e.g. through lipids of a high fat diet) and drive the development of fatty liver disease, non-alcoholic steatohepatitis and liver cancer. Scientists from the Helmholtz Zentru ... more

Study reveals optimal particle size for anticancer nanomedicines

Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy. Understanding the interdependency of physiochemical properties of nanomedicines, in correlation to their biological responses and function ... more

Effects of high-risk Parkinson's mutation are reversible

Researchers from the University of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson's. Mutations in a gene called LRRK2 carry a well-established risk for Parkinson's disease, however the basis for t ... more

Remotely controlled magnetic nanoparticles stimulate stem cells to regenerate better, denser bone

In a recent study published in STEM CELLS Translational Medicine, scientists have found what they believe might be a better way to regrow bone tissue using magnetic nanoparticles coated with targeting proteins that stimulate stem cells to regenerate the bone. They also were able to deliver ... more

Parkinson: How toxic proteins stress nerve cells

Parkinson's Disease is the second most common neurodegenerative disorder. In Germany alone, almost half a million people are affected. The focus of the disease is the progressive degeneration of dopamine-producing nerve cells in a certain region of the midbrain, the substantia nigra. Misfol ... more

Researchers characterise a new tumour syndrome

Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have published their findings that mutations in a gene known as “ARMC5” promote the growth of benign tumours in the adrenal glands and on the meninges: ARMC5 appears to belong to the group of ... more

Sonic Hedgehog protein causes DNA damage and the development child brain tumors

Scientists at the IRCM and the University of Montreal discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Frédéric Charron, PhD, found that a protein known as Sonic Hedgehog induces DNA damage, which cause ... more

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