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PRAC recommends restricting the use of codeine when used for pain relief in children

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended a series of measures to address safety concerns with codeine-containing medicines when used for the management of pain in children. This follows the PRAC’s review of reports of children who de ... more

An end to chasing structures that were never there

Research describes a rapid computational method for identifying incorrect molecular structures that have been mistakenly determined using misassigned NMR signals. Ariel Sarotti, a scientist in Argentina, has developed a tool that combines calculated and experimental 13C NMR data to flag up ... more

Psychiatric disorders linked to a protein involved in the formation of long-term memories

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia. The discovery was made by a team of scientists led by Alexei Morozov, an assistant professor at the Virginia Tech Carili ... more

Study finds racial and ethnic disparities in usage of specialty services for children with autism

A study from investigators at MassGeneral Hospital for Children (MGHfC) found that African-American or Hispanic children diagnosed with autism were significantly less likely than white children to have received subspecialty care or procedures related to conditions that often accompany autis ... more

Bacterium breaks down grass into biofuel

Research reports the discovery of the first microorganism that anaerobically degrades plant biomass, without the need for chemical pre-treatment, to produce raw materials that can be converted to biofuels. Scientists in the United States demonstrated that Caldicellulosiruptor bescii bacteri ... more

Presentation of the 2013 Eppendorf Award for Young European Investigators

The British scientist Ben Lehner, Ph.D., ICREA Research Professor, EMBL-CRG Systems Biology Unit at the Centre de Regulació Genòmica, in Barcelona, Spain, has won the 2013 Eppendorf Young Investigator Award. Lehner, born 1978, receives the Eppendorf Award for his discoveries concerning the ... more

PRAC recommends the same cardiovascular precautions for diclofenac as for selective COX-2 inhibitors

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that the effects of the painkiller diclofenac on the heart and circulation when given systemically (by means such as capsules, tablets or injections) are similar to those of selective COX-2 inhi ... more

Be gone, bacteria

Staph infections in hospitals are a serious concern, so much so that the term Methicillin-resistant Staphylococcus aureus (MRSA) is as commonly known as MRI. Far less known is that in many of these cases, patients are infecting themselves. In heart surgeries and knee and joint-replacement p ... more

Developmental protein plays role in spread of cancer

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Dieg ... more

Using math to kill cancer cells

Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications mi ... more

All news

Analytik Jena to develop products for sepsis diagnostics

Analytik Jena has acquired all of the assets of the insolvent company SIRS-Lab GmbH as part of an asset deal. SIRS-Lab, a company that develops molecular diagnostics methods and testing systems for life-threatening infections like sepsis, had filed for insolvency in December 2012. Analytik ... more

Disposable immunosensor for determination of leptin in serum and breast milk

Scientists in Spain have developed a disposable magnetic bead-based immunosensor to detect the hormone leptin. Leptin helps regulate food intake and is thought to play a role in obesity. This new sensor is very sensitive with a lower limit of detection than current immunoassays. The sensor ... more

Characterisation of mercury-binding protein

A 2D-HPLC-UV-ICP-MS system has been developed by scientists in China for the separation and recognition of mercury-binding proteins in human plasma. Environmental mercury can come from both natural and anthropogenic sources and then be biomagnified through the food chain. Exposure can come ... more

analytica Vietnam 2013 – Platform for innovations

For three days, high-quality laboratory equipment and the latest analysis devices were the focus of the third analytica Vietnam in Ho Chi Minh City. 114 exhibitors from ten countries presented their exhibits to more than 3,400 trade visitors. The content in the program of related events, wh ... more

Analytik Jena announces forecast for financial year 2012/2013

Analytik Jena AG (AJA) expects sales for the current financial year 2012/2013 to exceed EUR 100.0 m for the first time in the Company's history. This was announced today by the manufacturer of analytical instrumentation, life science instruments and optoelectronics in the run-up to its Annu ... more

Reading the human genome

Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have achieved a major advance in understanding how genetic information is transcribed from DNA to RNA by providing the first step-by-step look at the biomolecular machinery that reads ... more

Taking the gamble out of DNA sequencing

Two USC scientists have developed an algorithm that could help make DNA sequencing affordable enough for clinics – and could be useful to researchers of all stripes.Andrew Smith, a computational biologist at the USC Dornsife College of Letters, Arts and Sciences, developed the algorithm alo ... more

High throughput phenotyping of uropathogenic E. coli isolates with Fourier transform infrared spectroscopy

UK scientists have designed a high throughput method to determine the phenotypes of the different Escherichia coli strains that cause urinary tract infections. The method couples bacterial growth requirements to Fourier transform infrared spectroscopy. The majority of urinary tract infectio ... more

Dying Brightly

Programmed cell death, or apoptosis, occurs tens of millions of times every day in every human body. Researchers in South Korea have devised an easy method to detect apoptotic cells by fluorescence, as they report in Chemistry—An Asian Journal. Their method makes it easier to detect imprope ... more

Mobile material analysis by NIR spectrometer in sugar cube format

The Fraunhofer Institute for Photonic Microsystems IPMS will be presenting an extremely miniaturized near-infrared spectrometerThis device enables analysis of gaseous, liquid and solid materials immediately on site instead of taking samples for lab analysis. The optical bench is smaller tha ... more

All news on bioanalytics

An end to chasing structures that were never there

Research describes a rapid computational method for identifying incorrect molecular structures that have been mistakenly determined using misassigned NMR signals. Ariel Sarotti, a scientist in Argentina, has developed a tool that combines calculated and experimental 13C NMR data to flag up ... more

A well-matched couple

Photoacoustic (PA) imaging is a method to visualize structures with optical contrast in biological tissue. Despite the strong optical scattering in tissue, high resolution images in the visible and near infrared spectral range can be obtained. The method is based on sound waves which are ge ... more

ZEISS to acquire Xradia to complement its microscopy business

ZEISS announced the planned acquisition of the US-based Xradia, Inc. Xradia is an medium-size company providing innovative 3D X-ray microscopes for industrial and academic research applications. The closing of the transaction is subject to the fulfillment of customary closing conditions inc ... more

Frost & Sullivan anticipates large-scale switch to digital pathology systems

Evolving technologies and market forces reveal that digital pathology is poised to radically affect the daily workflow and activities of pathologists and diagnostic laboratories. Attracted by the prospect of improved connectivity and reduced overall healthcare costs, most laboratories are a ... more

Nanotechnology helps track and improve drug action in pancreatic cancer

UK and Australian scientists have been able to show ways in which we can markedly improve drug targeting of solid tumours, using tiny 'biosensors' along with new advanced imaging techniques. In real time and in three dimensions, these technologies can show us how cancers spread and how acti ... more

Luminous bacterial proteins detect chemicals in water

While residual medications don’t belong in the water, trace metals from industrial process waters handled by the recycling industry are, in contrast, valuable resources. Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have developed a simple color sensor principle which facili ... more

A safe route to a needle-free diabetes sensor

Research reports a new metal oxide semi-conductor (MOS)-based breath test for diabetes that can be produced safely and at a low cost, without employing flame spray pyrolysis. Flame spray pyrolysis is the usual method for making MOS-based sensors, but it can involve unsafe processing procedu ... more

Mechanically-driven portable device that extracts nucleic acids from blood to measure HIV viral load

Research describes the development of a portable device that can extract HIV viral RNA from whole human blood to produce a purified and thermally-stable sample without the use of electric power. The technology has the potential to enable accurate monitoring of patient response to HIV treatm ... more

Volcano pollution could lead to Parkinson’s misdiagnosis

Research suggests that the effects of pollution from eruptions from Mount Etna could be leading to misdiagnosis of Parkinson’s disease in the surrounding area. Scientists in Italy used X-ray photoelectron spectroscopy (XPS) for the first time to investigate the chemical composition of the s ... more

New screening technique paves the way for protein drugs from bacteria

A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield. Using the bacterium E. coli, researchers from the University's Faculty of Engineering showed it was possible to vastly increase the efficiency of the cel ... more

All news on biotechnology

A spoonful of sugar helps control fluid flow

Research describes a simple, instrument-free method for controlling fluid flow in paper microfluidic devices by applying sugar solutions at different concentrations to slow down the flow of liquid. Many diagnostic assays require the addition of several solutions and washing steps in a preci ... more

Analytik Jena to develop products for sepsis diagnostics

Analytik Jena has acquired all of the assets of the insolvent company SIRS-Lab GmbH as part of an asset deal. SIRS-Lab, a company that develops molecular diagnostics methods and testing systems for life-threatening infections like sepsis, had filed for insolvency in December 2012. Analytik ... more

Quinten identifies a combination of two synergistic markers that predicts a favorable response to treatment in breast cancer

Quinten announced the identification of two discriminating biological marker candidates which are indicative of a favorable response to treatment in women suffering from triple-negative breast cancer (TNBC). In the sub-group with both markers in combination, 86 per cent of women responded t ... more

Oslo study: 3D mammography in combination with 2D breast exam finds significantly more cancers than 2D breast exam alone

Hologic, Inc.announced that a new study published in Radiology, found that the addition of three dimensional mammography screening technology to a 2D breast screening exam significantly increased cancer detection while reducing the number of false positives. The study, "Comparison of Digita ... more

Diagnostics Company SIRS-Lab insolvent

SIRS-Lab requested the opening of insolvency proceedings. The company, founded ten years ago, develops molecular diagnostic technologies for life-threatening infections as sepsis, also known as blood poisoning. Sepsis claims 250.000 victims per year in the USA alone. Therefore SIRS-Lab has ... more

Lab21 announces sale of South Carolina Operations

Lab21 Limited announced the sale of its laboratory operations based in South Carolina to Reedy Acquisitions Corp, an entity formed by the existing local management and South Carolina based investors. In addition to an immediate cash benefit for Lab21 Ltd, the sale will remove a loss-making ... more

Method developed by VTT targets diagnosis of early Alzheimer’s disease

A software tool called PredictAD developed by VTT Technical Research Centre of Finland promises to enable earlier diagnosis of the disease on the basis of patient measurements and large databases. Alzheimer’s disease currently takes on average 20 months to diagnose in Europe. VTT has shown ... more

Researchers discover gender-based differences in Alzheimer's disease

All patients with Alzheimer's disease (AD) lose brain cells, which leads to a shrinking, or atrophy, of the brain. But the pattern of gray matter loss is significantly different in men and women, according to a study presented at the annual meeting of the Radiological Society of North Ameri ... more

Rapid Detection of Malaria

An estimated 220 million people become infected with malaria each year. The disease is often lethal – particularly in tropical developing countries with insufficient health care services. The infected suffer from a high fever. As this is also the case with other germs, however, it is import ... more

Thermo Fisher Scientific Opens New Manufacturing Facility in China

Thermo Fisher Scientific Inc. announced the official opening of its new facility in Suzhou, China, for the manufacturing of life sciences consumables and equipment. The facility expands the company’s global manufacturing footprint and establishes local production capabilities to meet increa ... more

All news on diagnostics

ZEISS to acquire Xradia to complement its microscopy business

ZEISS announced the planned acquisition of the US-based Xradia, Inc. Xradia is an medium-size company providing innovative 3D X-ray microscopes for industrial and academic research applications. The closing of the transaction is subject to the fulfillment of customary closing conditions inc ... more

Mechanically-driven portable device that extracts nucleic acids from blood to measure HIV viral load

Research describes the development of a portable device that can extract HIV viral RNA from whole human blood to produce a purified and thermally-stable sample without the use of electric power. The technology has the potential to enable accurate monitoring of patient response to HIV treatm ... more

Analytik Jena receives major order for diagnostic detection systems from Pakistan

Analytik Jena AG has received a large order through its Leipzig-based subsidiary AJ Roboscreen GmbH requiring the delivery of systems for the preparation of samples and the detection of various viruses to eleven clinical laboratories in Pakistan. AJ Roboscreen GmbH secured the invitation to ... more

Frost & Sullivan: Opportunities for electronics manufacturing services in medical industry increasing

Original equipment manufacturers (OEMs) are increasingly turning to electronics manufacturing service (EMS) providers to better handle the escalating volumes of electronic content in the medical industry. With opportunities for high-level product assembly and complete build projects expecte ... more

ZEISS presents half-year financial figures

During the first six months of fiscal year 2012/13 the business trend in the ZEISS Group was marked by the difficult conditions experienced in some markets. Nevertheless, the Group concluded the first half of the year (ended 31 March) with revenue totaling EUR 1.978 billion (first six month ... more

Analytik Jena to develop products for sepsis diagnostics

Analytik Jena has acquired all of the assets of the insolvent company SIRS-Lab GmbH as part of an asset deal. SIRS-Lab, a company that develops molecular diagnostics methods and testing systems for life-threatening infections like sepsis, had filed for insolvency in December 2012. Analytik ... more

Core facilities: Widening access to research instrumentation

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has approved funding for ten additional core facilities to make existing research instrumentation more easily and efficiently accessible to researchers. This decision was made by the DFG's Joint Committee. The projects wi ... more

analytica Vietnam 2013 – Platform for innovations

For three days, high-quality laboratory equipment and the latest analysis devices were the focus of the third analytica Vietnam in Ho Chi Minh City. 114 exhibitors from ten countries presented their exhibits to more than 3,400 trade visitors. The content in the program of related events, wh ... more

Analytik Jena announces forecast for financial year 2012/2013

Analytik Jena AG (AJA) expects sales for the current financial year 2012/2013 to exceed EUR 100.0 m for the first time in the Company's history. This was announced today by the manufacturer of analytical instrumentation, life science instruments and optoelectronics in the run-up to its Annu ... more

Thermo Fisher Scientific to Acquire Life Technologies Corporation

Thermo Fisher Scientific and Life Technologies Corporation have signed a definitive agreement under which Thermo Fisher will acquire Life Technologies for $76.00 in cash per fully diluted common share, or approximately $13.6 billion, plus the assumption of net debt at close ($2.2 billion as ... more

All news on lab technology

PRAC recommends restricting the use of codeine when used for pain relief in children

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended a series of measures to address safety concerns with codeine-containing medicines when used for the management of pain in children. This follows the PRAC’s review of reports of children who de ... more

PRAC recommends the same cardiovascular precautions for diclofenac as for selective COX-2 inhibitors

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that the effects of the painkiller diclofenac on the heart and circulation when given systemically (by means such as capsules, tablets or injections) are similar to those of selective COX-2 inhi ... more

Resolutions of the Annual General Meeting of Evotec

Shareholders of Evotec AG approved the actions of the members of the Management Board and the Supervisory Board for the fiscal year 2012 at the Annual General Meeting. The Chief Executive Officer of Evotec AG, Dr Werner Lanthaler, presented the Company's performance for the year 2012 and pr ... more

New sickle cell anemia therapy advances to Phase II clinical trials

Seeking to improve the lives of sickle cell anemia sufferers around the world, researchers from the La Jolla Institute for Allergy and Immunology, the Dana-Farber/Children's Hospital Cancer Center in Boston and the BloodCenter of Wisconsin in Milwaukee and others are preparing to launch Pha ... more

DHL launches industry-changing temperature controlled Life Sciences air freight service

DHL Global Forwarding launches DHL Thermonet, a new air freight product tailored to the Life Sciences and Healthcare sector. This global service is a new addition to DHL’s network of Life Sciences and Healthcare facilities and offers customers a transparent and a regulatory compliant platfo ... more

European Medicines Agency and EUnetHTA review progress of their cooperation

The European Medicines Agency (EMA) and EUnetHTA, the European network for Health Technology Assessment (HTA), met to review the progress of their cooperation in London on 14 May 2013. This was the sixth meeting since the start of their collaboration in 2010. The focus of this meeting was o ... more

New screening technique paves the way for protein drugs from bacteria

A cheaper, more efficient technique for developing complex protein drugs from bacteria has been developed at the University of Sheffield. Using the bacterium E. coli, researchers from the University's Faculty of Engineering showed it was possible to vastly increase the efficiency of the cel ... more

EMA recommends approval of pomalidomide for the treatment of multiple myeloma

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended marketing authorisation for Pomalidomide Celgene (pomalidomide) to treat patients with multiple myeloma. Multiple myeloma is a rare and incurable cancer of the bone marrow that primarily af ... more

Oral almitrine to be withdrawn by EU Member States

The Co-ordination Group for Mutual Recognition and Decentralised Procedures – Human (CMDh), a medicines regulatory body representing the EU Member States, has endorsed the recommendation by the EMA’s Pharmacovigilance Risk Assessment Committee (PRAC), that permission to market oral medicine ... more

Releasing reactive oxygen from nanoparticles

Research describes the synthesis of nanoparticles that release singlet oxygen when a laser beam is shone on them. The nanoparticles could improve the effectiveness of photodynamic therapy, a treatment for some cancers.  Photodynamic therapy is based on the combination of oxygen, light and p ... more

All news on pharma

PRAC recommends restricting the use of codeine when used for pain relief in children

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has recommended a series of measures to address safety concerns with codeine-containing medicines when used for the management of pain in children. This follows the PRAC’s review of reports of children who de ... more

Psychiatric disorders linked to a protein involved in the formation of long-term memories

Researchers have discovered a pathway by which the brain controls a molecule critical to forming long-term memories and connected with bipolar disorder and schizophrenia. The discovery was made by a team of scientists led by Alexei Morozov, an assistant professor at the Virginia Tech Carili ... more

Study finds racial and ethnic disparities in usage of specialty services for children with autism

A study from investigators at MassGeneral Hospital for Children (MGHfC) found that African-American or Hispanic children diagnosed with autism were significantly less likely than white children to have received subspecialty care or procedures related to conditions that often accompany autis ... more

Presentation of the 2013 Eppendorf Award for Young European Investigators

The British scientist Ben Lehner, Ph.D., ICREA Research Professor, EMBL-CRG Systems Biology Unit at the Centre de Regulació Genòmica, in Barcelona, Spain, has won the 2013 Eppendorf Young Investigator Award. Lehner, born 1978, receives the Eppendorf Award for his discoveries concerning the ... more

PRAC recommends the same cardiovascular precautions for diclofenac as for selective COX-2 inhibitors

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) has concluded that the effects of the painkiller diclofenac on the heart and circulation when given systemically (by means such as capsules, tablets or injections) are similar to those of selective COX-2 inhi ... more

Be gone, bacteria

Staph infections in hospitals are a serious concern, so much so that the term Methicillin-resistant Staphylococcus aureus (MRSA) is as commonly known as MRI. Far less known is that in many of these cases, patients are infecting themselves. In heart surgeries and knee and joint-replacement p ... more

Developmental protein plays role in spread of cancer

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Dieg ... more

Using math to kill cancer cells

Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique predicts how different treatments and genetic modifications mi ... more

First major study of suicide motivations to advance prevention

A University of British Columbia study sheds important new light on why people attempt suicide and provides the first scientifically tested measure for evaluating the motivations for suicide. Published in the official journal of the American Association of Suicidology, the work gives doctor ... more

Obesity increases the risk of preterm delivery

The risk of preterm delivery increases with maternal overweight and obesity, according to a new Swedish study. Women with the highest Body Mass Index (BMI) also had the highest statistical risk of giving preterm birth – and especially extremely preterm birth. “For the individual woman who i ... more

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