CureVac AG announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance to CureVac on GMP-conforming pharmaceutical manufacturing methods for producing RNA, strengthening CureVac’s industry-leading position in GMP manufacturing of in vitro transcribed RNA.
CureVac is ... more
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP ... more
A newly designed three-part molecule could be the one answer patients with a certain form of breast cancer are looking for, scientists report.
This chimera, created by a team at the Georgia Cancer Center, has the ability to simultaneously decrease the expression of three growth factors that ... more
An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health (NIH), has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclero ... more
Potential drug target is identified
Apicomplexa form one of the largest and most diverse groups of obligate intracellular parasites, capable of infecting almost every kind of animal. It is estimated that between 1.2 and 10 million species exist, but only about 5,000-6,000 have been identified to date. These include Plasmodium ... more
Funding used for production capacity and commercialization of novel products
Oxford Nanopore Technologies Ltd has raised £100M ($140M) in new investment. Funds were raised from global investors including GIC (Singapore), China Construction Bank International (CCBI, China), Hostplus (Australia), and existing investors.
The funds will be used to support the Company’s ... more
Just as diamond ring is needed in marriage, NuA4/Tip60, a complex with diamond ring architecture, is required for regulatory and repairing processes. Prof. CAI Gang and Prof. Jacques Côté's team reports the 4.7 Å structure of the yeast NuA4/TIP60 complex, which elucidates the detailed archi ... more
First steps of photosynthesis uncovered
Photosynthesis has driven life on this planet for more than 3 billion years -- first in bacteria, then in plants -- but we don't know exactly how it works.
Now, a University of Michigan biophysicist and her group have been able to image the moment a photon sparks the first energy conversion ... more
Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a cell determine what that cell can do. Among the multiple elements that are involved in the precise regulation of gene expression are enhancers, which are short region of DNA that can b ... more
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of living zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of dis ... more