Scientists at the University of Copenhagen, led by the Spanish Professor Guillermo Montoya, are investigating the molecular features of different molecular scissors of the CRISPR-Cas system to shed light on the so-called 'Swiss-army knives' of genome editing. Montoya's research group has vi ... more
Lipid, also known as fat, is an optimal energy source and an important cell component. Much is required for the rapid and uncontrolled growth of cancer cells. Researchers from the Biozentrum of the University of Basel and from the University of Geneva have now discovered that the protein mT ... more
Urgent warning from FDA
Gene therapy is the administration of genetic material to modify or manipulate the expression of a gene product or to alter the biological properties of living cells for therapeutic use. Gene therapies offer the potential to treat diseases or conditions for which no or few treatments exist. ... more
It took several years, but a research team headed by Professor Jens Nielsen at Chalmers University of Technology has finally succeeded in mapping out the complex metabolism of yeast cells. The breakthrough, recently published in an article in Nature Communications, means a huge step forward ... more
How do cells move in a certain direction in the body -- go to a wound site and repair it, for example, or hunt down infectious bacteria and kill it?
Two new studies from the Marine Biological Laboratory (MBL) show how cells respond to internal forces when they orient, gain traction, and mig ... more
Chaperones help folding of other proteins
Just like an acrobatic duo, some proteins lend each other stability. Researchers at the Biozentrum of the University of Basel have discovered that the protein “Trigger factor” recognizes a partner by instable, flexible domains, to then together form a stable protein duo.
Misfolded proteins ... more
In 2006, Caltech's Paul Rothemund (BS '94)—now research professor of bioengineering, computing and mathematical sciences, and computation and neural systems—developed a method to fold a long strand of DNA into a prescribed shape. The technique, dubbed DNA origami, enabled scientists to crea ... more
Microbiologists led by Derek Lovley at the University of Massachusetts Amherst, who is internationally known for having discovered electrically conducting microfilaments or "nanowires" in the bacterium Geobacter, announce in a new paper this month that they have discovered the unexpected st ... more
A research team in the Department of Electrical and Electronic Information Engineering and the Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) at Toyohashi University of Technology has developed an ultrastretchable bioprobe using Kirigami designs. The Kirigami-based biopr ... more
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain ... more