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Major Histocompatibility Complex Genotyping with Massively Parallel Pyrosequencing


Macaques provide essential preclinical models for infectious disease, vaccine, biodefense, and transplantation research. Unfortunately, they also have the most complex MHC genetics of any primate species described to date, and existing methods for MH


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Array Capture-mediated Resequencing Leads to the Discovery of Four Novel Mutations in the Mouse


By using array-based sequence capture and pyrosequencing to sequence an allelic series from the classically defined Kit locus (~200 kb) from each of five noncomplementing Kit mutants (one known allele and four unknown alleles), D'Ascenzo and co-worke


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New Products for Cell Culture Analysis from Roche Innovatis


The Roche Innovats product line is now available from Roche Applied Sciences. Below is a short introduction to three Roche Innovatis product lines designed for the complete analysis of cell cultures, from the simple determination of cell concentratio


Characterizing Environments: Recent Discoveries Enabled by Metagenomic Analysis with the Genome Sequencer FLX System


Metagenomics is the study of genomic content in a complex mixture of microorganisms. The two primary goals of this approach are to characterize the organisms present in a sample and identify what roles each organism has within a specific environment.


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