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27-Jul-2017 - Attaching curcumin, a component of the common spice turmeric, to nanoparticles can be used to target and destroy treatment-resistant neuroblastoma tumor cells, according to a new study. The study, conducted in partnership by researchers at Nemours Children's Hospital and the University of Central ...
30-Mar-2017 - To survive in human cells, chlamydiae have a lot of tricks in store. Researchers of the University of Würzburg have now discovered that the bacterial pathogens also manipulate the cells' energy suppliers in the process. When Chlamydia trachomatis infects a human cell, it faces a huge challenge: ...
22-Mar-2017 - MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs. By tethering hundreds of tiny particles to the surfaces of tumor cells in the presence of a mechanical force, the ...
08-Mar-2017 - Regeneration is an inherent property of life. However, the potential to regenerate differs across species: while fish and amphibians can re-grow appendages such as limbs, tails, and fins, mammals, including humans, cannot restore injured organs to their original shape and function. Therefore, ...
03-Jan-2017 - A new active pharmaceutical ingredient may help against severe forms of testicular cancer, which only respond inadequately to other therapies. In mice, the substance kills degenerated cells and allows testicular tumors to shrink. Researchers at the University of Bonn were able to demonstrate this ...
28-Nov-2016 - How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. "Our finding is part of a growing interest in studying the metabolic function of cancer," says Ubaldo ...
11-Jul-2016 - When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don't just disappear. They wind up in the blood stream, where degraded bits and pieces can be extracted. This cell-free DNA (cfDNA) is degraded due to its exposure to enzymes in the blood but ...
Isoketal-modified proteins as a potential therapeutic target of pulmonary fibrosis
08-Jun-2016 - Isoketals (IsoKs) – highly reactive compounds formed when membrane lipids are attacked by free radicals – are emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, the identity of IsoK-modified proteins and whether isoketal generation is ...
20-May-2016 - Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer in Switzerland. Despite intensive chemotherapy, one fifth of the patients suffer a relapse, which usually goes hand in hand with a poor prognosis. Researchers from the University of Zurich and the Children’s Hospital ...
This is due to unequal distribution of a ‘killer factor’ by the mother cell
14-Dec-2015 - Programmed cell death – also known as apoptosis – is universal among higher organisms, and is a tightly regulated process that results in the disposal of damaged or unwanted cells. The latter variant is particularly important in the course of embryonic development, during which many more cells ...
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