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26-Oct-2015 - New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections. Now, new ...
Tübingen researchers have studied the formation of membrane pores that are critical to start the apoptosis program
18-Aug-2015 - When cells age or suffer damage, they are able to actively bring about their own pre-programmed death known as apoptosis. A desensitization of this process determines the change from a normal cell into a cancer cell. On the other hand, an over-functioning of apoptosis is associated to the onset ...
08-Apr-2014 - Researchers from the University of Pittsburgh Cancer Institute (UPCI), a partner with UPMC CancerCenter, have found that an agent that inhibits mitochondrial division can overcome tumor cell resistance to a commonly used cancer drug, and that the combination of the two induces rapid and ...
02-Apr-2014 - A new research discovery published in the issue of the Journal of Leukocyte Biology may open the door to new therapies that help treat immune disorders or curb runaway inflammation. Specifically, scientists have discovered a molecule that can induce cell death (apoptosis) in a key type of immune ...
10-Dec-2013 - A new study conducted by scientists from the Dana-Farber Cancer Institute at Harvard Medical School and Karolinska Institutet in Sweden presents very promising results for the treatment of the cancer form multiple myeloma. The drug candidate used in the research has been developed by scientists ...
23-Oct-2013 - Researchers at the University of California, San Diego School of Medicine have discovered a way to effectively deliver staurosporine (STS), a powerful anti-cancer compound that has vexed researchers for more than 30 years due to its instability in the blood and toxic nature in both healthy and ...
12-Aug-2013 - New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival. Scientists from Cincinnati Children's Hospital Medical Center report ...
26-Apr-2013 - Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at the University of Pittsburgh School of Medicine. In a report published ...
23-Apr-2013 - The protective effect of inducing controlled hypothermia following sudden cardiac arrest will now be investigated in detail. The goal of the scientific work is to judge whether this type of cryotherapy can be improved when using parallel simultaneous invasive resuscitation procedures. ...
Fluorescence lights up cells programmed to die
28-Jan-2013 - Programmed cell death, or apoptosis, occurs tens of millions of times every day in every human body. Researchers in South Korea have devised an easy method to detect apoptotic cells by fluorescence, as they report in Chemistry—An Asian Journal. Their method makes it easier to detect improper ...
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