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'Relaxed' T cells critical to immune response

Researchers model how cells handle invaders, ignore imposters

18-Jun-2020

Like finding that needle in the haystack every time, your T cells manage what seems like an improbable task: quickly finding a few invaders among the many imposters in your body to trigger its immune response. T cells have to react fast and do so nearly perfectly to protect people from diseases. ...

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Chemists show it's hip to be square

Their synthetic azetidines could help simplify drug design for neurological diseases

13-Aug-2019

Rice University chemists want to make a point: Nitrogen atoms are for squares. The nitrogens are the point. The squares are the frames that carry them. These molecules are called azetidines, and they can be used as building blocks in drug design. The Rice lab of chemist László Kürti introduced ...

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Organ bioprinting gets a breath of fresh air

Bioengineers clear major hurdle on path to 3D printing replacement organs

06-May-2019

Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and ...

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Bacteria bide their time when antibiotics attack

Rice University study suggests strategies for better dosage to fight infections

26-Mar-2019

If an antibiotic doesn't kill all the bacteria that infects a patient, the surviving bugs may be particularly adept at timing their resurgence. Theoretical scientists at Rice University have proposed a better way to understand how to prescribe antibiotics to kill every last bacterium or at least ...

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Shaping light lets 2D microscopes capture 4D data

Invention adds new dimension to fluorescent microscopy

20-Feb-2019

Rice University researchers have added a new dimension to their breakthrough technique that expands the capabilities of standard laboratory microscopes. Two years ago, the Rice lab of chemist Christy Landes introduced super temporal resolution microscopy, a technique that allowed researchers to ...

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Nitrogen gets in the fast lane for chemical synthesis

Chemists discover way to simplify synthesis of valuable precursor for drugs, other compounds

12-Feb-2019

Rice University scientists have given organic chemists a boost with their latest discovery of a one-step method to add nitrogen to compounds for drugs, pesticides, fertilizers and other products. Rice synthetic organic chemist László Kürti said the method is a major step forward as it quickens ...

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Moths and magnets could save lives

Experimental therapy could repair mutations that cause genetic diseases

15-Nov-2018

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis. Rice University bioengineer Gang Bao has combined magnetic nanoparticles with a viral container drawn ...

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A method to quickly enhance immune-system proteins

07-Nov-2018

Rice University scientists have found a simple method to attach drugs or other substances to antibodies, the powerful proteins that are central to the body's immune system. The Rice lab of bioengineer Han Xiao developed a technique called pClick, which uses a cross-linker that snaps to a specific ...

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Iron outperforms gadolinium as MRI contrast agent

24-Aug-2018

Rice University nanoscientists have demonstrated a method for loading iron inside nanoparticles to create MRI contrast agents that outperform gadolinium chelates, the mainstay contrast agent that is facing increased scrutiny due to potential safety concerns. "The possibility of eliminating ...

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A new way to target flu virus

26-Jul-2018

There's a hitch in the swing of a protein that delivers the flu virus. Rice University and Baylor College of Medicine researchers believe this mechanism may be a useful target to stop the virus from infecting cells. The Rice-Baylor team led by biophysicist José Onuchic and biochemists Jianpeng Ma ...

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