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The relationship of proteins

Researchers have for the first time uncovered the proteome of 100 organisms from all domains of life

19-Jun-2020

Proteins control life as one of the most important biomolecules - as enzymes, receptors, signal or structural building blocks. Researchers at the Max Planck Institute (MPI) of Biochemistry have for the first time uncovered the proteomes of 100 different organisms. The selected specimens come from ...

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Biological machine produces its own building blocks

Researchers have for the first time developed a genome the size of a minimal cell that can copy itself

18-Feb-2020

The field of synthetic biology does not only observe and describe processes of life but also mimics them. A key characteristic of life is the ability to ability for replication, which means the maintenance of a chemical system. Scientists at the Max Planck Institute of Biochemistry in Martinsried ...

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In the right place at the right time

Scientists decipher the activation chain of protein degradation

17-Feb-2020

Proteins are molecular work horses in the cell that perform specific tasks, but it is essential that the timing of protein activities is exquisitely controlled. When proteins have fulfilled their tasks, degradation of these proteins will end processes that are unneeded or detrimental. To control ...

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The recipe for making a fruit fly

Scientists use mass spectrometry to determine the absolute copy number of nuclear proteins and histone marks

21-Oct-2019

Currently, most if not all of the proteins that are required for constructing a multicellular organism are known. However, it is largely unclear how many copies of each protein species are present and needed to permit an animal to develop into a complete organism. Researchers at the Max Planck ...

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Lasker Award 2019 for the invention of Herceptin

11-Sep-2019

Herceptin was the first monoclonal antibody that blocks a cancer causing protein. For the invention of Herceptin and the development of a life-saving therapy for women with breast cancer, three researchers are now receiving the Lasker~DeBakey Clinical Medical Research Award: Axel Ullrich, ...

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Breakthrough Prize 2020 for biochemist Hartl and geneticist Horwich

09-Sep-2019

F.-Ulrich Hartl, Director at the Max Planck Institute of Biochemistry in Martinsried, is awarded the Breakthrough Prize in Life Sciences 2020 together with Arthur L. Horwich of Yale School of Medicine/HHMI. They are honored for discovering functions of molecular chaperones in mediating protein ...

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Screening proteins to expose early signs of illness

Matthias Mann named European Inventor Award 2019 finalist

08-May-2019

The European Patent Office (EPO) announces that German physicist, biochemist and bioinformatician Matthias Mann has been nominated for the European Inventor Award 2019 for developing techniques to screen proteins in bulk for the early detection of disease. Named as one of three finalists in the ...

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Access control for proteins

27-Nov-2018

The trans-Golgi network (TGN) is the central hub for the transport of proteins within and out of cells. As protein transport is essential for cell biology, the cell closely regulates which proteins are packaged and transported in vesicles. However, the process by which non-signal-carrying ...

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Decoding the structure of huntingtin

Determining the three dimensional structure of the protein could help to develop new treatments of Huntington's disease

23-Feb-2018

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein. With the help of cryo-electron microscopy researchers from the Max Planck Institute of Biochemistry in Martinsried and Ulm University have now ...

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The future of crop engineering

Scientists want to increase the efficiency of photosynthesis

11-Dec-2017

Photosynthesis is the process underlying all plant growth. Scientists aim to boost photosynthesis to meet the increasing global demand for food by engineering its key enzyme Rubisco. Now, researchers at the Max Planck Institute of Biochemistry have succeeded in producing functional plant Rubisco ...

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