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Determining the three dimensional structure of the protein could help to develop new treatments of Huntington's disease
23-Feb-2018 - Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein. With the help of cryo-electron microscopy researchers from the Max Planck Institute of Biochemistry in Martinsried and Ulm University have now ...
Scientists want to increase the efficiency of photosynthesis
11-Dec-2017 - Photosynthesis is the process underlying all plant growth. Scientists aim to boost photosynthesis to meet the increasing global demand for food by engineering its key enzyme Rubisco. Now, researchers at the Max Planck Institute of Biochemistry have succeeded in producing functional plant Rubisco ...
Quality control in the mitochondria
01-Nov-2017 - A common feature of neurodegenerative diseases such as Alzheimer's, Parkinson's or Huntington's disease are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions. Scientists report that, even in normal cells, aberrant aggregation-prone proteins are ...
26-Sep-2017 - Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. However, Rubisco performs this reaction slowly and can also have unwanted reactions with oxygen. Algae have figured out a clever way to increase the efficiency of carbon ...
21-Sep-2017 - Proteins are often considered as molecular machines. To understand how they work, it is not enough to visualize the involved proteins under the microscope. Wherever machines are at work mechanical forces occur, which in turn influence biological processes. These extremely small intracellular ...
“Macrophages are real chatterboxes”
02-May-2017 - Facebook, Instagram, Twitter – nowadays, good social networking and communication is more important than ever. The immune system also resembles a large social network, as shown by Felix Meissner and his team in the Experimental System Immunology Research Group at the Max Planck Institute of ...
21-Mar-2017 - Although all cells in an organism contain the same genes, only some of the genes are activated in a given cells and others remain inactive. Genes coil around histone proteins in the form of DNA threads. If a gene has to remain inactive, its histones are marked by the PRC2 enzyme so that this gene ...
20-Mar-2017 - A team of Dutch and German researchers under the leadership of Albert Heck and Friedrich Förster has discovered the operation of one of the oldest biological clocks in the world, which is crucial for life on earth as we know it. The researcher from the Max Planck Institute of Biochemistry and the ...
Chromosome segregation in meiosis
17-Jan-2017 - Once together, never apart – isn’t that how the saying goes? Not so in meiosis, the special type of cell division in which gametes, sperm and egg cells are formed. At the start of meiosis the ring-shaped protein complex, referred to as cohesin, is the string that ties the chromosome strands ...
29-Jun-2016 - The degradation of proteins and the re-use of their basic building blocks is a process that is a matter of survival in cells. Researchers at the Max-Planck-Institute for Biochemistry present a detailed structure of the human protein recycling machine, the so-called 26S proteasome, in near-atomic ...
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