Hawaii Biotech Inc reports favourable phase 1 interim results to treat West Nile Virus

27-Feb-2009 - Australia

Hawaii Biotech, Inc., announced successful Phase 1 clinical trial results of its West Nile Virus vaccine in healthy volunteers. Hawaii Biotech is developing a West Nile recombinant sub-unit vaccine to induce protective immunity in recipients of the vaccine.

The results demonstrated a favourable safety profile in 24 subjects across four cohorts. The Phase 1 study was designed as an ascending dose study to assess the safety of Hawaii Biotech’s West Nile Virus vaccine among healthy adult volunteers who had not been exposed to the West Nile or similar virus. The study also examined antibody development to the vaccine. The overall profile was favourable with no serious adverse events. Based on these results, Hawaii Biotech is preparing to proceed with additional safety studies in adults, as well as ultimately expanding studies into elderly, juvenile and immune-compromised populations.

“We are extremely pleased with the safety results of our West Nile Virus vaccine Phase 1 study and are encouraged by the presence of neutralizing antibodies in all individuals receiving the formulated vaccine,” notes Chief Executive Officer and President Dr. Elliot Parks. “Additionally, these results demonstrate the robustness of our protein production platform for the development of additional sub-unit vaccines in our product pipeline,” Parks states.

Other news from the department research and development

Most read news

More news from our other portals

Fighting cancer: latest developments and advances

See the theme worlds for related content

Topic world Antibodies

Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous

View topic world

Topic world Antibodies

Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous