Viragen Reports Achievement of Key Avian Transgenics Milestone
Anti-Cancer Antibody Expressed In Chicken Eggs Promises to Revolutionize Drug Production
The therapeutic protein successfully expressed, using Oxford BioMedica's LentiVector® gene delivery system in this proprietary avian system, is a novel structure of an antibody in Viragen's product portfolio being designed to target malignant melanoma. Three other protein-drug candidates are included in ongoing avian expression studies to demonstrate the breadth of its capabilities, including two commercially marketed products, each of which realizes more than $2 billion in annual sales.
Viragen and Roslin confirmed qualitative and quantitative detection, and recovery of humanized antibody from the eggs. The analysis indicates that the expression levels measured are significantly higher than any previously published results for a therapeutic protein produced from an avian transgenic line.
The Project's scientific leader, Roslin Senior Scientist, Dr. Helen Sang, Ph.D., lauded the breakthrough, "We have long believed that this joint effort would develop an avian system capable of efficiently and economically producing human biopharmaceuticals, and with this major milestone achievement, I am even more convinced that we are developing an elite manufacturing platform that should emerge as a method of choice for many products."
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Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.
Topic world biopharmaceutical manufacturing
Biopharmaceutical production plays a crucial role in the development and manufacture of biologics, which are essential for the treatment of various serious diseases. Various key technologies and processes of the modern biopharmaceutical industry are used, such as cell cultures, fermentation processes and the purification of biological substances, which are necessary for the production of vaccines, monoclonal antibodies and other biological drugs.