Astex granted patent covering for the drug metabolising human cytochrome P450 3A4

26-Jan-2005

Astex Technology announced issuance of patent GB23957181 covering the use of the crystal structure of human cytochrome P450 3A4, the most important drug metabolising enzyme in man. It is estimated that as many as 50% of all known drugs interact with this form of cytochrome P450 and as such it represents a major problem for drug developers.

Astex has been actively involved in human cytochrome P450 research since the company's formation and Astex scientists were the first group to successfully solve the crystal structures of human cytochromes P450, 3A4 and 2C92.

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