Agilent Technologies and DiagnoSwiss to develop new technology for high-performance proteomics analysis
"Biological samples often contain up to 30,000 different proteins," said Gerard Rozing, Ph.D., a senior scientist at Agilent. "In order to allow researchers to focus on the few critical proteins involved in a specific disease, simple and fast 'filtering' procedures are required. We are confident that Off-Gel electrophoresis will develop into an essential, indispensable tool for proteomics research."
Off-Gel electrophoresis enables the micro-scale separation of proteins and peptides in complex mixtures according to their isoelectric points, grouping them by their common electrical properties. In contrast to conventional gel electrophoresis, the proteins or peptides are recovered in a free solution and in higher concentration than originally applied. The technology is expected to form a valuable solution for high-performance protein fractionation and purification.
"This unique system can be easily combined with other separation methods such as 2-D gel electrophoresis or LC/MS and will eventually allow for automated multi-dimensional separations of complex protein mixtures," said Frédéric Reymond, Ph.D, general manager of DiagnoSwiss. "We look forward to collaborating with Agilent on the commercialization of this technology to create a high- performance, easy-to-use system for protein research."
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