Evolva obtains patent coverage in Russia on EV-077 for use in complications of diabetes
EV-077 prevents isoprostanes and prostanoids, levels of which are elevated in diabetics, from causing inflammatory damage to the vasculature. EV-077 is an oral small molecule that belongs to a new structural class. The mechanism of action of EV-077 means that it can potentially ameliorate or prevent a range of diabetic complications (including loss of kidney function and increased risk of thrombosis). Evolva has recently received clearance to move EV-077 into Phase IIa in this indication. First data are expected by mid-2012.
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