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Serine hydrolase



The serine hydrolase superfamily is one of the largest known enzyme families comprising approximately 1% of the genes in the human genome. This family includes:

Additional recommended knowledge

all of these enzymes share a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine) although variations on this mechanism exist.

See also


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Serine_hydrolase". A list of authors is available in Wikipedia.
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