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Systematic (IUPAC) name
2-[(3-methyl-4-(2,2,2-trifluoroethoxy) pyridin-2-yl) methylsulfinyl] -1H-benzoimidazole
CAS number 103577-45-3
ATC code A02BC03
PubChem 3883
DrugBank APRD00077
Chemical data
Formula C16H14F3N3O2S 
Mol. mass 369.363 g/mol
Pharmacokinetic data
Bioavailability 80% or more
Protein binding 97%
Metabolism Hepatic (CYP3A4- and CYP2C19-mediated)
Half life 1–1.5 hours
Excretion Renal and fecal
Therapeutic considerations
Licence data


Pregnancy cat.

B3(AU) B(US)

Legal status

Prescription only

Routes Oral, IV

Lansoprazole (lan-SOE-pra-zole, INN) is a proton pump inhibitor which prevents the stomach from producing acid. It is manufactured by TAP Pharmaceutical Products.



Lansoprazole is a proton pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPI's available.[citation needed]

Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The mean plasma elimination half-life is 1.5 hours,[1] and the effects of the drug last for over 24 hours after it has been used for 1 day or more.[citation needed]

Prevacid is now manufactured and distributed by Novartis Consumer Health.


Lansoprazole is indicated for:


Side effects

Brand names

  The drug is sold with the following brand names:

  • Aprazol (Turkey)
  • Lansox (Italy)
  • Limpidex (Italy)
  • Prevacid (U.S. and Canada)
  • Takepron (Japan)
  • Zoton (Italy, Australia, UK)
  • Refluxon (Hungary)
  • Duogast (Syria)
  • Lanzap
  • Prosogan
  • Lanton (Israel)
  • Ogast (France)
  • SOLOX (New Zealand)
  • Prosogan FD (Indonesia)

Lansoprazole is also available as a generic drug in Belgium, Colombia, Italy and Mexico.


  1. ^ a b Prevacid Pharmacology, Pharmacokinetics, Studies, Metabolism. (2007). Retrieved on 2007-04-14.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lansoprazole". A list of authors is available in Wikipedia.
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