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Labetalol (Normodyne, Trandate, fixed combination with hydrochlorothiazide: Normozyde) is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance.
It has a particular indication in the treatment of pregnancy-induced hypertension.
Additional recommended knowledge
Labetalol is available in 100, 200, and 300 mg tablets and intravenously (only as Trandate) in 5 mg/ml solution. Adults taking tablets usually start with 100 mg two times a day, with a maximum of 2.4 g/day. In an emergency situation, this may be higher. By IV, the patient is usually started at 2 mg/minute or 20 mg, with a maximum of 300 mg.
Side effects may include:
Should not be used in patients that have asthma, congestive heart failure, any degree of heart blocks, slow heart rates or those in cardiogenic shock
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Labetalol". A list of authors is available in Wikipedia.|