Drug Development

Companies Drug Development

Rigontec GmbH, Germany

Rigontec is a leader in the field of RIG-I-activating RNA therapeutics. Using our proprietary RIG-I agonist platform, we are taking advantage of one of the most important pathways of the innate immune system to develop a novel approach to cancer immunotherapy. Rigontec's proprietary agonists specifi more

Confo Therapeutics, Belgium

Confo Therapeutics is a drug discovery company building a unique pipeline of GPCR targeted therapeutics addressing unmet medical need. The company was founded in 2015 as a spin-off from the Vrije Universiteit Brussel and VIB and capitalizes on the ConfoBody™ technology developed by Prof. Jan Steyae more

Inflamalps SA, Switzerland

Inflamalps is a biopharmaceutical company established in Valais, Switzerland Our mission is ‘’to discover and develop novel medicines to treat inflammation with a focus on chronic inflammatory diseases of the eye and of the skin” Our team comprises experienced pharmaceutical industry and biotechnolo more

News Drug Development

• Merck Licenses Foundational CRISPR Integration Technology to Promega
  

  Merck announced that it has signed a license agreement providing Promega Corp., a global life science manufacturer based in Madison, Wisconsin, USA access to Merck’s foundational CRISPR intellectual property. Promega will use Merck’s CRISPR genome-editing technology to create research products and s more

• Turning 'junk' DNA into gold
  

  Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer. Using state-of-the-art, whole-genome sequencing technologies on prostate tumour samples, Princes more

• Merck Licenses CRISPR Gene-Editing Technology to Evotec
  

  Merck announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for more

Videos Drug Development

White papers Drug Development

• Non-Invasive Real-Time Cell Analytics for Drug Discovery
  

  Roche’s xCELLigence Cardio Instrument is a medium-throughput cell analyzer using impedance recording to monitor cardiac beating and cellular events in real time. The instrument features high resolution detection rate and frequency measurement technol more

• Real-time and Dynamic Monitoring of Virus-mediated Cytopathogenicity
  

  To understand overall infectivity, virus progression and disease onset it is important to perform a detailed examination of cytopathic effects. Depending on the type of viruses and cells, different cytopathic effects might be observed dependent on th more

• Ultra-sensitive Biomarker Quantification in Microsampling Support
  

  Looking for Biomarker quantification in microsampling support? Imperacer® enables target detection in low pg/ml range with lowest sample consumption. more

Publications Drug Development

• Sample-to-sample p-value variability and its implications for multivariate analysis

  Sample-to-sample p-value variability and its implications for multivariate analysisWei Wang; Wilson Wen Bin GohInternational Journal of Bioinformatics Research and Applications, Vol. 14, No. 3 (2018) pp. 235 - 254Statistical feature selection is used for identification of relevant genes from biolog more

• Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa

  Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa Viruses doi: 10.3390/v10070345 Authors: Tobi E. Nagel The antimicrobial resistance (AMR) crisis and HIV/AIDS epidemic ex more

• Pharmaceuticals, Vol. 11, Pages 64: Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder

  Pharmaceuticals, Vol. 11, Pages 64: Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder Pharmaceuticals doi: 10.3390/ph11030064 Authors: Adwitia Dey Pamela A. Hankey Giblin Over 350 million individuals suffer from depression, a more