Drug Development

Companies Drug Development

Confo Therapeutics, Belgium

Confo Therapeutics is a drug discovery company building a unique pipeline of GPCR targeted therapeutics addressing unmet medical need. The company was founded in 2015 as a spin-off from the Vrije Universiteit Brussel and VIB and capitalizes on the ConfoBody™ technology developed by Prof. Jan Steyae more

Inflamalps SA, Switzerland

Inflamalps is a biopharmaceutical company established in Valais, Switzerland Our mission is ‘’to discover and develop novel medicines to treat inflammation with a focus on chronic inflammatory diseases of the eye and of the skin” Our team comprises experienced pharmaceutical industry and biotechnolo more

Rigontec GmbH, Germany

Rigontec is a leader in the field of RIG-I-activating RNA therapeutics. Using our proprietary RIG-I agonist platform, we are taking advantage of one of the most important pathways of the innate immune system to develop a novel approach to cancer immunotherapy. Rigontec's proprietary agonists specifi more

News Drug Development

• Merck Licenses CRISPR Gene-Editing Technology to Evotec
  

  Merck announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for more

• Evotec reaches milestone in integrated drug discovery and development partnership with Aeovian

  Evotec SE announced that the Company has reached a milestone in a drug discovery and development partnership with the biopharmaceutical company Aeovian Pharmaceuticals, Inc. Aeovian and Evotec entered into a drug discovery partnership in 2017 to discover and develop new and highly selective mTORC1 i more

• Scientists come up with faster way to discover antibiotics

  Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties. One of the discovered compounds has demonstrated a good activity and low cytotoxicity, and thus can s more

Videos Drug Development

White papers Drug Development

• Real-time and Dynamic Monitoring of Virus-mediated Cytopathogenicity
  

  To understand overall infectivity, virus progression and disease onset it is important to perform a detailed examination of cytopathic effects. Depending on the type of viruses and cells, different cytopathic effects might be observed dependent on th more

• Non-Invasive Real-Time Cell Analytics for Drug Discovery
  

  Roche’s xCELLigence Cardio Instrument is a medium-throughput cell analyzer using impedance recording to monitor cardiac beating and cellular events in real time. The instrument features high resolution detection rate and frequency measurement technol more

• Cytokine Quantification in Drug Development
  

  Immuno-PCR (IPCR) and ElectroChemiLuminescence (ECL) are technologies for improved performance of immunoassays. The specific advantages of the different technologies, using enzymatic or electrical signal amplification, allow for tailored assay design more

Publications Drug Development

• Sample-to-sample p-value variability and its implications for multivariate analysis

  Sample-to-sample p-value variability and its implications for multivariate analysisWei Wang; Wilson Wen Bin GohInternational Journal of Bioinformatics Research and Applications, Vol. 14, No. 3 (2018) pp. 235 - 254Statistical feature selection is used for identification of relevant genes from biolog more

• Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa

  Viruses, Vol. 10, Pages 345: Delivering Phage Products to Combat Antibiotic Resistance in Developing Countries: Lessons Learned from the HIV/AIDS Epidemic in Africa Viruses doi: 10.3390/v10070345 Authors: Tobi E. Nagel The antimicrobial resistance (AMR) crisis and HIV/AIDS epidemic ex more

• Pharmaceuticals, Vol. 11, Pages 64: Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder

  Pharmaceuticals, Vol. 11, Pages 64: Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder Pharmaceuticals doi: 10.3390/ph11030064 Authors: Adwitia Dey Pamela A. Hankey Giblin Over 350 million individuals suffer from depression, a more