Mathematical modelling leads to a better understanding of prostate cancer

3D model depicts processes such as tumour growth

20-Nov-2024 - A team led by Dr Yuri Tolkach at the University of Cologne’s Faculty of Medicine and University Hospital Cologne has investigated prostate tumours and developed an advanced, realistic, three-dimensional model of prostate cancer with the help of mathematical modelling. The model depicts tumour ...

Sleeper cells: Newly discovered stem cell resting phase could put brain tumors to sleep

ASU engineering researchers discover and explore new neural stem cell state that gives insight into cancer

01-Jul-2021 - Christopher Plaisier, an assistant professor of biomedical engineering in the Ira A. Fulton Schools of Engineering at Arizona State University, and Samantha O'Connor, a biomedical engineering doctoral student in the Plaisier Lab, are leading research into a new stage of the stem cell life cycle ...

How obesity drives colon cancer in mice

05-Jul-2018 - Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, revealing potential strategies to combat the disease. Led by assistant ...

A first look at interstitial fluid flow in the brain

05-Jul-2018 - Interstitial fluid transports nutrients and removes waste between the organs and tissues in our body. In the brain, interstitial fluid is thought to be composed of circulating cerebrospinal fluid, cellular waste and blood plasma, and past research has shown a link between interstitial fluid flow ...

Biomarker helps identify 'window of opportunity' for cancer chemotherapy timing

11-Apr-2018 - Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics. Combination therapy using angiogenesis ...

Drug short-circuits cancer signaling

07-Aug-2017 - Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have published a study shedding new light on how K-80003 (TX803), an anti-cancer agent discovered at the Institute, prevents activation of the PI3K pathway, resulting in inhibition of cancer cell growth. Because the PI3K ...

First dual-targeting nanoparticles lower cancer's defenses and attack tumors

09-Jun-2017 - Cancer immunotherapy has emerged as one of the most exciting directions in cancer treatment. But the approach only works in a fraction of patients and can cause nasty side effects. Now scientists report the development of the first dual-cell targeting immunotherapy nanoparticle that slows tumor ...

Gene-based blood tests identify more skin cancers

03-Apr-2017 - Genetic testing of tumor and blood fluid samples from people with and without one of the most aggressive forms of skin cancer has shown that two new blood tests can reliably detect previously unidentifiable forms of the disease. Researchers at NYU Langone Medical Center and its Perlmutter Cancer ...

Metabolic pathway that drives tumor growth in aggressive cancers

03-Mar-2017 - Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in ...

Liver tumor growth in mice slowed with new chemo-immunotherapy treatment

02-Mar-2017 - Hepatocellular carcinoma is the most common form of liver cancer, but treatment options are limited and many patients are diagnosed in late stages when the disease can't be treated. Now, University of Missouri School of Medicine researchers have developed a new treatment that combines ...