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The Swiss biotech company originates from the groups of Prof. Karl-Heinz Krause as well as Prof. Luc Stoppini. Prof. Karl-Heinz KRAUSE, as a clinical researcher at the University Hospitals and University of Geneva, is mainly interested in pluripotent stem cells, neural differentiation and reactive o more
With a new high-tech 3D stem cell technology Braingineering Technologies (BTech), a designated spin-off of the Luxembourg Centre for Systems Biomedicine (LCSB), supports pharmaceutical companies in the drug discovery and preclinical testing phase to increase their efficiency and the success rate of more
Scientists were able to model a developmental disorder called neuronal heterotopia which can lead to intellectual disability and epilepsy. They used a model of brain development called brain organoids where human cells organize themselves in the petri dish into brain-like structures. Brain organoids more
In old age, the amount of stem cells in the brains of mice decreases drastically. The remaining ones protect themselves from completely vanishing by entering a state of dormancy, scientists from the German Cancer Research Center (DKFZ) have now reported in "CELL". The old stem cells are hard to awak more
Cell replacement may play an increasing role in alleviating the motor symptoms of Parkinson's disease (PD) in future. Writing in a special supplement to the Journal of Parkinson's Disease, experts describe how newly developed stem cell technologies could be used to treat the disease and discuss the more
Researchers at Columbia University Medical Center have developed three-dimensional lung bud "organoids" from human pluripotent stem cells. The "mini organs" could be used to model lung diseases such as pulmonary fibrosis and respiratory syncytial virus infection.The research was carried out in t ... more
An MRI shows stem cells labeled with iron oxide nanoparticles being injected into an animal’s brain. more
Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing more
Secure sample storage plays a critical role in a wide range of medical and life science projects today where there is a need to maintain often very large numbers of biological samples at low and stable temperatures for long periods. Globally, close more
The Roche Innovats product line is now available from Roche Applied Sciences. Below is a short introduction to three Roche Innovatis product lines designed for the complete analysis of cell cultures, from the simple determination of cell concentratio more
Experimentation involving human stem cells (HSCs) is one of the fastest growing fields in research and development due, in large part, to its potential for revolutionizing human disease treatment. There are multiple HSC platforms being investigated, including human mesenchymal stem cells (hMSCs) an
It has been a decade since Shinya Yamanaka and Kazutoshi Takahashi first reported the Nobel Prize winning discovery of induced pluripotent stem cells (iPSCs). Since then the technology has created new opportunities in understanding human development and has become an important tool in disease modeli
PSCs represent an important tool in a wide range of applications, including basic research, disease modeling, drug discovery, and regenerative medicine. As stem cell cultures are very sensitive and respond to the smallest influence, stable culture conditions are crucial to maintain reliability and r
The stem cell niche is a specialized environment that dictates stem cell function during development and homeostasis. We show that Dll1, a Notch pathway ligand, is enriched in mammary gland stem cells (MaSCs) and mediates critical interactions with stromal macrophages in the surrounding niche in mo more
Stem Cells Macrophages engulf damaged and dead cells to clear infection, but they also participate in tissue regeneration. Chakrabarti et al. expand the macrophage repertoire for mammary gland development (see the Perspective by Kannan and Eaves). Mammary gland stem cells secrete the Notch ligand more
The adult mammary gland is a bilayered branching epithelial structure consisting of an outer layer of basal cells and an inner layer of luminal cells. The neonatal structure expands rapidly during puberty and then undergoes cyclic growth in response to the changing hormonal stimuli (progesterone and more
GBI Research, a leading business intelligence provider, has released its latest research, entitled “Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets”. The report is built using data and information sourced from more
BMI View: The prospects for Japan’s pharmaceutical market over the medium term are very positive. The country has one of the largest pensionable populations, healthcare is readily accessible, the government appreciates investment in biomedical research and the regulatory regime balances the requirem more
GBI Research, the leading business intelligence provider, has released its latest research, “Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications”, which provides insights into the global regenerative medicin more
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