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Takara Bio Europe is a wholly owned subsidiary of Takara Bio Inc., who develops, manufactures, and distributes a wide range of life science reagents under the Takara™, Clontech®, and Cellartis® brands. Key products include SMART cDNA synthesis kits for a variety of samples and applications, includ more
We are a leading system provider of microporous filter membranes and injection molded components. Founded in 1958 by the Sander-Beuermann family, we have two plants in Germany today and are part of the family owned Altenloh, Brinck & Co. Group with above 1,600 employees around the world and combined more
Merck Millipore is the Life Science division of Merck KGaA of Germany and offers a broad range of innovative, performance products, services and business relationships that enable our customers’ success in research, development and production of biotech and pharmaceutical drug therapies. Through ded more
An international team of researchers from the Universities of Cologne and Helsinki have discovered that the ability of stem cells to proliferate and renew organs is regulated by the stiffness of the surrounding tissue. This finding may have implications for improving the regeneration of aged tissue. more
When the causes of serious diseases are based on a defective gene, medicine relies on gene therapy. In this strategy, defect-free genes are introduced into the body with the help of certain viruses. In this way, individual forms of congenital blindness, hereditary muscular atrophy or certain disease more
Dormancy is a sleep-like state of cells that protects them from genetic damage and thus prolongs their survival. This state is reversible and characterized by low metabolic activity and division rate. Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) and the University more
An MRI shows stem cells labeled with iron oxide nanoparticles being injected into an animal’s brain. more
Researchers at Columbia University Medical Center have developed three-dimensional lung bud "organoids" from human pluripotent stem cells. The "mini organs" could be used to model lung diseases such as pulmonary fibrosis and respiratory syncytial virus infection.The research was carried out in t ... more
Secure sample storage plays a critical role in a wide range of medical and life science projects today where there is a need to maintain often very large numbers of biological samples at low and stable temperatures for long periods. Globally, close more
The stem cell niche is a specialized environment that dictates stem cell function during development and homeostasis. We show that Dll1, a Notch pathway ligand, is enriched in mammary gland stem cells (MaSCs) and mediates critical interactions with stromal macrophages in the surrounding niche in mo more
Stem Cells Macrophages engulf damaged and dead cells to clear infection, but they also participate in tissue regeneration. Chakrabarti et al. expand the macrophage repertoire for mammary gland development (see the Perspective by Kannan and Eaves). Mammary gland stem cells secrete the Notch ligand more
The adult mammary gland is a bilayered branching epithelial structure consisting of an outer layer of basal cells and an inner layer of luminal cells. The neonatal structure expands rapidly during puberty and then undergoes cyclic growth in response to the changing hormonal stimuli (progesterone and more
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