Sartocon Q Hydrosart 30k Da

The Sartocon^® Q Hydrosart^® 30 kDa mAb represents a breakthrough in tangential flow filtration technology, specifically engineered for fast and efficient monoclonal antibody processing. This innovative cassette combines a stabilized cellulose membrane with the mAb‑optimized Q‑Screen channel architecture to deliver superior performance in concentration, ultrafiltration, and diafiltration.

The Hydrosart^® membrane features a hydrophilic, non‑protein‑binding surface that supports high yields by minimizing nonspecific adsorption. With a 30 kDa molecular weight cutoff optimized for mAbs, it maintains consistent performance across a broad operating range and remains practically non‑fouling even after multiple use cycles.

The advanced Q‑Screen design is positioned between ECO and E‑Screen and is optimized for mAb processing. The self‑sealing format removes the need for separate gaskets, while enlarged ports help reduce system pressure drop for efficient operation.

Available in multiple size formats from development scale (172 cm²) to large‑scale production (3.09 m²), the platform offers fully scalable solutions from lab development through commercial manufacturing. The robust design delivers consistent performance after caustic cleaning and depyrogenation procedures, supporting reliable repeated use.

Key applications include mAb concentration prior to formulation, buffer exchange through diafiltration, volume reduction, and end‑to‑end TFF process development through manufacturing scale‑up.

Optional: This new cassette uses no PFAS‑containing materials.