Dr. Judith Wortmann, Michael Ostendorf, Dr. Friederike Becker

Strategic peptide purification

Practical and theoretical aspects of method development using reversed phase chromatography

Peptides belong to one of the most important biopharmaceutical groups as they have a broad spectrum of applications. The impurity profile of these molecules is just as fascinating as the range of chemical properties. Therefore, the purification via preparative reversed phase chromatography (RP-LC) is ideal. Therefore, YMC has now summarised expert knowledge, so that you always have practical tips at hand. In the whitepaper “Strategic peptide purification”, you’ll find specific case studies and practically authenticated guidelines: Important criteria of phase selection, which consider the preparative aspects. The focus is on modern stationary phases that allow robust and efficient methods. Clearly illustrated: How the analytical method development can be transferred to a robust preparative method. But this is not all: Loadability studies include more-detailed suggestions.

Your advantages: One comprehensive overview including many expert tips. Download here your practical guidelines for safe and robust method development

Facts, background information, dossiers
  • method development
  • peptide purification
  • Chromatography para…
  • Loadability studies
  • Process cost optimisation
  • Process scale purification
  • Purification of Bilogicals
  • Reversed phase chro…
  • Scale-up in chromatography
  • Selection of statio…
More about YMC
  • White papers

    Strategic peptide purification

    A comprehensive overview article with many expert tips more

  • Products

    Biocompatible pilot scale glass columns

    Fast and bubble-free piston assembly due to the innovative drain function ✓ Unpacking and cleaning of the column is easily performed with the removable column body ✓ Permanent sealing and extremely small dead areas provided by the unique sealing principle ✓ more

  • Videos

    YMC Europe GmbH


  • Companies

    YMC Europe GmbH

    YMC Europe offers a wide range of HPLC columns, high flow rate preparative LC systems, bulk silica media for preparative chromatography and lab- and pilot-scale glass columns for customer packing. In addition we provide an on demand service for application support and method development. ... more