PharmaGap and MD Biosciences Announce a Collaboration to Pursue Development of a Novel PKC Theta Inhibitor

18-Mar-2009 - PharmaGap Inc. and MD Biosciences GmbH have entered into a co-development collaboration pertaining to novel compounds for therapeutic usage in inflammatory and neurological applications, including potentially arthritis and multiple sclerosis. MD Biosciences has been granted exclusive access to a ...

Scripps research team identifies key molecules that inhibit viral production

Discovery may aid in the development of anti-hepatitis C virus drugs

12-Mar-2009 - In a new study, Professor Donny Strosberg of Scripps Florida and his colleagues describe peptides derived from the core protein of hepatitis C. The team found that these peptides inhibit not only dimerization of the core protein, but also production of the actual virus itself. With over 170 ...

Mayo Clinic researchers discover drug can prevent colon cancer development in mice

13-Feb-2009 - Researchers at the Mayo Clinic campus in Florida have found that a drug now being tested to treat a range of human cancers significantly inhibited colon cancer development in mice. Because the agent appears to have minimal side effects, it may represent an effective chemopreventive treatment in ...

Zedira receives a research grant of 750,000 Euros for the development of novel compounds for thromboprophylaxis

06-Feb-2009 - As part of the funding program "KMU-innovativ", Zedira will receive a research grant of 750,000 Euros over a period of two years from the Federal Ministry of Education and Research. Zedira plans to expand its drug development pipeline based on proprietary inhibitors that specifically target blood ...

Mosquito genes linked to insecticide resistance may be new target in fight against malaria

05-Feb-2009 - Malaria remains one of the most serious diseases worldwide, claiming the lives of more than one million people per year in tropical and sub-tropical regions, the majority of whom are children under five years of age. Efforts to eliminate this mosquito-borne illness rely heavily on prevention ...

Researchers 'unzip' molecules to measure interactions keeping DNA packed in cells

29-Jan-2009 - Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly - and then to pull hard. A Cornell research team's experiments involve the "unzipping" of single DNA molecules. By mapping the hiccups, stoppages and forces along the way, they have gained ...

GENEART Receives European Patent for Selective Evolution of Proteins

European Patent Office grants patent titled "Method for carrying out the selective evolution of proteins in vitro"

22-Jan-2009 - GENEART AG informs about patent EP 1913140 titled "Verfahren für die kontinuierliche, zielgerichtete Evolution von Proteinen in vitro" ("Method for carrying out the selective evolution of proteins in vitro") being granted by the European Patent Office. The patent protects a procedure for the ...

Strategic Collaboration between Genencor and BRAIN

Genencor and BRAIN establish a research collaboration for the biotechnological production of biobased chemicals from renewable feedstock

09-Jan-2009 - Genencor, a division of Danisco A/S and BRAIN AG join forces in the field of the biobased fermentative production of industrially relevant biochemicals from renewable raw materials. Genencor will use its capabilities in metabolic pathway engineering and biomanufacturing of industrial bio-products ...

Galapagos extends drug discovery collaboration with Amgen into 2010

22-Dec-2008 - Galapagos NV announced that its service division BioFocus DPI has extended its longstanding drug discovery collaboration with Amgen through 2009 and 2010. BioFocus DPI will continue to provide biology, computational and medicinal chemistry services and will supply small molecule compounds for ...

New technique provides snapshot of all genes being transcribed across human genome

18-Dec-2008 - Like Silly Putty lifting an imprint of the Sunday comics off a newspaper, complex enzymes called RNA polymerases lift information off DNA strands. The polymerases then transcribe those genetic instructions onto RNA for making proteins that cells use for basic functions. In Science, Cornell ...