US company acquires spin-off from Jacobs University researchers

31-Mar-2021 - Two years ago, Sebastian Springer, Professor of Biochemistry and Cell Biology at Jacobs University Bremen, founded Tetramer-Shop together with scientists from the Technical University of Denmark. Now the pioneer in biomedical reagents for cancer diagnostics, based in Copenhagen, has been sold to ...

Drug to rejuvenate muscle cells developed

Elderly to feel fitter, faster and stronger

18-Feb-2019 - Researchers from The University of Texas Medical Branch at Galveston have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a study. As we age, our bodies increasingly lose the ability to repair and rebuild ...

Theory unlocks the secret behind protein-membrane interactions

Understanding cell behavior better by elucidating how proteins work with cell membranes

28-Jan-2019 - Trillions of cells -- all different shapes and sizes -- form a human body's structure. Surrounding each cell is a membrane, jointly acting as hostess and security -- welcoming certain information into the cell while making sure its components don't spill out into the body's void. Much is known ...

New sepsis therapy approaches with evolution of signaling molecules

Protein engineering extends immune cell vocabulary

25-Jan-2019 - Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system. A new immune signaling molecule, designed by a research team from the Technical University of Munich (TUM), now provides the basis for potential new approaches in sepsis therapy. The ...

New biomarker links cancer progression to genome instability

High level of specific protein in tumors indicates prognosis

14-Jan-2019 - Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat. Genome instability can lead to genetic disorders, chronic ...

AI researchers join forces to develop the 'ImageNet' of generative drug discovery

04-Dec-2018 - Insilico Medicine, an artificial intelligence company developing an end-to-end drug discovery pipeline for age-related diseases, announced an open research collaboration. Researchers are invited to contribute to the new platform MOSES (Molecular Sets), described in the paper titled "Molecular ...

How to produce fluorescent nanoparticles for medical applications in a nuclear reactor

12-Nov-2018 - Under the leadership of Petr Cígler from the Institute of Organic Chemistry and Biochemistry (IOCB Prague) and Martin Hrubý from the Institute of Macromolecular Chemistry (IMC), both of which are part of the Czech Academy of Sciences, a team of researchers has developed a revolutionary method for ...

New drug candidates reverse drug resistance in multiple myeloma in preclinical models

31-Oct-2018 - In an article Medical University of South Carolina investigators report that a new compound enhances the efficacy of proteasome inhibitors (PIs), the standard-of-care for the treatment of multiple myeloma (MM), in cell culture and in preclinical models. The efficacy and safety of the novel ...

Mussel research strenghtens graphene

Polydopamine acts as binder to achieve high mechanical and electrical properties

24-Oct-2018 - Researchers demonstrated the mussel-inspired reinforcement of graphene fibers for the improvement of different material properties. A research group under Professor Sang Ouk Kim applied polydopamine as an effective infiltrate binder to achieve high mechanical and electrical properties for ...

Pathogens may evade immune response with metal-free enzyme required for DNA replication

23-Oct-2018 - Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions. This process may allow infectious bacteria to replicate even when the host's immune system sequesters iron ...