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28 Current news of Universität Bern

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Increasing the effectiveness of immunotherapy against skin cancer

Efficacy of immune checkpoint inhibitors can be improved by the simultaneous administration of IL-32

22-Sep-2020

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells. In the fight against skin cancer, the results have the potential to help immunotherapies succeed, even in patients for whom ...

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Mechanism discovered how the coronavirus hijacks the cell

A starting point for vaccine and drug development

15-Sep-2020

Researchers at ETH Zurich and the University of Bern have discovered a mechanism by which the corona virus manipulates human cells to ensure its own replication. This knowledge will help to develop drugs and vaccines against the corona virus. Like a pirate hijacking a ship, a virus takes control ...

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Gut microbes shape our antibodies before we are infected by pathogens

The range of available antibodies depends on where beneficial microbes are in the body

07-Aug-2020

Colonization with intestinal microbes is known to shape many body systems, especially the white blood cells that produce antibodies. Because the microbiota is so complex, containing hundreds of different bacterial species, it is not known how the presence of microbes in the intestine shaped the ...

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Rapid test for the determination of antibodies against Sars-Cov-2

No elaborate biosafety precautions are necessary

03-Aug-2020

To determine immunity to Sars-Cov-2 and the effectiveness of potential vaccines, the amount of neutralising antibodies in the blood of recovered or vaccinated individuals must be determined. A traditional neutralisation test usually takes two to three days and must be carried out with infectious ...

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Age-related impairments reversed in animal model

Belly fat as a source of chronic inflammation

08-Jul-2020

Frailty and immune decline are two main features of old age. Researchers from the University of Bern and the University Hospital Bern now demonstrate in an animal model that these two age-related impairments can be halted and even partially reversed using a novel cell-based therapeutic ...

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Bern coronavirus clone goes "viral"

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

05-May-2020

Researchers in virology and veterinary bacteriology at the University of Bern have cloned the novel coronavirus (SARS-CoV-2). The synthetic clones are being used by research groups worldwide to test corona samples, find antiviral drugs and develop vaccines as quickly as possible. The method ...

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Algorithms for identifying new "cancer genes"

14-Feb-2020

It is estimated that the number of cancer cases worldwide will double by 2040. This makes the search for genes that cause cancer even more important. A team of researchers from the University of Bern and Inselspital, University Hospital Bern, has now developed algorithms that massively simplify ...

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A new pathway to "reprogram" killer cells

21-Nov-2019

Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells ...

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Breakthrough in malaria research

18-Nov-2019

An international scientific consortium led by the cell biologists Volker Heussler from the University of Bern and Oliver Billker from the Umeå University in Sweden has for the first time systematically investigated the genome of the malaria parasite Plasmodium throughout its life cycle in a ...

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Special cells contribute to regenerate the heart in Zebrafish

24-Oct-2019

It is already known that zebrafish can flexibly regenerate their hearts after injury. An international research group led by Prof. Nadia Mercader of the University of Bern now shows that certain heart muscle cells play a central role in this process. The insights gained could be used to initiate ...

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